(Q47748385)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28945249%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

title

Mechanism and regulation of the Lys6-selective deubiquitinase USP30 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28945249%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28945249%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

David Komander

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28945249%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

author name string

Christina Gladkova

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28945249%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Alexander F Schubert

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28945249%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Martin A Michel

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28945249%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Sarah Maslen

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28945249%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

publication date

25 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28945249%20AND%20SRC:MED&resulttype=core&format=json

Nature Structural & Molecular Biology

31 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28945249%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

volume

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28945249%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28945249%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

page(s)

920-930

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28945249%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

31 March 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5757785/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling

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Ubiquitin S65 phosphorylation engenders a pH-sensitive conformational switch.

16 June 2018

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Mechanisms of Deubiquitinase Specificity and Regulation.

16 June 2018

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Deciphering the Molecular Signals of PINK1/Parkin Mitophagy.

16 June 2018

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The increasing complexity of the ubiquitin code

16 June 2018

1 reference

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Mechanisms of mitophagy: PINK1, Parkin, USP30 and beyond.

16 June 2018

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Diffraction-geometry refinement in the DIALS framework

16 June 2018

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16 June 2018

Ubiquitin modifications

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The missing links to link ubiquitin: Methods for the enzymatic production of polyubiquitin chains

16 June 2018

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The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy

16 June 2018

1 reference

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The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

16 June 2018

1 reference

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A Ubl/ubiquitin switch in the activation of Parkin

16 June 2018

1 reference

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Endogenous Parkin Preserves Dopaminergic Substantia Nigral Neurons following Mitochondrial DNA Mutagenic Stress

16 June 2018

1 reference

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Mechanism of phospho-ubiquitin-induced PARKIN activation

16 June 2018

1 reference

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Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation.

16 June 2018

1 reference

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Quantitative Proteomic Atlas of Ubiquitination and Acetylation in the DNA Damage Response.

16 June 2018

1 reference

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Defining roles of PARKIN and ubiquitin phosphorylation by PINK1 in mitochondrial quality control using a ubiquitin replacement strategy.

16 June 2018

1 reference

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Deubiquitinating enzymes regulate PARK2-mediated mitophagy

16 June 2018

1 reference

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Phosphorylated ubiquitin chain is the genuine Parkin receptor.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

USP30 deubiquitylates mitochondrial Parkin substrates and restricts apoptotic cell death

16 June 2018

1 reference

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USP30 and parkin homeostatically regulate atypical ubiquitin chains on mitochondria

16 June 2018

1 reference

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The roles of PINK1, parkin, and mitochondrial fidelity in Parkinson's disease

16 June 2018

1 reference

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Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysis

16 June 2018

1 reference

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PINK1 and Parkin – mitochondrial interplay between phosphorylation and ubiquitylation in Parkinson's disease

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

Quantitative proteomics reveal a feedforward mechanism for mitochondrial PARKIN translocation and ubiquitin chain synthesis.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

USP8 regulates mitophagy by removing K6-linked ubiquitin conjugates from parkin

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

Conformation-independent structural comparison of macromolecules with ProSMART

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

Screening of DUB activity and specificity by MALDI-TOF mass spectrometry

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

The deubiquitinase USP15 antagonizes Parkin-mediated mitochondrial ubiquitination and mitophagy

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

Ubiquitin is phosphorylated by PINK1 to activate parkin

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

A small natural molecule promotes mitochondrial fusion through inhibition of the deubiquitinase USP30

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

Deubiquitylases from genes to organism

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

Assembly, analysis and architecture of atypical ubiquitin chains

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

On Terminal Alkynes That Can React with Active-Site Cysteine Nucleophiles in Proteases

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

Systematic survey of deubiquitinase localization identifies USP21 as a regulator of centrosome- and microtubule-associated functions

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

Engineering and structural characterization of a linear polyubiquitin-specific antibody

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

What genetics tells us about the causes and mechanisms of Parkinson's disease

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

Systematic and quantitative assessment of the ubiquitin-modified proteome

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

The Phenix software for automated determination of macromolecular structures

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

REFMAC5 for the refinement of macromolecular crystal structures

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

Polyubiquitin binding and cross-reactivity in the USP domain deubiquitinase USP21

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

Biochemical and Structural Studies of a HECT-like Ubiquitin Ligase from Escherichia coli O157:H7

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

K11-linked polyubiquitination in cell cycle control revealed by a K11 linkage-specific antibody

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

Features and development of Coot

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

PINK1 is selectively stabilized on impaired mitochondria to activate Parkin

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

Dissection of USP catalytic domains reveals five common insertion points

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

Phasercrystallographic software

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

The structure of the CYLD USP domain explains its specificity for Lys63-linked polyubiquitin and reveals a B box module

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

Regulation of mitochondrial morphology by USP30, a deubiquitinating enzyme present in the mitochondrial outer membrane

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

A versatile ligation-independent cloning method suitable for high-throughput expression screening applications

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

Scaling and assessment of data quality

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

Derivitization of the C-terminus of ubiquitin and ubiquitin-like proteins using intein chemistry: methods and uses

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

A general method of in vitro preparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

Structure of ubiquitin refined at 1.8 A resolution

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

Structures of CYLD USP with Met1- or Lys63-linked diubiquitin reveal mechanisms for dual specificity.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5757785

The Differential Modulation of USP Activity by Internal Regulatory Domains, Interactors and Eight Ubiquitin Chain Types

14 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNSMB.3475

Structural basis of ubiquitin recognition by the deubiquitinating protease USP2

31 March 2020

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNSMB.3475

Quantitative proteomic analysis by accurate mass retention time pairs

31 March 2020

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNSMB.3475

31 March 2020

Identifiers

DOI

10.1038/NSMB.3475

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28945249%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28945249%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

PubMed publication ID

28945249

1 reference