(Q47355595)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29131148%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

title

Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29131148%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29131148%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Mehmet Fatih Bolukbasi

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29131148%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Lihua Julie Zhu

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29131148%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Haiwei Mou

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29131148%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Wen Xue

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29131148%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Robert S. Langer, Jr.

20

object named as

Robert Langer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29131148%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Victor E. Koteliansky

17

object named as

Victor Koteliansky

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29131148%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

21

Daniel G Anderson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29131148%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

3

Sneha Suresh

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29131148%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

15

Roman L Bogorad

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29131148%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

18

Scot A Wolfe

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29131148%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

10

Kevin Kauffman

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29131148%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

13

Junmei Ding

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29131148%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

14

Suet-Yan Kwan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29131148%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

author name string

Hao Yin

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29131148%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Chun-Qing Song

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29131148%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Qiongqiong Wu

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29131148%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Stephen Walsh

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29131148%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Luke Hyunsik Rhym

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29131148%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Esther Mintzer

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29131148%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Alicia Oberholzer

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29131148%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

publication date

13 November 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29131148%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29131148%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

volume

35

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29131148%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29131148%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

page(s)

1179-1187

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29131148%20AND%20SRC:MED&resulttype=core&format=json

GUIDEseq: a bioconductor package to analyze GUIDE-Seq datasets for CRISPR-Cas nucleases.

2 April 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

Non-viral delivery of genome-editing nucleases for gene therapy

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

A multifunctional AAV-CRISPR-Cas9 and its host response

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

In vivo gene editing in dystrophic mouse muscle and muscle stem cells

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

Postnatal genome editing partially restores dystrophin expression in a mouse model of muscular dystrophy.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

Beyond editing: repurposing CRISPR-Cas9 for precision genome regulation and interrogation

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

Synthetic CRISPR RNA-Cas9-guided genome editing in human cells

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

DNA-binding-domain fusions enhance the targeting range and precision of Cas9.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

Optimization of Lipid Nanoparticle Formulations for mRNA Delivery in Vivo with Fractional Factorial and Definitive Screening Designs

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

Generation of knock-in primary human T cells using Cas9 ribonucleoproteins.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

STRUCTURAL BIOLOGY. A Cas9-guide RNA complex preorganized for target DNA recognition

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

Adenovirus-Mediated Somatic Genome Editing of Pten by CRISPR/Cas9 in Mouse Liver in Spite of Cas9-Specific Immune Responses.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

Effects of Proprotein Convertase Subtilisin/Kexin Type 9 Antibodies in Adults With Hypercholesterolemia: A Systematic Review and Meta-analysis

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

In vivo genome editing using Staphylococcus aureus Cas9

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

Therapeutic genome editing: prospects and challenges

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

Genome editing. The new frontier of genome engineering with CRISPR-Cas9

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

In vivo interrogation of gene function in the mammalian brain using CRISPR-Cas9

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

Easy quantitative assessment of genome editing by sequence trace decomposition

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

CRISPR-Cas9 knockin mice for genome editing and cancer modeling

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

Non-viral vectors for gene-based therapy

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

RNA-guided human genome engineering via Cas9

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

Multiplex genome engineering using CRISPR/Cas systems

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

Canonical and atypical E2Fs regulate the mammalian endocycle

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

2'-Fluoro RNA shows increased Watson-Crick H-bonding strength and stacking relative to RNA: evidence from NMR and thermodynamic data

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

Designing chemically modified oligonucleotides for targeted gene silencing

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

Current progress of siRNA/shRNA therapeutics in clinical trials

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

State-of-the-art gene-based therapies: the road ahead

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

Organogenesis and development of the liver

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

Lactoferrin protects against acetaminophen-induced liver injury in mice

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

Chemical modification of siRNAs for in vivo use.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

siRNA function in RNAi: a chemical modification analysis

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

Lactoferrin protects against concanavalin A-induced liver injury in mice

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5901668

2'-O-methyl-modified RNAs act as TLR7 antagonists

14 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNBT.4005

inferred from DOI database lookup

7 January 2021

based on heuristic

Rapid discovery of potent siRNA-containing lipid nanoparticles enabled by controlled microfluidic formulation

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNBT.4005

inferred from DOI database lookup

7 January 2021

based on heuristic

Prostaglandin I(2) and E(2) mediate the protective effects of cyclooxygenase-2 in a mouse model of immune-mediated liver injury

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNBT.4005

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NBT.4005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29131148%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29131148%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

PubMed publication ID

29131148

1 reference