(Q47566392)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28346452%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

title

Purine synthesis promotes maintenance of brain tumor initiating cells in glioma (English)

1 reference

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14 March 2020

1 reference

13

1 reference

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14 March 2020

Xiuxing Wang

1

1 reference

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14 March 2020

Kailin Yang

2

1 reference

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14 March 2020

Stephen C Mack

5

1 reference

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14 March 2020

Mario L Suvà

18

1 reference

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14 March 2020

Jason W. Locasale

20

1 reference

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14 March 2020

17

Aviv Regev

1 reference

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14 March 2020

22

Jeremy N Rich

1 reference

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14 March 2020

author name string

Qi Xie

3

1 reference

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14 March 2020

Qiulian Wu

4

1 reference

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14 March 2020

Yu Shi

6

1 reference

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14 March 2020

Leo J Y Kim

7

1 reference

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14 March 2020

Briana C Prager

8

1 reference

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14 March 2020

William A Flavahan

9

1 reference

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14 March 2020

Xiaojing Liu

10

1 reference

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14 March 2020

Meromit Singer

11

1 reference

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14 March 2020

Christopher G Hubert

12

1 reference

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14 March 2020

Wenchao Zhou

14

1 reference

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14 March 2020

Zhi Huang

15

1 reference

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14 March 2020

Xiaoguang Fang

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28346452%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

Tae Hyun Hwang

19

1 reference

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14 March 2020

Shideng Bao

21

1 reference

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14 March 2020

language of work or name

English

0 references

publication date

27 March 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28346452%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28346452%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

volume

20

1 reference

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14 March 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28346452%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

page(s)

661-673

1 reference

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https://scigraph.springernature.com/pub.10.1038/nn.4537

14 March 2020

exact match

0 references

cites work

From Krebs to clinic: glutamine metabolism to cancer therapy.

1 reference

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Amino Acids Rather than Glucose Account for the Majority of Cell Mass in Proliferating Mammalian Cells

10 July 2018

1 reference

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mTORC1 induces purine synthesis through control of the mitochondrial tetrahydrofolate cycle

10 July 2018

1 reference

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Metabolic Heterogeneity in Human Lung Tumors.

10 July 2018

1 reference

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The Emerging Hallmarks of Cancer Metabolism

10 July 2018

1 reference

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MYC, Metabolism, and Cancer

10 July 2018

1 reference

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Glucose-dependent acetylation of Rictor promotes targeted cancer therapy resistance

10 July 2018

1 reference

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Mitochondrial control by DRP1 in brain tumor initiating cells

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6015494

Regulation of mammalian nucleotide metabolism and biosynthesis

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6015494

The zinc finger transcription factor ZFX is required for maintaining the tumorigenic potential of glioblastoma stem cells

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6015494

Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6015494

Discrete mechanisms of mTOR and cell cycle regulation by AMPK agonists independent of AMPK.

10 July 2018

1 reference

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Neural stem cells: generating and regenerating the brain

10 July 2018

1 reference

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Therapeutic targeting of constitutive PARP activation compromises stem cell phenotype and survival of glioblastoma-initiating cells

10 July 2018

1 reference

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The somatic genomic landscape of glioblastoma

10 July 2018

1 reference

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Brain tumor initiating cells adapt to restricted nutrition through preferential glucose uptake.

10 July 2018

1 reference

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Glioblastoma stem cells generate vascular pericytes to support vessel function and tumor growth.

10 July 2018

1 reference

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Current clinical development of PI3K pathway inhibitors in glioblastoma

10 July 2018

1 reference

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Metabolic reprogramming: a cancer hallmark even warburg did not anticipate

10 July 2018

1 reference

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IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6015494

Phase I, dose-escalation study of BKM120, an oral pan-Class I PI3K inhibitor, in patients with advanced solid tumors

10 July 2018

1 reference

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The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming

10 July 2018

1 reference

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Targeting cancer metabolism: a therapeutic window opens

10 July 2018

1 reference

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Acidic stress promotes a glioma stem cell phenotype.

10 July 2018

1 reference

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The AMPK agonist AICAR inhibits the growth of EGFRvIII-expressing glioblastomas by inhibiting lipogenesis

10 July 2018

1 reference

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Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells

10 July 2018

1 reference

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Understanding the Warburg effect: the metabolic requirements of cell proliferation

10 July 2018

1 reference

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SSEA-1 is an enrichment marker for tumor-initiating cells in human glioblastoma

10 July 2018

1 reference

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Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

10 July 2018

1 reference

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IDH1 and IDH2 mutations in gliomas

10 July 2018

1 reference

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Rembrandt: helping personalized medicine become a reality through integrative translational research

10 July 2018

1 reference

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The molecular determinants of de novo nucleotide biosynthesis in cancer cells

10 July 2018

1 reference

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Association between hyperglycemia and survival in patients with newly diagnosed glioblastoma

10 July 2018

1 reference

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The phosphatidylinositol 3-kinase/akt cassette regulates purine nucleotide synthesis

10 July 2018

1 reference

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c-Myc is required for maintenance of glioma cancer stem cells

10 July 2018

1 reference

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p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation

10 July 2018

1 reference

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Brain cancer stem cells display preferential sensitivity to Akt inhibition

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6015494

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6015494

Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6015494

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6015494

Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6015494

Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6015494

Identification of human brain tumour initiating cells

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6015494

Transforming growth factor beta2 promotes glucose carbon incorporation into nucleic acid ribose through the nonoxidative pentose cycle in lung epithelial carcinoma cells

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6015494

Broad-spectrum antiviral activity of the IMP dehydrogenase inhibitor VX-497: a comparison with ribavirin and demonstration of antiviral additivity with alpha interferon

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6015494

Molecular mechanisms of action of new xenobiotic immunosuppressive drugs: tacrolimus (FK506), sirolimus (rapamycin), mycophenolate mofetil and leflunomide

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6015494

Structure and mechanism of inosine monophosphate dehydrogenase in complex with the immunosuppressant mycophenolic acid

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6015494

Broad-spectrum antiviral activity of Virazole: 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6015494

Mode of action of ribavirin: effect of nucleotide pool alterations on influenza virus ribonucleoprotein synthesis

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6015494

Physiological functions of the pentose phosphate pathway

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6015494

Gene expression profiling of gliomas strongly predicts survival

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6015494

Systemic lupus erythematosus

14 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNN.4537

21 January 2018

Identifiers

DOI

10.1038/NN.4537

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28346452%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28346452%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

PubMed publication ID

28346452

1 reference