(Q38791499)

6 September 2017

Genomic analyses identify molecular subtypes of pancreatic cancer (English)

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Marc D. Jones

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Jennifer P. Morton

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Marina Pajic

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Neil D. Merrett

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Mark J. Cowley

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Nicole Cloonan

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Sean Grimmond

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Andrew Biankin

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Robert Grützmann

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Robert Grützmann

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Marc Giry-Laterriere

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Marc Giry-Laterriere

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Lorraine A Chantrill

Lorraine A Chantrill

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Christian Pilarsky

Christian Pilarsky

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Peter J Bailey

Peter Bailey

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Andreia V Pinho

Andreia V Pinho

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Mark Pinese

Mark Pinese

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Rita A Lawlor

Rita T Lawlor

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Roberto Salvia

Roberto Salvia

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Nicola J Waddell

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Nicola Waddell

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Venessa Chin

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Lynn Fink

Lynn Fink

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James G Kench

James G Kench

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Aldo Scarpa

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Aldo Scarpa

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Christine A Iacobuzio-Donahue

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Christine A Iacobuzio-Donahue

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Ralph H Hruban

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Christopher L Wolfgang

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Christopher L Wolfgang

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Anirban Maitra

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Gloria M Petersen

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Claudio Bassi

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Giampaolo Tortora

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Australian Pancreatic Cancer Genome Initiative

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Australian Pancreatic Cancer Genome Initiative

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Adnan M Nagrial

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David K Chang

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L Charles Murtaugh

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Ehsan Nourbakhsh

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Shivangi Wani

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Oliver Holmes

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Stephen Kazakoff

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Conrad Leonard

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Felicity Newell

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Scott Wood

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Qinying Xu

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Peter J Wilson

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Karin S Kassahn

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Darrin Taylor

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Kelly Quek

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Alan Robertson

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Lorena Pantano

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Laura Mincarelli

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Luis N Sanchez

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Lisa Evers

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Jianmin Wu

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Emily K Colvin

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Emily S Humphrey

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Amanda Mawson

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Jeremy Humphris

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Angela Chou

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Jaswinder S Samra

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Krishna Epari

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Nam Q Nguyen

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Andrew Barbour

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Nikolajs Zeps

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Kim Moran-Jones

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Nigel B Jamieson

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Janet S Graham

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Fraser Duthie

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Karin Oien

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Jane Hair

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Richard A Morgan

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Borislav Rusev

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Debabrata Mukhopadhyay

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William E Fisher

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Ulla-Maja Hagbo Bailey

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language of work or name

English

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publication date

24 February 2016

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6 September 2017

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531

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47-52

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7592

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https://scigraph.springernature.com/pub.10.1038/nature16965

6 September 2017

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cites work

Projecting cancer incidence and deaths to 2030: the unexpected burden of thyroid, liver, and pancreas cancers in the United States

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https://api.crossref.org/works/10.1038%2FNATURE16965

Whole genomes redefine the mutational landscape of pancreatic cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE16965

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

21 January 2018

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Whole-exome sequencing of human pancreatic cancers and characterization of genomic instability caused by MLH1 haploinsufficiency and complete deficiency

21 January 2018

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Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

21 January 2018

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Deciphering signatures of mutational processes operative in human cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE16965

Genome-wide DNA methylation patterns in pancreatic ductal adenocarcinoma reveal epigenetic deregulation of SLIT-ROBO, ITGA2 and MET signaling.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE16965

Genomic catastrophes frequently arise in esophageal adenocarcinoma and drive tumorigenesis.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE16965

Whole-genome characterization of chemoresistant ovarian cancer.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE16965

Comprehensive molecular profiling of lung adenocarcinoma

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE16965

RBM5, 6, and 10 differentially regulate NUMB alternative splicing to control cancer cell proliferation

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE16965

Acquired mutations that affect pre-mRNA splicing in hematologic malignancies and solid tumors

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE16965

SF3B1 mutations constitute a novel therapeutic target in breast cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE16965

Mind bomb 1 is required for pancreatic β-cell formation

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE16965

Cyclin E amplification/overexpression is a mechanism of trastuzumab resistance in HER2+ breast cancer patients

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE16965

Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE16965

Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE16965

Adenosquamous carcinoma of the pancreas harbors KRAS2, DPC4 and TP53 molecular alterations similar to pancreatic ductal adenocarcinoma.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE16965

Emerging from the shade of p53 mutants: N-terminally truncated variants of the p53 family in EMT signaling and cancer progression

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE16965

The homeodomain protein PDX1 is required at mid-pancreatic development for the formation of the exocrine pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE16965

Nr5a2 maintains acinar cell differentiation and constrains oncogenic Kras-mediated pancreatic neoplastic initiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE16965

The nuclear hormone receptor family member NR5A2 controls aspects of multipotent progenitor cell formation and acinar differentiation during pancreatic organogenesis

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE16965

Molecular and genetic properties of tumors associated with local immune cytolytic activity

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE16965

Mutant p53 drives pancreatic cancer metastasis through cell-autonomous PDGF receptor β signaling

21 January 2018

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Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy.

21 January 2018

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Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy

21 January 2018

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Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinoma.

21 January 2018

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The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data

21 January 2018

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Mutational heterogeneity in cancer and the search for new cancer-associated genes

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE16965

IntOGen-mutations identifies cancer drivers across tumor types.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE16965

Pan-cancer network analysis identifies combinations of rare somatic mutations across pathways and protein complexes

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE16965

iRefIndex: a consolidated protein interaction database with provenance

21 January 2018

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RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

21 January 2018

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STAR: ultrafast universal RNA-seq aligner

21 January 2018

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featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

21 January 2018

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Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

21 January 2018

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The sva package for removing batch effects and other unwanted variation in high-throughput experiments

21 January 2018

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ConsensusClusterPlus: a class discovery tool with confidence assessments and item tracking

21 January 2018

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GSVA: gene set variation analysis for microarray and RNA-seq data.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE16965

WGCNA: an R package for weighted correlation network analysis

21 January 2018

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Defining clusters from a hierarchical cluster tree: the Dynamic Tree Cut package for R.

21 January 2018

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A network module-based method for identifying cancer prognostic signatures

21 January 2018

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lumi: a pipeline for processing Illumina microarray

21 January 2018

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Functions of TAp63 and p53 in restraining the development of metastatic cancer.

21 January 2018

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Inferring tumour purity and stromal and immune cell admixture from expression data

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Using GenePattern for gene expression analysis

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12 December 2020

voom: Precision weights unlock linear model analysis tools for RNA-seq read counts

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12 December 2020

Integrative genomic and functional profiling of the pancreatic cancer genome

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The `dnet’ approach promotes emerging research on cancer patient survival

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12 December 2020

Identifiers

DOI

10.1038/NATURE16965

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6 September 2017

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