(Q47590783)

4 February 2018

http://europepmc.org/abstract/MED/29080858

title

Tailored first-line and second-line CDK4-targeting treatment combinations in mouse models of pancreatic cancer (English)

1 reference

4 February 2018

http://europepmc.org/abstract/MED/29080858

author

Andrew Burgess

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29080858%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Sean Grimmond

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29080858%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Thomas R Cox

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29080858%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Marina Pajic

33

1 reference

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6 June 2020

Lorraine A Chantrill

15

1 reference

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6 June 2020

Mark J. Cowley

16

1 reference

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6 June 2020

Nicola J Waddell

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29080858%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Owen J Sansom

24

1 reference

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6 June 2020

Jennifer P. Morton

25

1 reference

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6 June 2020

Shane T Grey

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29080858%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Stephen Clarke

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29080858%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

23

Andrew V Biankin

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29080858%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

3

Adnan M Nagrial

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29080858%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

author name string

Angela Chou

1

1 reference

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6 June 2020

Danielle Froio

2

1 reference

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6 June 2020

Ashleigh Parkin

4

1 reference

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6 June 2020

Kendelle J Murphy

5

1 reference

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6 June 2020

Dalia Wohl

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29080858%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Angela Steinmann

8

1 reference

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6 June 2020

Rhys Stark

9

1 reference

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6 June 2020

Alison Drury

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29080858%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Stacey N Walters

11

1 reference

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6 June 2020

Claire Vennin

12

1 reference

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6 June 2020

Mark Pinese

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29080858%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Timothy J Molloy

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29080858%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Australian Pancreatic Cancer Genome Initiative (APGI)

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29080858%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Amber Johns

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29080858%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

David K Chang

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29080858%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

John Turchini

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29080858%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Jaswinder Samra

29

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6 June 2020

Paul Timpson

31

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29080858%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Anthony J Gill

32

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29080858%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Venessa T Chin

6

1 reference

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6 June 2020

language of work or name

English

0 references

publication date

28 October 2017

1 reference

4 February 2018

http://europepmc.org/abstract/MED/29080858

published in

Gut

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29080858%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

volume

67

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29080858%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29080858%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

page(s)

2142-2155

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29080858%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

1 reference

12 December 2020

Visualizing spatiotemporal dynamics of multicellular cell-cycle progression

1 reference

12 December 2020

Resistance to fluid shear stress is a conserved biophysical property of malignant cells

1 reference

12 December 2020

Stromal disrupting effects of nab-paclitaxel in pancreatic cancer

1 reference

12 December 2020

Abrogation of the Rb/p16 tumor-suppressive pathway in virtually all pancreatic carcinomas

1 reference

12 December 2020

Substrate Rigidity Controls Activation and Durotaxis in Pancreatic Stellate Cells

1 reference

12 December 2020

Regulation of pancreatic cancer aggressiveness by stromal stiffening

1 reference

12 December 2020

Targeting mTOR dependency in pancreatic cancer

1 reference

12 December 2020

Cell-cycle reprogramming for PI3K inhibition overrides a relapse-specific C481S BTK mutation revealed by longitudinal functional genomics in mantle cell lymphoma

1 reference

12 December 2020

Force Matters: Biomechanical Regulation of Cell Invasion and Migration in Disease

1 reference

12 December 2020

Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis.

1 reference

12 December 2020

Selective impact of CDK4/6 suppression on patient-derived models of pancreatic cancer

1 reference

12 December 2020

Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy

1 reference

12 December 2020

Gemcitabine-mediated tumour regression and p53-dependent gene expression: implications for colon and pancreatic cancer therapy

1 reference

12 December 2020

Margin clearance and outcome in resected pancreatic cancer

1 reference

12 December 2020

FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer

1 reference

12 December 2020

Increased survival in pancreatic cancer with nab-paclitaxel plus gemcitabine

1 reference

12 December 2020

Gemcitabine plus erlotinib followed by capecitabine versus capecitabine plus erlotinib followed by gemcitabine in advanced pancreatic cancer: final results of a randomised phase 3 trial of the 'Arbeitsgemeinschaft Internistische Onkologie' (AIO-PK01

1 reference

12 December 2020

Spatial regulation of RhoA activity during pancreatic cancer cell invasion driven by mutant p53

1 reference

12 December 2020

Contrasting quiescent G0 phase with mitotic cell cycling in the mouse immune system

1 reference

12 December 2020

The cell-cycle regulator CDK4: an emerging therapeutic target in melanoma

1 reference

12 December 2020

Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma

1 reference

12 December 2020

Cdk4/6 inhibition induces epithelial-mesenchymal transition and enhances invasiveness in pancreatic cancer cells

1 reference

12 December 2020

ISDoT: in situ decellularization of tissues for high-resolution imaging and proteomic analysis of native extracellular matrix.

