(Q47770267)

5 February 2018

review article

1 reference

title

Radiosensitivity and oxidative signalling in ataxia telangiectasia: an update. (English)

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5 February 2018

main subject

ataxia telangiectasia

1 reference

Lavin MF

1

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5 February 2018

publication date

1 May 1998

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5 February 2018

Radiotherapy and Oncology

published in

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5 February 2018

volume

47

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5 February 2018

page(s)

113-123

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5 February 2018

issue

2

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5 February 2018

The Klaas Breur Lecture. Radiation, hypoxia and genetic stimulation: implications for future therapies

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7 January 2021

p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts

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7 January 2021

DNA repair mutants defining G2 checkpoint pathways in Schizosaccharomyces pombe

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7 January 2021

Accumulation of wild-type p53 protein upon gamma-irradiation induces a G2 arrest-dependent immunoglobulin kappa light chain gene expression.

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7 January 2021

The DNA-activated protein kinase -- DNA-PK

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7 January 2021

High frequencies of inversions and translocations of chromosomes 7 and 14 in ataxia telangiectasia

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7 January 2021

Atm-deficient mice: a paradigm of ataxia telangiectasia

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7 January 2021

Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation

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7 January 2021

Effect of caffeine on gamma-ray-induced G2 delay in ataxia telangiectasia

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7 January 2021

Radiosensitivity in ataxia-telangiectasia: anomalies in radiation-induced cell cycle delay

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7 January 2021

Defect in multiple cell cycle checkpoints in ataxia-telangiectasia postirradiation

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7 January 2021

Fibroblasts from ataxia telangiectasia (AT) and AT heterozygotes show an enhanced level of residual DNA double-strand breaks after low dose-rate gamma-irradiation as assayed by pulsed field gel electrophoresis

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7 January 2021

The p53 gene as a modifier of intrinsic radiosensitivity: implications for radiotherapy

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7 January 2021

The ataxia-telangiectasia gene product, a constitutively expressed nuclear protein that is not up-regulated following genome damage

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7 January 2021

Mutations revealed by sequencing the 5' half of the gene for ataxia telangiectasia.

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7 January 2021

Phosphoinositide kinases

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7 January 2021

A tightly associated serine/threonine protein kinase regulates phosphoinositide 3-kinase activity

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7 January 2021

The product of the ATM gene is a 370-kDa nuclear phosphoprotein

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7 January 2021

Identification of ataxia telangiectasia heterozygotes, a cancer prone population

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7 January 2021

Heterogeneity in ataxia-telangiectasia: classical phenotype associated with intermediate cellular radiosensitivity.

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7 January 2021

cDNA cloning and gene mapping of a candidate human cell cycle checkpoint protein

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7 January 2021

Thymocyte apoptosis induced by p53-dependent and independent pathways.

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7 January 2021

The effect of bleomycin on DNA synthesis in ataxia telangiectasia lymphoid cells

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https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Rejoining of DNA double-strand breaks in human fibroblasts and its impairment in one ataxia telangiectasia and two Fanconi strains

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Rejoining of double strand breaks in normal human and ataxia-telangiectasia fibroblasts after exposure to 60Co gamma-rays, 241Am alpha-particles or bleomycin

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

On the nature of a defect in cells from individuals with ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Ataxia telangiectasia. Evaluation of radiosensitivity in cultured skin fibroblasts as a diagnostic test

1 reference

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7 January 2021

The rate of DNA synthesis in normal human and ataxia telangiectasia cells after exposure to X-irradiation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

NF-kappa B activation by ultraviolet light not dependent on a nuclear signal.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Unusual levels of (ADP-ribose)n and DNA synthesis in ataxia telangiectasia cells following gamma-ray irradiation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Pleiotropic defects in ataxia-telangiectasia protein-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Ataxia telangiectasia with granulocytopenia

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Dose-rate effect on induction and repair rate of radiation-induced DNA double-strand breaks in a normal and an ataxia telangiectasia human fibroblast cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Hypersensitivity of ataxia telangiectasia fibroblasts to ionizing radiation is associated with a repair deficiency of DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Normal repair of DNA single-strand breaks in patients with ataxia telangiectasia

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Localization of an ataxia-telangiectasia gene to chromosome 11q22-23.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Predominance of null mutations in ataxia-telangiectasia.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Ataxia-telangiectasia: founder effect among north African Jews

1 reference

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7 January 2021

Ataxia telangiectasia. Neoplasia, untoward response to x-irradiation, and tuberous sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Protein kinases and DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

The mei-41 gene of D. melanogaster is a structural and functional homolog of the human ataxia telangiectasia gene

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Checkpoints: controls that ensure the order of cell cycle events

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Cancer in ataxia-telangiectasia patients

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7 January 2021

Isolation of cDNA clones encoding T cell-specific membrane-associated proteins

1 reference

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7 January 2021

Iron-sulfur clusters and oxidant stress responses

1 reference

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7 January 2021

Homology between IRE-BP, a regulatory RNA-binding protein, aconitase, and isopropylmalate isomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Activation of SoxR-dependent transcription in vitro by noncatalytic or NifS-mediated assembly of [2Fe-2S] clusters into apo-SoxR.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

In vitro chromosomal radiosensitivity in "chromosomal breakage syndromes"

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Effect of ionizing radiation on DNA synthesis in ataxia telangiectasia cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

When is a lipid kinase not a lipid kinase? When it is a protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Cancer predisposition. Ataxia-telangiectasia at the crossroads

