(Q47770075)

English

Safety and efficacy of cognitive training plus epigallocatechin-3-gallate in young adults with Down's syndrome (TESDAD): a double-blind, randomised, placebo-controlled, phase 2 trial.

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13 March 2020

Safety and efficacy of cognitive training plus epigallocatechin-3-gallate in young adults with Down's syndrome (TESDAD): a double-blind, randomised, placebo-controlled, phase 2 trial (English)

1 reference

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13 March 2020

phase II clinical trial

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13 March 2020

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13 March 2020

Mara Dierssen Sotos

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13 March 2020

Rafael de la Torre

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13 March 2020

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13 March 2020

Montserrat Fitó

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Montserrat Fitó

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13 March 2020

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Susana de Sola

2

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13 March 2020

Gimena Hernandez

3

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13 March 2020

Magí Farré

4

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13 March 2020

Jesus Pujol

5

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13 March 2020

Joan Rodriguez

6

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13 March 2020

Josep María Espadaler

7

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13 March 2020

Aida Cuenca-Royo

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13 March 2020

Alessandro Principe

10

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13 March 2020

Silvina Catuara-Solarz

13

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13 March 2020

Gonzalo Sanchez-Benavides

14

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13 March 2020

Henri Bléhaut

15

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13 March 2020

Iván Dueñas-Espín

16

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13 March 2020

Laura Del Hoyo

17

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13 March 2020

Bessy Benejam

18

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13 March 2020

Laura Blanco-Hinojo

19

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13 March 2020

Sebastiá Videla

20

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13 March 2020

Jean Maurice Delabar

22

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13 March 2020

TESDAD study group

24

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13 March 2020

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1 July 2016

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13 March 2020

Lancet Neurology

1 reference

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13 March 2020

15

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13 March 2020

801-810

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13 March 2020

8

1 reference

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13 March 2020

Therapeutic approaches in the improvement of cognitive performance in Down syndrome: past, present, and future

1 reference

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Down syndrome: the brain in trisomic mode.

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Individual and environmental characteristics associated with cognitive development in Down syndrome: a longitudinal study.

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A longitudinal study of children with Down syndrome who experienced early intervention programming

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The mechanisms of action of flavonoids in the brain: Direct versus indirect effects.

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Pharmacokinetics of (-)-epigallocatechin-3-gallate in conscious and freely moving rats and its brain regional distribution.

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Epigallocatechin-3-gallate, a DYRK1A inhibitor, rescues cognitive deficits in Down syndrome mouse models and in humans

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Environmental enrichment rescues DYRK1A activity and hippocampal adult neurogenesis in TgDyrk1A.

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A new cognitive evaluation battery for Down syndrome and its relevance for clinical trials

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Anomalous brain functional connectivity contributing to poor adaptive behavior in Down syndrome.

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Novel Epigenetic Regulation of Alpha-Synuclein Expression in Down Syndrome

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Green tea EGCG plus fish oil omega-3 dietary supplements rescue mitochondrial dysfunctions and are safe in a Down's syndrome child.

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Identifiers

10.1016/S1474-4422(16)30034-5

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