(Q47683497)

4 February 2018

title

Social deficits in IRSp53 mutant mice improved by NMDAR and mGluR5 suppression (English)

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4 February 2018

Jaeseung Kang

5

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Min Whan Jung

17

object named as

Min Whan Jung

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4 February 2018

author name string

Woosuk Chung

1

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4 February 2018

Su Yeon Choi

2

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4 February 2018

Eunee Lee

3

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4 February 2018

Haram Park

4

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4 February 2018

Hanwool Park

6

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4 February 2018

Yeonsoo Choi

7

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4 February 2018

Dongsoo Lee

8

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4 February 2018

Sae-Geun Park

9

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4 February 2018

Ryunhee Kim

10

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4 February 2018

Yi Sul Cho

11

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4 February 2018

Jeonghoon Choi

12

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4 February 2018

Myoung-Hwan Kim

13

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4 February 2018

Jong Won Lee

14

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4 February 2018

Seungjoon Lee

15

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4 February 2018

Issac Rhim

16

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4 February 2018

Daesoo Kim

18

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4 February 2018

Yong Chul Bae

19

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4 February 2018

Eunjoon Kim

20

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4 February 2018

language of work or name

English

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publication date

26 January 2015

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4 February 2018

published in

Nature Neuroscience

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4 February 2018

volume

18

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4 February 2018

issue

3

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4 February 2018

page(s)

435-443

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4 February 2018

The genetic landscapes of autism spectrum disorders

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Functional consequences of mutations in postsynaptic scaffolding proteins and relevance to psychiatric disorders.

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Activity-dependent neuronal signalling and autism spectrum disorder

21 January 2018

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IRSp53: crossing the road of membrane and actin dynamics in the formation of membrane protrusions

21 January 2018

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The postsynaptic architecture of excitatory synapses: a more quantitative view

21 January 2018

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Postsynaptic distribution of IRSp53 in spiny excitatory and inhibitory neurons

21 January 2018

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Regulation of dendritic spine morphogenesis by insulin receptor substrate 53, a downstream effector of Rac1 and Cdc42 small GTPases

21 January 2018

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Insulin receptor substrate of 53 kDa links postsynaptic shank to PSD-95.

21 January 2018

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ProSAP/Shank postsynaptic density proteins interact with insulin receptor tyrosine kinase substrate IRSp53

21 January 2018

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Actin in action: the interplay between the actin cytoskeleton and synaptic efficacy

21 January 2018

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Enhanced NMDA receptor-mediated synaptic transmission, enhanced long-term potentiation, and impaired learning and memory in mice lacking IRSp53.

21 January 2018

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The insulin receptor substrate of 53 kDa (IRSp53) limits hippocampal synaptic plasticity

21 January 2018

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Distinct triggering and expression mechanisms underlie LTD of AMPA and NMDA synaptic responses.

21 January 2018

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Automated apparatus for quantitation of social approach behaviors in mice.

21 January 2018

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Activation of NMDA receptors reverses desensitization of mGluR5 in native and recombinant systems

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NMDA receptor trafficking in synaptic plasticity and neuropsychiatric disorders

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Neocortical excitation/inhibition balance in information processing and social dysfunction

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The medial prefrontal cortex and integration in autism

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Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function

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Absence of CNTNAP2 leads to epilepsy, neuronal migration abnormalities, and core autism-related deficits

21 January 2018

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Ultrastructure of synapses in the mammalian brain

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Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function

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Tbr1 haploinsufficiency impairs amygdalar axonal projections and results in cognitive abnormality

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Deletion of glutamate delta-1 receptor in mouse leads to aberrant emotional and social behaviors

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Association study of six candidate genes asymmetrically expressed in the two cerebral hemispheres suggests the involvement of BAIAP2 in autism.

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Rare De Novo and Transmitted Copy-Number Variation in Autistic Spectrum Disorders

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Rare de novo variants associated with autism implicate a large functional network of genes involved in formation and function of synapses

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Case-control study of six genes asymmetrically expressed in the two cerebral hemispheres: association of BAIAP2 with attention-deficit/hyperactivity disorder

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BAIAP2 exhibits association to childhood ADHD especially predominantly inattentive subtype in Chinese Han subjects

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Are NMDA receptor antagonists beneficial in the treatment of schizophrenia?

21 January 2018

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Glutamate and schizophrenia: beyond the dopamine hypothesis

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Attention deficit hyperactivity disorder and N-methyl-D-aspartate (NMDA) dysregulation

21 January 2018

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Social approach and repetitive behavior in eleven inbred mouse strains

21 January 2018

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Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism

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Autism-like behavioral phenotypes in BTBR T+tf/J mice

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Motor and cognitive stereotypies in the BTBR T+tf/J mouse model of autism

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Digging and marble burying in mice: simple methods for in vivo identification of biological impacts.

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In vivo receptor occupancy of mGlu5 receptor antagonists using the novel radioligand [3H]3-methoxy-5-(pyridin-2-ylethynyl)pyridine).

21 January 2018

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Memantine is a clinically well tolerated N-methyl-D-aspartate (NMDA) receptor antagonist--a review of preclinical data

21 January 2018

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Characterization of the Shank family of synaptic proteins. Multiple genes, alternative splicing, and differential expression in brain and development

21 January 2018

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Disruption of dentate gyrus blocks effect of visual input on spatial firing of CA1 neurons

21 January 2018

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Chemical induction of mGluR5- and protein synthesis--dependent long-term depression in hippocampal area CA1.

21 January 2018

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12 December 2020

The insulin receptor tyrosine kinase substrate p58/53 and the insulin receptor are components of CNS synapses

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12 December 2020

Selective abolition of the NMDA component of long-term potentiation in mice lacking mGluR5.

1 reference

12 December 2020

Role of actin in anchoring postsynaptic receptors in cultured hippocampal neurons: differential attachment of NMDA versus AMPA receptors.

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12 December 2020

Regulation of F-actin stability in dendritic spines by glutamate receptors and calcineurin.

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12 December 2020

Memantine: a review of possible uses in child and adolescent psychiatry

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12 December 2020

Dendritic organization in the neurons of the visual and motor cortices of the cat

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12 December 2020

Identifiers

DOI

10.1038/NN.3927

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4 February 2018

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4 February 2018