(Q47648895)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29035360%20AND%20SRC:MED&resulttype=core&format=json

7 April 2020

title

EZH2 promotes degradation of stalled replication forks by recruiting MUS81 through histone H3 trimethylation (English)

1 reference

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7 April 2020

10

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7 April 2020

Alan D'Andrea

11

1 reference

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7 April 2020

author name string

Beatrice Rondinelli

1

1 reference

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7 April 2020

Ewa Gogola

2

1 reference

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7 April 2020

Hatice Yücel

3

1 reference

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7 April 2020

Alexandra A Duarte

4

1 reference

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7 April 2020

Marieke van de Ven

5

1 reference

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7 April 2020

Roxanne van der Sluijs

6

1 reference

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7 April 2020

Panagiotis A Konstantinopoulos

7

1 reference

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7 April 2020

Jos Jonkers

8

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7 April 2020

Raphaël Ceccaldi

9

1 reference

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7 April 2020

publication date

16 October 2017

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7 April 2020

1 reference

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7 April 2020

volume

19

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7 April 2020

page(s)

1371-1378

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7 April 2020

issue

11

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https://scigraph.springernature.com/pub.10.1038/ncb3626

7 April 2020

exact match

0 references

cites work

Mechanisms of resistance to therapies targeting BRCA-mutant cancers

1 reference

Replication fork stability confers chemoresistance in BRCA-deficient cells

21 January 2018

1 reference

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

21 January 2018

1 reference

Homologous Recombination Deficiency: Exploiting the Fundamental Vulnerability of Ovarian Cancer

21 January 2018

1 reference

Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11.

21 January 2018

1 reference

53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers

21 January 2018

1 reference

Chromatin replication and epigenome maintenance

21 January 2018

1 reference

Chromatin assembly controls replication fork stability.

21 January 2018

1 reference

Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia

21 January 2018

1 reference

Prolonged Ezh2 Depletion in Glioblastoma Causes a Robust Switch in Cell Fate Resulting in Tumor Progression.

21 January 2018

1 reference

Polycomb group protein-mediated repression of transcription

21 January 2018

1 reference

EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer

21 January 2018

1 reference

Polycomb repressive complex 2 contributes to DNA double-strand break repair

21 January 2018

1 reference

A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage

21 January 2018

1 reference

A model for transmission of the H3K27me3 epigenetic mark

21 January 2018

1 reference

Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair

21 January 2018

1 reference

FANCD2 Maintains Fork Stability in BRCA1/2-Deficient Tumors and Promotes Alternative End-Joining DNA Repair

21 January 2018

1 reference

Integrated genomic analyses of ovarian carcinoma

21 January 2018

1 reference

EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations

21 January 2018

1 reference

21 January 2018

Targeting EZH2 in cancer

1 reference

Maintaining genome stability at the replication fork

21 January 2018

1 reference

Nascent chromatin capture proteomics determines chromatin dynamics during DNA replication and identifies unknown fork components

21 January 2018

1 reference

Polycomb proteins control proliferation and transformation independently of cell cycle checkpoints by regulating DNA replication

21 January 2018

1 reference

Two distinct modes for propagation of histone PTMs across the cell cycle

21 January 2018

1 reference

Human RPA phosphorylation by ATR stimulates DNA synthesis and prevents ssDNA accumulation during DNA-replication stress

21 January 2018

1 reference

Pathways of mammalian replication fork restart.

21 January 2018

1 reference

Preventing replication fork collapse to maintain genome integrity

21 January 2018

1 reference

Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair.

21 January 2018

1 reference

Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer.

21 January 2018

1 reference

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

21 January 2018

1 reference

The structure-specific endonuclease Mus81 contributes to replication restart by generating double-strand DNA breaks

21 January 2018

1 reference

Sae2 promotes DNA damage resistance by removing the Mre11-Rad50-Xrs2 complex from DNA and attenuating Rad53 signaling

21 January 2018

1 reference

Comprehensive molecular portraits of human breast tumours

21 January 2018

1 reference

Selective induction of chemotherapy resistance of mammary tumors in a conditional mouse model for hereditary breast cancer

21 January 2018

1 reference

DNA2 drives processing and restart of reversed replication forks in human cells.

21 January 2018

1 reference

Accumulation of Pax2 transactivation domain interaction protein (PTIP) at sites of DNA breaks via RNF8-dependent pathway is required for cell survival after DNA damage

21 January 2018

1 reference

Integrated genomic characterization of endometrial carcinoma

21 January 2018

1 reference

A rapid and efficient method to purify proteins at replication forks under native conditions.

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29035360

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

DNA replication-dependent nuclear dynamics of the Mre11 complex.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29035360

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Homology-directed dna repair, mitomycin-c resistance, and chromosome stability is restored with correction of a Brca1 mutation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29035360

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCB3626

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29035360%20AND%20SRC:MED&resulttype=core&format=json

7 April 2020

1 reference