1 reference

12 December 2020

CDK4/6-dependent activation of DUB3 regulates cancer metastasis through SNAIL1.

1 reference

12 December 2020

Personalized therapy for pancreatic cancer: Do we need better targets, arrows, or both?

1 reference

12 December 2020

Moderate Increase in Mdr1a/1b Expression Causes In vivo Resistance to Doxorubicin in a Mouse Model for Hereditary Breast Cancer

1 reference

12 December 2020

Meta-analysis of immunohistochemical prognostic markers in resected pancreatic cancer.

1 reference

12 December 2020

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

1 reference

12 December 2020

Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression

1 reference

12 December 2020

Desmoplastic reaction in pancreatic cancer: role of pancreatic stellate cells

1 reference

12 December 2020

Fulvestrant plus palbociclib versus fulvestrant plus placebo for treatment of hormone-receptor-positive, HER2-negative metastatic breast cancer that progressed on previous endocrine therapy (PALOMA-3): final analysis of the multicentre, double-blind

1 reference

12 December 2020

MONARCH 2: Abemaciclib in Combination With Fulvestrant in Women With HR+/HER2- Advanced Breast Cancer Who Had Progressed While Receiving Endocrine Therapy.

1 reference

12 December 2020

p16-Cdk4-Rb axis controls sensitivity to a cyclin-dependent kinase inhibitor PD0332991 in glioblastoma xenograft cells

1 reference

12 December 2020

Whole genomes redefine the mutational landscape of pancreatic cancer

1 reference

12 December 2020

Drug combination studies and their synergy quantification using the Chou-Talalay method

1 reference

12 December 2020

Clinical Cancer Advances 2016: Annual Report on Progress Against Cancer From the American Society of Clinical Oncology

1 reference

12 December 2020

CDK4/6 inhibition triggers anti-tumour immunity.

1 reference

12 December 2020

Phase I trial of palbociclib, a selective cyclin dependent kinase 4/6 inhibitor, in combination with cetuximab in patients with recurrent/metastatic head and neck squamous cell carcinoma

1 reference

12 December 2020

A kinase-independent function of CDK6 links the cell cycle to tumor angiogenesis

1 reference

12 December 2020

Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice

1 reference

12 December 2020

The cyclin-dependent kinase 4/6 inhibitor palbociclib in combination with letrozole versus letrozole alone as first-line treatment of oestrogen receptor-positive, HER2-negative, advanced breast cancer (PALOMA-1/TRIO-18): a randomised phase 2 study

1 reference

12 December 2020

Progression-Free Survival Among Patients With Well-Differentiated or Dedifferentiated Liposarcoma Treated With CDK4 Inhibitor Palbociclib: A Phase 2 Clinical Trial.

1 reference

12 December 2020

Expression of p16 and retinoblastoma determines response to CDK4/6 inhibition in ovarian cancer

1 reference

12 December 2020

RB-pathway disruption is associated with improved response to neoadjuvant chemotherapy in breast cancer

1 reference

12 December 2020

Blocking the Cycle: Cyclin-Dependent Kinase 4/6 Inhibitors in Metastatic, Hormone Receptor-Positive Breast Cancer

1 reference

12 December 2020

Rho-kinase/ROCK is involved in cytokinesis through the phosphorylation of myosin light chain and not ezrin/radixin/moesin proteins at the cleavage furrow.

1 reference

12 December 2020

Genomic analyses identify molecular subtypes of pancreatic cancer

1 reference

12 December 2020

Selected alkylating agents can overcome drug tolerance of G0-like tumor cells and eradicate BRCA1-deficient mammary tumors in mice

1 reference

12 December 2020

A starring role for stellate cells in the pancreatic cancer microenvironment

1 reference

12 December 2020

Preclinical characterization of the CDK4/6 inhibitor LY2835219: in-vivo cell cycle-dependent/independent anti-tumor activities alone/in combination with gemcitabine

1 reference

12 December 2020

Intravital microscopy through an abdominal imaging window reveals a pre-micrometastasis stage during liver metastasis

1 reference

12 December 2020

Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial

1 reference

12 December 2020

Treating cancer with selective CDK4/6 inhibitors

1 reference

12 December 2020

A global suppressor motif for p53 cancer mutants

1 reference

12 December 2020

10.1136/GUTJNL-2017-315144

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29080858%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29080858%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

1 reference