(Q47716673)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28967903%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

title

Loss of protein phosphatase 2A regulatory subunit B56δ promotes spontaneous tumorigenesis in vivo (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28967903%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28967903%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Anna Sablina

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28967903%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

author name string

C Lambrecht

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28967903%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

L Libbrecht

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28967903%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

X Sagaert

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28967903%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

P Pauwels

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28967903%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Y Hoorne

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28967903%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

J Crowther

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28967903%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

J V Louis

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28967903%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

W Sents

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28967903%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

language of work or name

English

0 references

publication date

2 October 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28967903%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28967903%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

volume

37

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28967903%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28967903%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

page(s)

544-552

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28967903%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/onc.2017.350

31 March 2020

exact match

0 references

cites work

PP2A: the expected tumor suppressor

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

Creation of human tumour cells with defined genetic elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

Enumeration of the simian virus 40 early region elements necessary for human cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

Identification of specific PP2A complexes involved in human cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

Identification of PP2A complexes and pathways involved in cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

Circumventing cellular control of PP2A by methylation promotes transformation in an Akt-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

The tumor suppressor PP2A Abeta regulates the RalA GTPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

p27kip1 protein levels reflect a nexus of oncogenic signaling during cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

Protein phosphatase 2A: a target for anticancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

All roads lead to PP2A: exploiting the therapeutic potential of this phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

Alterations of the PPP2R1B gene in human lung and colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

Recurrent PPP2R1A Mutations in Uterine Cancer Act through a Dominant-Negative Mechanism to Promote Malignant Cell Growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

Human cancer-associated mutations in the Aα subunit of protein phosphatase 2A increase lung cancer incidence in Aα knock-in and knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

Evaluation of PPP2R2A as a prostate cancer susceptibility gene: a comprehensive germline and somatic study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

B56γ tumor-associated mutations provide new mechanisms for B56γ-PP2A tumor suppressor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

PPP2R2C loss promotes castration-resistance and is associated with increased prostate cancer-specific mortality

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

Downregulation of PPP2R5E is a common event in acute myeloid leukemia that affects the oncogenic potential of leukemic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

Protein Phosphatase 2A as a Therapeutic Target in Acute Myeloid Leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

Cancerous inhibitor of protein phosphatase 2A, an emerging human oncoprotein and a potential cancer therapy target.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

α4 is highly expressed in carcinogen-transformed human cells and primary human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

PME-1 protects extracellular signal-regulated kinase pathway activity from protein phosphatase 2A-mediated inactivation in human malignant glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

Mice lacking phosphatase PP2A subunit PR61/B'delta (Ppp2r5d) develop spatially restricted tauopathy by deregulation of CDK5 and GSK3beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

Hepatocellular Carcinoma From Epidemiology to Prevention: Translating Knowledge into Practice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

Regulation of beta-catenin signaling by the B56 subunit of protein phosphatase 2A

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

B56-containing PP2A dephosphorylate ERK and their activity is controlled by the early gene IEX-1 and ERK

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

PP2A regulatory subunit PP2A-B' counteracts S6K phosphorylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

Molecular profiling of liver tumors: classification and clinical translation for decision making

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

New targets of beta-catenin signaling in the liver are involved in the glutamine metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

iRegulon: from a gene list to a gene regulatory network using large motif and track collections

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

Phosphorylation by Cdk2 is required for Myc to repress Ras-induced senescence in cotransformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

MYC-dependent regulation and prognostic role of CIP2A in gastric cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

Central role of c-Myc during malignant conversion in human hepatocarcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

Regulation of c-Myc Protein Abundance by a Protein Phosphatase 2A-Glycogen Synthase Kinase 3β-Negative Feedback Pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

Protein phosphatase 2A regulatory subunit B56alpha associates with c-myc and negatively regulates c-myc accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

Identification of c-MYC as a target of the APC pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

A B56gamma mutation in lung cancer disrupts the p53-dependent tumor-suppressor function of protein phosphatase 2A

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

The B56γ3 regulatory subunit-containing protein phosphatase 2A outcompetes Akt to regulate p27KIP1 subcellular localization by selectively dephosphorylating phospho-Thr157 of p27KIP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

PPP2R5C Couples Hepatic Glucose and Lipid Homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

Ser70 phosphorylation of Bcl-2 by selective tyrosine nitration of PP2A-B56δ stabilizes its antiapoptotic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

Upregulation of the oncoprotein SET determines poor clinical outcomes in hepatocellular carcinoma and shows therapeutic potential.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

CIP2A is highly expressed in hepatocellular carcinoma and predicts poor prognosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

Targeting c-MYC by antagonizing PP2A inhibitors in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

CIP2A inhibits PP2A in human malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

Consequences of widespread deregulation of the c-myc gene in transgenic mice: multiple neoplasms and normal development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

Cutadapt removes adapter sequences from high-throughput sequencing reads

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

TopHat: discovering splice junctions with RNA-Seq

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

The Sequence Alignment/Map format and SAMtools

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

BEDTools: a flexible suite of utilities for comparing genomic features

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

Genomic organisation, chromosomal localisation tissue distribution and developmental regulation of the PR61/B' regulatory subunits of protein phosphatase 2A in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

Cancer-associated PP2A Aalpha subunits induce functional haploinsufficiency and tumorigenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

Low frequency of alterations of the alpha (PPP2R1A) and beta (PPP2R1B) isoforms of the subunit A of the serine-threonine phosphatase 2A in human neoplasms

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

Mutation of PPP2R1A: a new clue in unveiling the pathogenesis of uterine serous carcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

PME-1 modulates protein phosphatase 2A activity to promote the malignant phenotype of endometrial cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

Lymphomas and leukemias in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

The protein phosphatase 2A B56γ regulatory subunit is required for heart development

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.350

Heterozygous Rb-1 delta 20/+mice are predisposed to tumors of the pituitary gland with a nearly complete penetrance

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28967903

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

PP2A Inactivation Mediated by PPP2R4 Haploinsufficiency Promotes Cancer Development.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28967903

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2017.350

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28967903%20AND%20SRC:MED&resulttype=core&format=json

release_s66rmm7tqrdijk6lyubqnbod3i

31 March 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/s66rmm7tqrdijk6lyubqnbod3i

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference