(Q47630786)

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A novel transgenic rat model for spinocerebellar ataxia type 17 recapitulates neuropathological changes and supplies in vivo imaging biomarkers.

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Europe PubMed Central

4 February 2018

http://europepmc.org/abstract/MED/23699518

A novel transgenic rat model for spinocerebellar ataxia type 17 recapitulates neuropathological changes and supplies in vivo imaging biomarkers (English)

1 reference

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12 May 2020

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spinocerebellar ataxia type 17

1 reference

based on heuristic

inferred from title

Huu Phuc Nguyen

11

1 reference

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12 May 2020

author name string

Alexandra Kelp

1

1 reference

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12 May 2020

Arnulf H Koeppen

2

1 reference

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12 May 2020

Claudia Bauer

5

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12 May 2020

Esteban Portal

6

1 reference

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12 May 2020

Bernd Pichler

8

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12 May 2020

Peter Bauer

9

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12 May 2020

Elisabeth Petrasch-Parwez

3

1 reference

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12 May 2020

Carsten Calaminus

4

1 reference

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12 May 2020

Libo Yu-Taeger

7

1 reference

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12 May 2020

Olaf Riess

10

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12 May 2020

language of work or name

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publication date

1 May 2013

1 reference

Europe PubMed Central

4 February 2018

http://europepmc.org/abstract/MED/23699518

Journal of Neuroscience

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12 May 2020

33

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12 May 2020

21

1 reference

Europe PubMed Central

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12 May 2020

9068-9081

1 reference

Europe PubMed Central

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12 May 2020

A fast polymerase chain reaction-mediated strategy for introducing repeat expansions into CAG-repeat containing genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A neurological disease caused by an expanded CAG trinucleotide repeat in the TATA-binding protein gene: a new polyglutamine disease?

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bioenergetics in Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear accumulation of truncated atrophin-1 fragments in a transgenic mouse model of DRPLA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long glutamine tracts cause nuclear localization of a novel form of huntingtin in medium spiny striatal neurons in HdhQ92 and HdhQ111 knock-in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamine repeats and neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurological abnormalities in a knock-in mouse model of Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different types of repeat expansion in the TATA-binding protein gene are associated with a new form of inherited ataxia

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SCA17, a novel autosomal dominant cerebellar ataxia caused by an expanded polyglutamine in TATA-binding protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CAG repeat expansion in the TATA box-binding protein gene causes autosomal dominant cerebellar ataxia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polyglutamine-expanded ataxin-7 promotes non-cell-autonomous purkinje cell degeneration and displays proteolytic cleavage in ataxic transgenic mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early motor dysfunction and striosomal distribution of huntingtin microaggregates in Huntington's disease knock-in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical features and neuropathology of autosomal dominant spinocerebellar ataxia (SCA17).

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intergenerational instability and marked anticipation in SCA-17

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diffusion tensor imaging detects age-dependent white matter changes in a transgenic mouse model with amyloid deposition

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurobehavioral assessment in the information age.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Huntington disease: volumetric, diffusion-weighted, and magnetization transfer MR imaging of brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regional white matter change in pre-symptomatic Huntington's disease: a diffusion tensor imaging study

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Juvenile Huntington's disease: does a dosage-effect pathogenic mechanism differ from the classical adult disease?

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diffusion-weighted imaging in Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diffusion tensor imaging in presymptomatic and early Huntington's disease: Selective white matter pathology and its relationship to clinical measures.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New strategies in the search for anxiolytics

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polyglutamine neurodegenerative diseases and regulation of transcription: assembling the puzzle

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repeat expansion in spinocerebellar ataxia type 17 alleles of the TATA-box binding protein gene: an evolutionary approach.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1alpha in Huntington's disease neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular and subcellular localization of Huntingtin [corrected] aggregates in the brain of a rat transgenic for Huntington disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative diffusion tensor imaging detects dopaminergic neuronal degeneration in a murine model of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear localization of ataxin-3 is required for the manifestation of symptoms in SCA3: in vivo evidence

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased metabolism in the R6/2 mouse model of Huntington's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spinocerebellar ataxia type 17 (SCA17): oculomotor phenotype and clinical characterization of 15 Italian patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polyglutamine domain modulates the TBP-TFIIB interaction: implications for its normal function and neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

White matter connections reflect changes in voluntary-guided saccades in pre-symptomatic Huntington's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pallidal neuronal discharge in Huntington's disease: support for selective loss of striatal cells originating the indirect pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Longitudinal diffusion tensor imaging in a rat brain glioma model

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Magnetic resonance imaging as an approach towards identifying neuropathological biomarkers for Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NeuroScale, the battery of behavioral tests with novel scoring system for phenotyping of transgenic rat model of tauopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of Phosphodiesterase 10A Increases the Responsiveness of Striatal Projection Neurons to Cortical Stimulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A longitudinal diffusion tensor imaging study in symptomatic Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo evidence for the selective subcortical degeneration in Huntington's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diffusion tensor imaging in a rat model of Parkinson's disease after lesioning of the nigrostriatal tract

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversibility of symptoms in a conditional mouse model of spinocerebellar ataxia type 3

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dysregulation of coordinated neuronal firing patterns in striatum of freely behaving transgenic rats that model Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered white matter microstructure in the corpus callosum in Huntington's disease: implications for cortical "disconnection".

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased diffusivity in the caudate nucleus of presymptomatic huntington disease gene carriers: which explanation?

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regional distribution and clinical correlates of white matter structural damage in Huntington disease: a tract-based spatial statistics study

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A simple composite phenotype scoring system for evaluating mouse models of cerebellar ataxia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A complementary diffusion tensor imaging (DTI)-histological study in a model of Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neuropathology of late-onset Friedreich's ataxia

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential electrophysiological changes in striatal output neurons in Huntington's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic and type 1 cannabinoid receptor imaging of a transgenic rat model in the early phase of Huntington disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotective effects of granulocyte-colony stimulating factor in a novel transgenic mouse model of SCA17.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal expression of TATA box-binding protein containing expanded polyglutamine in knock-in mice reduces chaperone protein response by impairing the function of nuclear factor-Y transcription factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Possibilities and limitations for high resolution small animal MRI on a clinical whole-body 3T scanner.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Motor function and dopamine release measurements in transgenic Huntington's disease model rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generation of a novel rodent model for DYT1 dystonia

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered diffusion tensor imaging measurements in aged transgenic Huntington disease rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PET and MRI reveal early evidence of neurodegeneration in spinocerebellar ataxia type 17.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and characterization of Huntington related pathology: an in vivo DKI imaging study

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficient expansion and dopaminergic differentiation of human fetal ventral midbrain neural stem cells by midbrain morphogens

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Survival and functional restoration of human fetal ventral mesencephalon following transplantation in a rat model of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral administration of the pimelic diphenylamide HDAC inhibitor HDACi 4b is unsuitable for chronic inhibition of HDAC activity in the CNS in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lamotrigine ameliorates seizures and psychiatric comorbidity in a rat model of spontaneous absence epilepsy

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel BACHD transgenic rat exhibits characteristic neuropathological features of Huntington disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Substituted benzamides as ligands for visualization of dopamine receptor binding in the human brain by positron emission tomography

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemistry and structural biology of transcription factor IID (TFIID)

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FELASA recommendations for the health monitoring of mouse, rat, hamster, gerbil, guinea pig and rabbit experimental units. Report of the Federation of European Laboratory Animal Science Associations (FELASA) Working Group on Animal Health accepted b

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A vector for expressing foreign genes in the brains and hearts of transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin

1 reference

https://pubmed.ncbi.nlm.nih.gov/23699518

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.5622-12.2013

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6705027&resulttype=core&format=json

12 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6705027&resulttype=core&format=json

12 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6705027&resulttype=core&format=json

12 May 2020

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