(Q47549532)

19 February 2018

title

Efficient inhibition of African swine fever virus replication by CRISPR/Cas9 targeting of the viral p30 gene (CP204L). (English)

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19 February 2018

African swine fever virus

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object named as

African swine fever virus

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5

Thomas C Mettenleiter

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19 February 2018

Alexandra Hübner

1

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19 February 2018

Bjoern Petersen

2

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19 February 2018

Günther M Keil

3

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19 February 2018

Heiner Niemann

4

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19 February 2018

Walter Fuchs

6

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19 February 2018

language of work or name

English

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publication date

23 January 2018

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19 February 2018

published in

Scientific Reports

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19 February 2018

volume

8

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19 February 2018

issue

1

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19 February 2018

page(s)

1449

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19 February 2018

Creative Commons Attribution 4.0 International

copyright license

start time

23 January 2018

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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22 May 2018

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Selection of differently temporally regulated African swine fever virus promoters with variable expression activities and their application for transient and recombinant virus mediated gene expression

22 May 2018

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Precision engineering for PRRSV resistance in pigs: Macrophages from genome edited pigs lacking CD163 SRCR5 domain are fully resistant to both PRRSV genotypes while maintaining biological function

22 May 2018

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22 May 2018

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Transgenic Clustered Regularly Interspaced Short Palindromic Repeat/Cas9-Mediated Viral Gene Targeting for Antiviral Therapy of Bombyx mori Nucleopolyhedrovirus

22 May 2018

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Genetically edited pigs lacking CD163 show no resistance following infection with the African swine fever virus isolate, Georgia 2007/1.

22 May 2018

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Engineering Plant Immunity: Using CRISPR/Cas9 to Generate Virus Resistance

22 May 2018

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Simultaneous Deletion of the 9GL and UK Genes from the African Swine Fever Virus Georgia 2007 Isolate Offers Increased Safety and Protection against Homologous Challenge

22 May 2018

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In vitro inhibition of African swine fever virus-topoisomerase II disrupts viral replication

22 May 2018

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Deletion of African swine fever virus interferon inhibitors from the genome of a virulent isolate reduces virulence in domestic pigs and induces a protective response

22 May 2018

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CRISPR/Cas9-Mediated Genome Editing of Herpesviruses Limits Productive and Latent Infections

22 May 2018

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Transmission routes of African swine fever virus to domestic pigs: current knowledge and future research directions

22 May 2018

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22 May 2018

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CCR5 Disruption in Induced Pluripotent Stem Cells Using CRISPR/Cas9 Provides Selective Resistance of Immune Cells to CCR5-tropic HIV-1 Virus

22 May 2018

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Genome editing of CXCR4 by CRISPR/cas9 confers cells resistant to HIV-1 infection.

22 May 2018

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Efficiently editing the vaccinia virus genome by using the CRISPR-Cas9 system.

22 May 2018

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22 May 2018

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Expression library immunization can confer protection against lethal challenge with African swine fever virus

22 May 2018

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Multiplex genome engineering in human cells using all-in-one CRISPR/Cas9 vector system

22 May 2018

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A novel bromodeoxyuridine-resistant wild boar lung cell line facilitates generation of African swine fever virus recombinants

22 May 2018

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Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease

22 May 2018

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RNA-guided human genome engineering via Cas9

22 May 2018

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Multiplex genome engineering using CRISPR/Cas systems

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780455

African swine fever virus replication and genomics

22 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780455

Review of the sylvatic cycle of African swine fever in sub-Saharan Africa and the Indian ocean.

22 May 2018

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Epidemiology of African swine fever virus

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780455

African swine fever virus transcription

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780455

Novel approach for the generation of recombinant African swine fever virus from a field isolate using GFP expression and 5-bromo-2'-deoxyuridine selection.

22 May 2018

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RNA-guided genetic silencing systems in bacteria and archaea

22 May 2018

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Protection of European domestic pigs from virulent African isolates of African swine fever virus by experimental immunisation.

22 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780455

Genomic analysis of highly virulent Georgia 2007/1 isolate of African swine fever virus.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780455

Control of African swine fever virus replication by small interfering RNA targeting the A151R and VP72 genes

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780455

CRISPR/Cas, the immune system of bacteria and archaea

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780455

Analysis of the complete nucleotide sequence of African swine fever virus

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780455

Structure of African swine fever virus late promoters: requirement of a TATA sequence at the initiation region

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780455

African swine fever virus replication in the midgut epithelium is required for infection of Ornithodoros ticks.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780455

The African swine fever virus proteins p54 and p30 are involved in two distinct steps of virus attachment and both contribute to the antibody-mediated protective immune response

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780455

DNA sequence and transcriptional analysis of the UL1 to UL5 gene cluster of infectious laryngotracheitis virus

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780455

Sequence and characterization of the major early phosphoprotein p32 of African swine fever virus

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780455

Interaction of African swine fever virus with macrophages

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780455

Characterization of p30, a highly antigenic membrane and secreted protein of African swine fever virus

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780455

Gene-edited pigs are protected from porcine reproductive and respiratory syndrome virus

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780455

Live vaccination with an H5-hemagglutinin-expressing infectious laryngotracheitis virus recombinant protects chickens against different highly pathogenic avian influenza viruses of the H5 subtype

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5780455

CRISPR/Cas9-Mediated Gene Targeting during Embryogenesis in Swine

14 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FS41598-018-19626-1

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/S41598-018-19626-1

1 reference

19 February 2018

PMC publication ID

5780455

1 reference

19 February 2018

PubMed publication ID

29362418

1 reference

19 February 2018