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

The rad3+ gene of Schizosaccharomyces pombe is involved in multiple checkpoint functions and in DNA repair

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Correction of radiation sensitivity in ataxia telangiectasia cells by a truncated I kappa B-alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

The regulation of AP-1 activity by mitogen-activated protein kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Transcriptional control by protein phosphorylation: signal transmission from the cell surface to the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

The Atr and Atm protein kinases associate with different sites along meiotically pairing chromosomes.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Activation of the c-Abl tyrosine kinase in the stress response to DNA-damaging agents

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Association of a polynuclear iron-sulfur center with a mutant FNR protein enhances DNA binding

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Relationship of the ataxia-telangiectasia protein ATM to phosphoinositide 3-kinase

1 reference

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7 January 2021

Ataxia-telangiectasia: a multifaceted genetic disorder associated with defective signal transduction

1 reference

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7 January 2021

The genetic defect in ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

DNA binding and dimerization of the Fe-S-containing FNR protein from Escherichia coli are regulated by oxygen.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

p53 mutations increase resistance to ionizing radiation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

The response of ataxia telangiectasia cells to bleomycin

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Feedback control of mitosis in budding yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

The ionizing radiation-induced replication protein A phosphorylation response differs between ataxia telangiectasia and normal human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

p53 is required for radiation-induced apoptosis in mouse thymocytes

1 reference

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7 January 2021

Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?

1 reference

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7 January 2021

Oxidative stress induces activation of a cytosolic protein responsible for control of iron uptake.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Radiation reaction in ataxia telangiectasia

1 reference

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7 January 2021

Fragments of ATM which have dominant-negative or complementing activity

1 reference

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7 January 2021

DNA replication and repair in ataxia telangiectasia cells exposed to bleomycin

1 reference

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7 January 2021

Creative blocks: cell-cycle checkpoints and feedback controls

1 reference

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7 January 2021

Comparison of kinetics of X-ray-induced cell killing in normal, ataxia telangiectasia and hereditary retinoblastoma fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Universal control mechanism regulating onset of M-phase

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Radiosensitivity in ataxia-telangiectasia: a new explanation

1 reference

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7 January 2021

Increased initial levels of chromosome damage and heterogeneous chromosome repair in ataxia telangiectasia heterozygote cells

1 reference

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7 January 2021

Defective excision repair of γ-ray-damaged DNA in human (ataxia telangiectasia) fibroblasts

1 reference

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7 January 2021

A checkpoint regulates the rate of progression through S phase in S. cerevisiae in response to DNA damage.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

An instance of clinical radiation morbidity and cellular radiosensitivity, not associated with ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

A 14/14 marker chromosome lymphocyte clone in ataxia telangiectasia

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Structural relationship between an iron-regulated RNA-binding protein (IRE-BP) and aconitase: functional implications

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Involvement of growth factor receptors in the mammalian UVC response

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

A single ataxia telangiectasia gene with a product similar to PI-3 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

The complete sequence of the coding region of the ATM gene reveals similarity to cell cycle regulators in different species

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Cell cycle dependence of mitotic delay in X-irradiated normal and ataxia-telangiectasia fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Interaction between ATM protein and c-Abl in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Abnormal response of ataxia-telangiectasia cells to agents that break the deoxyribose moiety of DNA via a targeted free radical mechanism.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Colony-forming ability of ataxia-telangiectasia skin fibroblasts is an indicator of their early senescence and increased demand for growth factors

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Primary structure of human T-cell receptor alpha-chain

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

DNA-binding protein activated by gamma radiation in human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Impairment of V(D)J recombination in double-strand break repair mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Ataxia telangiectasia: a human mutation with abnormal radiation sensitivity

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Differences in the DNA Supercoiling Response of Irradiated Cell Lines from Ataxia-telangiectasia Versus Unaffected Individuals

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Variant forms of ataxia telangiectasia

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Nomenclature of human genes involved in ionizing radiation sensitivity.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Genomic Organization of the ATM gene

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

A high-density microsatellite map of the ataxia-telangiectasia locus

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

The role of the stress-activated protein kinase (SAPK/JNK) signaling pathway in radiation-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

DNA strand breakage repair in ataxia telangiectasia fibroblast-like cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Reduced oxygen species, mutation, induction and cancer initiation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Cellular localisation of the ataxia-telangiectasia (ATM) gene product and discrimination between mutated and normal forms

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Characterization of RAD9 of Saccharomyces cerevisiae and evidence that its function acts posttranslationally in cell cycle arrest after DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Dual roles of ATM in the cellular response to radiation and in cell growth control.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Molecular aspects of cellular responses to radiotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Role for c-Abl tyrosine kinase in growth arrest response to DNA damage.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Mammalian mutants defective in the response to ionizing radiation-induced DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

TOR kinase domains are required for two distinct functions, only one of which is inhibited by rapamycin

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Isolation of full-length ATM cDNA and correction of the ataxia-telangiectasia cellular phenotype

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Ataxia-telangiectasia: a variant with altered in vitro phenotype of fibroblast cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

Recombinant ATM protein complements the cellular A-T phenotype

1 reference

https://api.crossref.org/works/10.1016%2FS0167-8140%2898%2900027-9

7 January 2021

10.1016/S0167-8140(98)00027-9

Identifiers

DOI

1 reference

5 February 2018

PubMed ID

9683357

1 reference

5 February 2018