(Q47770377)

5 February 2018

review article

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title

Localization and possible functions of presenilins in brain (English)

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5 February 2018

author name string

McGeer PL

series ordinal

1

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5 February 2018

Kawamata T

series ordinal

2

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5 February 2018

McGeer EG

series ordinal

3

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5 February 2018

publication date

1 January 1998

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5 February 2018

Reviews in the Neurosciences

published in

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5 February 2018

volume

9

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5 February 2018

issue

1

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5 February 2018

page(s)

1-15

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5 February 2018

Human presenilin-1, but not familial Alzheimer's disease (FAD) mutants, facilitate Caenorhabditis elegans Notch signalling independently of proteolytic processing

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1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

Regional and cellular localization of presenilin-2 RNA in rat and human brain

21 January 2018

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Immunohistochemical analysis of presenilin 2 expression in the mouse brain: distribution pattern and co-localization with presenilin 1 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

Molecular cloning, sequencing, and brain expression of the presenilin 1 gene in Microcebus murinus

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

The structure of the presenilin 1 (S182) gene and identification of six novel mutations in early onset AD families

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

Expression and analysis of presenilin 1 in a human neuronal system: localization in cell bodies and dendrites

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

Gene expression of Alzheimer-associated presenilin-2 in the frontal cortex of Alzheimer and aged control brain

21 January 2018

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https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

Alzheimer-associated presenilin-2 confers increased sensitivity to apoptosis in PC12 cells

21 January 2018

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https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

Phosphorylation, subcellular localization, and membrane orientation of the Alzheimer's disease-associated presenilins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

Amyloid, the presenilins and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

Developmental regulation of presenilin-1 processing in the brain suggests a role in neuronal differentiation

21 January 2018

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https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

Processing of presenilin 1 in brains of patients with Alzheimer's disease and controls.

21 January 2018

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https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

Increased A beta 42(43)-plaque deposition in early-onset familial Alzheimer's disease brains with the deletion of exon 9 and the missense point mutation (H163R) in the PS-1 gene.

21 January 2018

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https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

Possible role of neuronal apoptosis in Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

Quantification of presenilin-1 mRNA in Alzheimer's disease brains.

21 January 2018

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https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

Alternative cleavage of Alzheimer-associated presenilins during apoptosis by a caspase-3 family protease

21 January 2018

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https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

Immunoreactivity of presenilin-1 in human, rat and mouse brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

Alzheimer-associated presenilins 1 and 2: neuronal expression in brain and localization to intracellular membranes in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

Two novel (M233T and R278T) presenilin-1 mutations in early-onset Alzheimer's disease pedigrees and preliminary evidence for association of presenilin-1 mutations with a novel phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

Hyperaccumulation of FAD-linked presenilin 1 variants in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

Evidence for a six-transmembrane domain structure of presenilin 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

The E280A presenilin 1 Alzheimer mutation produces increased A beta 42 deposition and severe cerebellar pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

Presenilin-1 protein expression in familial and sporadic Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

Alzheimer presenilins in the nuclear membrane, interphase kinetochores, and centrosomes suggest a role in chromosome segregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

Amyloid beta protein (Abeta) deposition in chromosome 14-linked Alzheimer's disease: predominance of Abeta42(43).

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

Cell and molecular neurobiology of presenilins: a role for the endoplasmic reticulum in the pathogenesis of Alzheimer's disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

Immunohistochemical analysis of presenilin-1 expression in the mouse brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

In situ hybridization analysis of presenilin 1 mRNA in Alzheimer disease and in lesioned rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

Analysis of the 5' sequence, genomic structure, and alternative splicing of the presenilin-1 gene (PSEN1) associated with early onset Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

Skeletal and CNS defects in Presenilin-1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

Alzheimer's disease associated with mutations in presenilin 2 is rare and variably penetrant.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

Regional and cellular presenilin 1 gene expression in human and rat tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

Expression of presenilin-1 and -2 mRNAs in rat and Alzheimer's disease brains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

Localization of Alzheimer-associated presenilin 1 in transfected COS-7 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

The presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid beta protein ending at the 42nd (or 43rd) residue

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

Widespread immunoreactivity of presenilin in neurons of normal and Alzheimer's disease brains: double-labeling immunohistochemical study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

A novel pathogenic mutation (Leu262Phe) found in the presenilin 1 gene in early-onset Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

Presenilin Proteins Undergo Heterogeneous Endoproteolysis between Thr291and Ala299and Occur as Stable N- and C-Terminal Fragments in Normal and Alzheimer Brain Tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.1998.9.1.1

10.1515/REVNEURO.1998.9.1.1

21 January 2018

Identifiers

DOI

1 reference

5 February 2018

1 reference

5 February 2018