(Q47753241)

5 February 2018

title

PDK1 decreases TACE-mediated α-secretase activity and promotes disease progression in prion and Alzheimer's diseases (English)

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5 February 2018

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10

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5 February 2018

Mathéa Pietri

1

object named as

Mathéa Pietri

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5 February 2018

Odile Kellermann

12

object named as

Odile Kellermann

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5 February 2018

Jean-Marie Launay

11

object named as

Jean-Marie Launay

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5 February 2018

author name string

Caroline Dakowski

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5 February 2018

Samia Hannaoui

3

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5 February 2018

Aurélie Alleaume-Butaux

4

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5 February 2018

Julia Hernandez-Rapp

5

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5 February 2018

Audrey Ragagnin

6

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5 February 2018

Sophie Mouillet-Richard

7

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5 February 2018

Stéphane Haik

8

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5 February 2018

Yannick Bailly

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5 February 2018

Benoit Schneider

13

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5 February 2018

language of work or name

English

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publication date

18 August 2013

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5 February 2018

published in

Nature Medicine

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5 February 2018

volume

19

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5 February 2018

issue

9

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5 February 2018

page(s)

1124-1131

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5 February 2018

https://scigraph.springernature.com/pub.10.1038/nm.3302

exact match

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cites work

The prion's elusive reason for being

1 reference

Proteolytic processing of Alzheimer's β-amyloid precursor protein

21 January 2018

1 reference

The secretases: enzymes with therapeutic potential in Alzheimer disease

21 January 2018

1 reference

Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein E.

21 January 2018

1 reference

Memory-enhancing effects of secreted forms of the beta-amyloid precursor protein in normal and amnestic mice.

21 January 2018

1 reference

A naturally occurring C-terminal fragment of the prion protein (PrP) delays disease and acts as a dominant-negative inhibitor of PrPSc formation.

21 January 2018

1 reference

The ADAM metalloproteinases

21 January 2018

1 reference

ADAM-17: the enzyme that does it all.

21 January 2018

1 reference

Hyaluronic acid induces survival and proliferation of human myeloma cells through an interleukin-6-mediated pathway involving the phosphorylation of retinoblastoma protein

21 January 2018

1 reference

Evidence that tumor necrosis factor alpha converting enzyme is involved in regulated alpha-secretase cleavage of the Alzheimer amyloid protein precursor

21 January 2018

1 reference

Calpain-dependent endoproteolytic cleavage of PrPSc modulates scrapie prion propagation

21 January 2018

1 reference

Tumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACE

21 January 2018

1 reference

Regulation of mature ADAM17 by redox agents for L-selectin shedding

21 January 2018

1 reference

Cellular prion protein coupling to TACE-dependent TNF-alpha shedding controls neurotransmitter catabolism in neuronal cells

21 January 2018

1 reference

Regulation by neurotransmitter receptors of serotonergic or catecholaminergic neuronal cell differentiation.

21 January 2018

1 reference

Prions impair bioaminergic functions through serotonin- or catecholamine-derived neurotoxins in neuronal cells.

21 January 2018

1 reference

Prion strain- and species-dependent effects of antiprion molecules in primary neuronal cultures

21 January 2018

1 reference

TNF receptor subtype signalling: differences and cellular consequences

21 January 2018

1 reference

Signal transduction through prion protein

21 January 2018

1 reference

Phosphorylation of TNF-alpha converting enzyme by gastrin-releasing peptide induces amphiregulin release and EGF receptor activation.

21 January 2018

1 reference

Pathogenic prions deviate PrP(C) signaling in neuronal cells and impair A-beta clearance

21 January 2018

1 reference

Critical role of PI3K signaling for NF-kappaB-dependent survival in a subset of activated B-cell-like diffuse large B-cell lymphoma cells.

21 January 2018

1 reference

ADAMs family members as amyloid precursor protein alpha-secretases

21 January 2018

1 reference

Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers

21 January 2018

1 reference

Prion protein in Alzheimer's pathogenesis: a hot and controversial issue

21 January 2018

1 reference

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

21 January 2018

1 reference

Small-animal PET imaging of amyloid-beta plaques with [11C]PiB and its multi-modal validation in an APP/PS1 mouse model of Alzheimer's disease

21 January 2018

1 reference

Age and gene overexpression interact to abolish nesting behavior in Tg2576 amyloid precursor protein (APP) mice

21 January 2018

1 reference

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

21 January 2018

1 reference

Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation.

21 January 2018

1 reference

Prion protein recruits its neuronal receptor NCAM to lipid rafts to activate p59fyn and to enhance neurite outgrowth.

