(Q54782597)

3 June 2018

title

Fragile X syndrome: From protein function to therapy. (English)

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3 June 2018

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1

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3 June 2018

Ben A Oostra

series ordinal

2

object named as

Ben A Oostra

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3 June 2018

language of work or name

English

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publication date

24 September 2013

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3 June 2018

American Journal of Medical Genetics

published in

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3 June 2018

volume

161A

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3 June 2018

issue

11

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3 June 2018

page(s)

2809-2821

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3 June 2018

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

1 reference

Metabotropic glutamate receptor activation regulates fragile x mental retardation protein and FMR1 mRNA localization differentially in dendrites and at synapses

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Localization of FMRP-associated mRNA granules and requirement of microtubules for activity-dependent trafficking in hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Local functions for FMRP in axon growth cone motility and activity-dependent regulation of filopodia and spine synapses

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

FMRP targets distinct mRNA sequence elements to regulate protein expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

FMR1 protein: conserved RNP family domains and selective RNA binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Mutations causing syndromic autism define an axis of synaptic pathophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Fragile X syndrome: causes, diagnosis, mechanisms, and therapeutics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Understanding fragile X syndrome: insights from animal models

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

82-FIP, a novel FMRP (fragile X mental retardation protein) interacting protein, shows a cell cycle-dependent intracellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

The mGluR theory of fragile X mental retardation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

A pilot open label, single dose trial of fenobam in adults with fragile X syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Minocycline promotes dendritic spine maturation and improves behavioural performance in the fragile X mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

FMR1 transcript isoforms: association with polyribosomes; regional and developmental expression in mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Dendritic mRNA: transport, translation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

FMRP involvement in formation of synapses among cultured hippocampal neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

The Drosophila fragile X mental retardation gene regulates sleep need

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Phosphorylation influences the translation state of FMRP-associated polyribosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Identification of small molecules rescuing fragile X syndrome phenotypes in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Phosphorylation of FMRP inhibits association with Dicer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

The fragile X mental retardation protein binds and regulates a novel class of mRNAs containing U rich target sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Prolonged epileptiform discharges induced by altered group I metabotropic glutamate receptor-mediated synaptic responses in hippocampal slices of a fragile X mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Fragile X mental retardation protein has a unique, evolutionarily conserved neuronal function not shared with FXR1P or FXR2P

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Array-based FMR1 sequencing and deletion analysis in patients with a fragile X syndrome-like phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Delayed stabilization of dendritic spines in fragile X mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

The translation of translational control by FMRP: therapeutic targets for FXS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

The nuclear microspherule protein 58 is a novel RNA-binding protein that interacts with fragile X mental retardation protein in polyribosomal mRNPs from neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

The fragile X mental retardation protein is a molecular adaptor between the neurospecific KIF3C kinesin and dendritic RNA granules

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

A point mutation in the FMR-1 gene associated with fragile X mental retardation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Fragile X mental retardation protein control of neuronal mRNA metabolism: Insights into mRNA stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Molecular and cellular aspects of mental retardation in the Fragile X syndrome: from gene mutation/s to spine dysmorphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Rescue of behavioral phenotype and neuronal protrusion morphology in Fmr1 KO mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Generation and characterization of FMR1 knockout zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

The GABAA receptor: a novel target for treatment of fragile X?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Decreased expression of the GABAA receptor in fragile X syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

A direct role for FMRP in activity-dependent dendritic mRNA transport links filopodial-spine morphogenesis to fragile X syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Correction of fragile X syndrome in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Mechanism-based approaches to treating fragile X

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Regulation of synaptic structure and function by FMRP-associated microRNAs miR-125b and miR-132

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Decreased GABA(A) receptor expression in the seizure-prone fragile X mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Taurine regulation of short term synaptic plasticity in fragile X mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Characterization of Fxr1 in Danio rerio; a simple vertebrate model to study costamere development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Expansion of an FMR1 grey-zone allele to a full mutation in two generations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

The fragile X mental retardation protein-RNP granules show an mGluR-dependent localization in the post-synaptic spines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Signaling mechanisms linking neuronal activity to gene expression and plasticity of the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Variation of the CGG repeat at the fragile X site results in genetic instability: Resolution of the Sherman paradox

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Sequence of abnormal dendritic spine development in primary somatosensory cortex of a mouse model of the fragile X mental retardation syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Expression profiling suggests underexpression of the GABA(A) receptor subunit delta in the fragile X knockout mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Chronic administration of AFQ056/Mavoglurant restores social behaviour in Fmr1 knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

FMR1/FXR1 and the miRNA pathway are required for eye and neural crest development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Metabotropic glutamate receptor-mediated long-term depression: molecular mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Therapeutic implications for striatal-enriched protein tyrosine phosphatase (STEP) in neuropsychiatric disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Synaptic regulation of protein synthesis and the fragile X protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Excess phosphoinositide 3-kinase subunit synthesis and activity as a novel therapeutic target in fragile X syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Therapeutic strategies in fragile X syndrome: dysregulated mGluR signaling and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Hippocampal pyramidal cells in adult Fmr1 knockout mice exhibit an immature-appearing profile of dendritic spines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Ablation of Fmrp in adult neural stem cells disrupts hippocampus-dependent learning