21 January 2018

1 reference

The two faces of protein misfolding: gain- and loss-of-function in neurodegenerative diseases

21 January 2018

1 reference

Overstimulation of PrPC signaling pathways by prion peptide 106-126 causes oxidative injury of bioaminergic neuronal cells

21 January 2018

1 reference

Prion-associated increases in Src-family kinases

21 January 2018

1 reference

Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons

21 January 2018

1 reference

The complex PrP(c)-Fyn couples human oligomeric Aβ with pathological tau changes in Alzheimer's disease

21 January 2018

1 reference

Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis.

21 January 2018

1 reference

Tumor necrosis factor death receptor signaling cascade is required for amyloid-beta protein-induced neuron death.

21 January 2018

1 reference

Deletion of tumor necrosis factor death receptor inhibits amyloid beta generation and prevents learning and memory deficits in Alzheimer's mice

21 January 2018

1 reference

Immunocytochemical appearance of cytokines, prostaglandin E2 and lipocortin-1 in the CNS during the incubation period of murine scrapie correlates with progressive PrP accumulations.

21 January 2018

1 reference

The influence of systemic inflammation on inflammation in the brain: implications for chronic neurodegenerative disease

21 January 2018

1 reference

Systemic inflammation and disease progression in Alzheimer disease

21 January 2018

1 reference

Inflammatory markers in population studies of aging

21 January 2018

1 reference

Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease

21 January 2018

1 reference

Early dysfunction of central 5-HT system in a murine model of bovine spongiform encephalopathy.

21 January 2018

1 reference

miR-16 targets the serotonin transporter: a new facet for adaptive responses to antidepressants

21 January 2018

1 reference

Simvastatin treatment prolongs the survival of scrapie-infected mice

21 January 2018

1 reference

ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models

21 January 2018

1 reference

Isolation and culture of adult neurons and neurospheres

21 January 2018

1 reference

Neuritogenesis: the prion protein controls β1 integrin signaling activity.

21 January 2018

1 reference

Automated quantitative analysis (AQUA) of in situ protein expression, antibody concentration, and prognosis

21 January 2018

1 reference

Prion protein and neuronal differentiation: quantitative analysis of prnp gene expression in a murine inducible neuroectodermal progenitor.

21 January 2018

1 reference

Prion protein (PrPc) immunocytochemistry and expression of the green fluorescent protein reporter gene under control of the bovine PrP gene promoter in the mouse brain

21 January 2018

1 reference

BAX contributes to Doppel-induced apoptosis of prion-protein-deficient Purkinje cells

21 January 2018

1 reference

Co-purification and direct interaction of Ras with caveolin, an integral membrane protein of caveolae microdomains. Detergent-free purification of caveolae microdomains

21 January 2018

1 reference

ERK-mediated phosphorylation of Thr735 in TNFalpha-converting enzyme and its potential role in TACE protein trafficking

21 January 2018

1 reference

Immuno-localization of the insulin regulatable glucose transporter in brown adipose tissue of the rat

21 January 2018

1 reference

Study of the PDK1/AKT signaling pathway using selective PDK1 inhibitors, HCS, and enhanced biochemical assays

21 January 2018

1 reference

Manipulation of PrPres production in scrapie-infected neuroblastoma cells

21 January 2018

1 reference

Proliferative activity in the frog brain: a PCNA-immunohistochemistry analysis.

21 January 2018

1 reference

Expression of a developmental stage-specific antigen by neuronal precursor cells of human fetal cerebellum.

21 January 2018

1 reference

Beta-amyloid peptide variants in brains and cerebrospinal fluid from amyloid precursor protein (APP) transgenic mice: comparison with human Alzheimer amyloid

21 January 2018

1 reference

Stable-isotope dilution LC–MS for quantitative biomarker analysis

21 January 2018

1 reference

Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease.

21 January 2018

1 reference

12 December 2020

Induction of cytokines in glial cells surrounding cortical beta-amyloid plaques in transgenic Tg2576 mice with Alzheimer pathology

1 reference

12 December 2020

Levels of alpha- and beta-secretase cleaved amyloid precursor protein in the cerebrospinal fluid of Alzheimer's disease patients

1 reference

12 December 2020

Plasma membrane microdomains regulate TACE-dependent TNFR1 shedding in human endothelial cells

1 reference

12 December 2020

A new method of preparing gold probes for multiple-labeling cytochemistry.

1 reference

12 December 2020

The disintegrins ADAM10 and TACE contribute to the constitutive and phorbol ester-regulated normal cleavage of the cellular prion protein

1 reference

12 December 2020

Unexpectedly strong binding of a large metal ion (Bi3+) to human serum transferrin

1 reference

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NM.3302

1 reference

5 February 2018

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5 February 2018