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Fragile X syndrome and targeted treatment trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Reversal of disease-related pathologies in the fragile X mouse model by selective activation of GABAB receptors with arbaclofen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Pharmacological treatment of fragile X syndrome with GABAergic drugs in a knockout mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Subcellular mRNA localization in animal cells and why it matters

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Dynamic translational and proteasomal regulation of fragile X mental retardation protein controls mGluR-dependent long-term depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Altered synaptic plasticity in a mouse model of fragile X mental retardation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Dendritic spine and dendritic field characteristics of layer V pyramidal neurons in the visual cortex of fragile-X knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Epigenetic modification of the FMR1 gene in fragile X syndrome is associated with differential response to the mGluR5 antagonist AFQ056.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Role of Pur alpha in targeting mRNA to sites of translation in hippocampal neuronal dendrites

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Kinesin transports RNA: isolation and characterization of an RNA-transporting granule

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Learning and memory deficits consequent to reduction of the fragile X mental retardation protein result from metabotropic glutamate receptor-mediated inhibition of cAMP signaling in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Altered mRNA transport, docking, and protein translation in neurons lacking fragile X mental retardation protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Molecular phenotype of Fragile X syndrome: FMRP, FXRPs, and protein targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Biochemical evidence for the association of fragile X mental retardation protein with brain polyribosomal ribonucleoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Of mice and the fragile X syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Cognitive dysfunction and prefrontal synaptic abnormalities in a mouse model of fragile X syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Evidence that fragile X mental retardation protein is a negative regulator of translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Potential therapeutic interventions for fragile X syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Subregion-specific dendritic spine abnormalities in the hippocampus of Fmr1 KO mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

AFQ056, a new mGluR5 antagonist for treatment of fragile X syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

The fragile X mental retardation protein inhibits translation via interacting with mRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

The HMG-CoA reductase inhibitor lovastatin reverses the learning and attention deficits in a mouse model of neurofibromatosis type 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

CTEP: a novel, potent, long-acting, and orally bioavailable metabotropic glutamate receptor 5 inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Tdrd3 is a novel stress granule-associated protein interacting with the Fragile-X syndrome protein FMRP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Drosophila FMRP participates in the DNA damage response by regulating G2/M cell cycle checkpoint and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

The fragile X protein controls microtubule-associated protein 1B translation and microtubule stability in brain neuron development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Long-term depression: multiple forms and implications for brain function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Pharmacological rescue of synaptic plasticity, courtship behavior, and mushroom body defects in a Drosophila model of fragile X syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Dendritic spine abnormalities in the occipital cortex of C57BL/6 Fmr1 knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Evidence for social anxiety and impaired social cognition in a mouse model of fragile X syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

The C terminus of fragile X mental retardation protein interacts with the multi-domain Ran-binding protein in the microtubule-organising centre

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Chronic pharmacological mGlu5 inhibition corrects fragile X in adult mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

The generation of a conditional Fmr1 knock out mouse model to study Fmrp function in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Behavioral and neuroanatomical characterization of the Fmr1 knockout mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

RNA cargoes associating with FMRP reveal deficits in cellular functioning in Fmr1 null mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Fragile X mental retardation protein controls trailer hitch expression and cleavage furrow formation in Drosophila embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

A boost in microRNAs shapes up the neuron

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Dysregulated metabotropic glutamate receptor-dependent translation of AMPA receptor and postsynaptic density-95 mRNAs at synapses in a mouse model of fragile X syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Reversible inhibition of PSD-95 mRNA translation by miR-125a, FMRP phosphorylation, and mGluR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Three-dimensional structure and stability of the KH domain: molecular insights into the fragile X syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Audiogenic seizures susceptibility in transgenic mice with fragile X syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Audiogenic seizure susceptibility is reduced in fragile X knockout mice after introduction of FMR1 transgenes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

The fragile X syndrome protein represses activity-dependent translation through CYFIP1, a new 4E-BP

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

FMRP phosphorylation reveals an immediate-early signaling pathway triggered by group I mGluR and mediated by PP2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

The unstable repeats--three evolving faces of neurological disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Metabotropic receptor-dependent long-term depression persists in the absence of protein synthesis in the mouse model of fragile X syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Instability of a 550-base pair DNA segment and abnormal methylation in fragile X syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

A decade of molecular studies of fragile X syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Amygdala regulation of fear and emotionality in fragile X syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Hypersensitivity to mGluR5 and ERK1/2 leads to excessive protein synthesis in the hippocampus of a mouse model of fragile X syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Lovastatin corrects excess protein synthesis and prevents epileptogenesis in a mouse model of fragile X syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Increased GABA(B) receptor-mediated signaling reduces the susceptibility of fragile X knockout mice to audiogenic seizures

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Genetic deletion of regulator of G-protein signaling 4 (RGS4) rescues a subset of fragile X related phenotypes in the FMR1 knockout mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

dFMRP and Caprin, translational regulators of synaptic plasticity, control the cell cycle at the Drosophila mid-blastula transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Open-label add-on treatment trial of minocycline in fragile X syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

In vitro and in cellulo evidences for association of the survival of motor neuron complex with the fragile X mental retardation protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Genetic-background modulation of core and variable autistic-like symptoms in Fmr1 knock-out mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Which comes first in fragile X syndrome, dendritic spine dysgenesis or defects in circuit plasticity?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

The structure of the N-terminal domain of the fragile X mental retardation protein: a platform for protein-protein interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Enriched environment promotes behavioral and morphological recovery in a mouse model for the fragile X syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Metabotropic glutamate receptors and fragile x mental retardation protein: partners in translational regulation at the synapse

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Altered auditory processing in a mouse model of fragile X syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Minocycline treatment reverses ultrasonic vocalization production deficit in a mouse model of Fragile X Syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

The Drosophila gene RanBPM functions in the mushroom body to regulate larval behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

CYFIP/Sra-1 controls neuronal connectivity in Drosophila and links the Rac1 GTPase pathway to the fragile X protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Fragile X mental retardation protein regulates the levels of scaffold proteins and glutamate receptors in postsynaptic densities

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Dysregulation of mTOR signaling in fragile X syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Further segregation analysis of the fragile X syndrome with special reference to transmitting males

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Rapid spine delivery and redistribution of AMPA receptors after synaptic NMDA receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

The protein product of the fragile X gene, FMR1, has characteristics of an RNA-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Specific sequences in the fragile X syndrome protein FMR1 and the FXR proteins mediate their binding to 60S ribosomal subunits and the interactions among them

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Alternative splicing of exon 14 determines nuclear or cytoplasmic localisation of fmr1 protein isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

A study of the ultrastructure of fragile-X-related proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Altered anxiety-related and social behaviors in the Fmr1 knockout mouse model of fragile X syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Modifying behavioral phenotypes in Fmr1KO mice: genetic background differences reveal autistic-like responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Fragile X mental retardation protein is associated with translating polyribosomes in neuronal cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Compartmentalized synthesis and degradation of proteins in neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

DNA methylation represses FMR-1 transcription in fragile X syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Oligomerization properties of fragile-X mental-retardation protein (FMRP) and the fragile-X-related proteins FXR1P and FXR2P

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

The targeting and functions of miRNA-383 are mediated by FMRP during spermatogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Altered maturation of the primary somatosensory cortex in a mouse model of fragile X syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Multiple autism-linked genes mediate synapse elimination via proteasomal degradation of a synaptic scaffold PSD-95

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Expression of three zebrafish orthologs of human FMR1-related genes and their phylogenetic relationships.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Contribution of mGluR and Fmr1 functional pathways to neurite morphogenesis, craniofacial development and fragile X syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Side effects of minocycline treatment in patients with fragile X syndrome and exploration of outcome measures

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Fragile X mental retardation syndrome: structure of the KH1-KH2 domains of fragile X mental retardation protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Structure and function of KH domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Characterisation of Fmrp in zebrafish: evolutionary dynamics of the fmr1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Characterization and localization of the FMR-1 gene product associated with fragile X syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Alternative splicing in the fragile X gene FMR1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Differential compartmentalization and distinct functions of GABAB receptor variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Characterization of dFMR1, a Drosophila melanogaster homolog of the fragile X mental retardation protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Fragile X syndrome: from targets to treatments

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Association of FMRP with ribosomal precursor particles in the nucleolus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Tissue and developmental regulation of fragile X mental retardation 1 exon 12 and 15 isoforms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Suppression of two major Fragile X Syndrome mouse model phenotypes by the mGluR5 antagonist MPEP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

The fragile X syndrome protein FMRP associates with BC1 RNA and regulates the translation of specific mRNAs at synapses

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Fragile X mental retardation protein (FMRP) binds specifically to the brain cytoplasmic RNAs BC1/BC200 via a novel RNA-binding motif.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

mRNPs, polysomes or granules: FMRP in neuronal protein synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

A new function for the fragile X mental retardation protein in regulation of PSD-95 mRNA stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Drosophila fragile X-related gene regulates the MAP1B homolog Futsch to control synaptic structure and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Fragile X mental retardation protein FMRP and the RNA export factor NXF2 associate with and destabilize Nxf1 mRNA in neuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

Signals, synapses, and synthesis: how new proteins control plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.A.36241

21 January 2018

Identifiers

DOI

10.1002/AJMG.A.36241

1 reference

3 June 2018

PubMed ID

24115651

1 reference

3 June 2018