(Q47771236)

21 February 2018

title

Delayed neutrophil apoptosis enhances NET formation in cystic fibrosis (English)

1 reference

21 February 2018

0 references

Gordon Cooke

14

0 references

Robert D Gray

Robert D Gray

1

0 references

David Stoltz

David A Stoltz

17

0 references

Paul B McCray

Paul B McCray

19

0 references

Rodger Duffin

Rodger Duffin

6

0 references

Seamas C. Donnelly

Seamas C Donnelly

15

0 references

Christopher D Lucas

Christopher D Lucas

11

0 references

Lily Paemka

9

Lily Paemka

1 reference

21 February 2018

Moira K B Whyte

20

Moira K B Whyte

1 reference

21 February 2018

author name string

Gareth Hardisty

2

1 reference

21 February 2018

Kate H Regan

3

1 reference

21 February 2018

Maeve Smith

4

1 reference

21 February 2018

Calum T Robb

5

1 reference

21 February 2018

Annie Mackellar

7

1 reference

21 February 2018

Jennifer M Felton

8

1 reference

21 February 2018

Brian N McCullagh

10

1 reference

21 February 2018

David A Dorward

12

1 reference

21 February 2018

Edward F McKone

13

1 reference

21 February 2018

Pradeep K Singh

16

1 reference

21 February 2018

Christopher Haslett

18

1 reference

21 February 2018

Adriano G Rossi

21

1 reference

21 February 2018

Donald J Davidson

22

1 reference

21 February 2018

language of work or name

English

0 references

publication date

15 September 2017

1 reference

21 February 2018

published in

Thorax

1 reference

21 February 2018

volume

73

1 reference

21 February 2018

issue

2

1 reference

21 February 2018

page(s)

134-144

1 reference

21 February 2018

Monocyte derived macrophages from CF pigs exhibit increased inflammatory responses at birth.

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22 May 2018

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22 May 2018

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Acute administration of ivacaftor to people with cystic fibrosis and a G551D-CFTR mutation reveals smooth muscle abnormalities

22 May 2018

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22 May 2018

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Inflammation. Neutrophil extracellular traps license macrophages for cytokine production in atherosclerosis

22 May 2018

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Lumacaftor-Ivacaftor in Patients with Cystic Fibrosis Homozygous for Phe508del CFTR.

22 May 2018

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Alterations in blood leukocytes of G551D-bearing cystic fibrosis patients undergoing treatment with ivacaftor

22 May 2018

1 reference

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Pharmacological modulation of the AKT/microRNA-199a-5p/CAV1 pathway ameliorates cystic fibrosis lung hyper-inflammation

22 May 2018

1 reference

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Neutrophil-mediated phagocytic host defense defect in myeloid Cftr-inactivated mice

22 May 2018

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A neutrophil intrinsic impairment affecting Rab27a and degranulation in cystic fibrosis is corrected by CFTR potentiator therapy

22 May 2018

1 reference

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Cystic fibrosis sputum DNA has NETosis characteristics and neutrophil extracellular trap release is regulated by macrophage migration-inhibitory factor

22 May 2018

1 reference

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Downregulation of Mcl-1 has anti-inflammatory pro-resolution effects and enhances bacterial clearance from the lung

22 May 2018

1 reference

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Macrophage clearance of neutrophil extracellular traps is a silent process

22 May 2018

1 reference

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Pivotal role for the mTOR pathway in the formation of neutrophil extracellular traps via regulation of autophagy

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5771859

NETs are a source of citrullinated autoantigens and stimulate inflammatory responses in rheumatoid arthritis

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5771859

Activation of conventional protein kinase C (PKC) is critical in the generation of human neutrophil extracellular traps

22 May 2018

1 reference

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Flavones induce neutrophil apoptosis by down-regulation of Mcl-1 via a proteasomal-dependent pathway

22 May 2018

1 reference

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Cyclin-dependent kinases 7 and 9 specifically regulate neutrophil transcription and their inhibition drives apoptosis to promote resolution of inflammation.

22 May 2018

1 reference

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Cyclin-dependent kinase 9 activity regulates neutrophil spontaneous apoptosis

22 May 2018

1 reference

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Neutrophil extracellular trap formation is associated with IL-1β and autophagy-related signaling in gout

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5771859

Neutrophil elastase enhances sputum solubilization in cystic fibrosis patients receiving DNase therapy

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5771859

A CFTR potentiator in patients with cystic fibrosis and the G551D mutation

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5771859

Ultrastructural characterization of cystic fibrosis sputum using atomic force and scanning electron microscopy

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5771859

Neutrophil extracellular trap (NET)-mediated killing of Pseudomonas aeruginosa: evidence of acquired resistance within the CF airway, independent of CFTR.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5771859

Netting neutrophils induce endothelial damage, infiltrate tissues, and expose immunostimulatory molecules in systemic lupus erythematosus.

22 May 2018

1 reference

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Netting neutrophils are major inducers of type I IFN production in pediatric systemic lupus erythematosus

22 May 2018

1 reference

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Dying for a cause: NETosis, mechanisms behind an antimicrobial cell death modality

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5771859

Neutrophil extracellular trap cell death requires both autophagy and superoxide generation

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5771859

Myeloperoxidase is required for neutrophil extracellular trap formation: implications for innate immunity

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5771859

Coronin-1 is associated with neutrophil survival and is cleaved during apoptosis: potential implication in neutrophils from cystic fibrosis patients

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5771859

Activation of critical, host-induced, metabolic and stress pathways marks neutrophil entry into cystic fibrosis lungs

22 May 2018

1 reference

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Innate immune functions of the airway epithelium

22 May 2018

1 reference

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The role of chloride anion and CFTR in killing of Pseudomonas aeruginosa by normal and CF neutrophils

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5771859

Profound functional and signaling changes in viable inflammatory neutrophils homing to cystic fibrosis airways

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5771859

Macrophage activation and polarization

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5771859

Beneficial suicide: why neutrophils die to make NETs

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5771859

IL-4 induces expression of TARC/CCL17 via two STAT6 binding sites

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5771859

Neutrophil extracellular traps kill bacteria

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5771859

Cytokine-mediated Bax deficiency and consequent delayed neutrophil apoptosis: a general mechanism to accumulate effector cells in inflammation

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5771859

The cyclin-dependent kinase inhibitor AT7519 accelerates neutrophil apoptosis in sepsis-related acute respiratory distress syndrome.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5771859

Ivacaftor-Induced Proteomic Changes Suggest Monocyte Defects May Contribute to the Pathogenesis of Cystic Fibrosis.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5771859

Dogs cast NETs too: Canine neutrophil extracellular traps in health and immune-mediated hemolytic anemia.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5771859

Expression and regulation of glycogen synthase kinase 3 in human neutrophils.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5771859

GSK3β inhibition is involved in the neuroprotective effects of cyclin-dependent kinase inhibitors in neurons.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5771859

Role for myeloid nuclear differentiation antigen in the regulation of neutrophil apoptosis during sepsis.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5771859

In cystic fibrosis homozygotes and heterozygotes, neutrophil apoptosis is delayed and modulated by diamide or roscovitine: evidence for an innate neutrophil disturbance

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5771859

CFTR regulates phagosome acidification in macrophages and alters bactericidal activity

14 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28916704

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Epidemiologic study of cystic fibrosis: design and implementation of a prospective, multicenter, observational study of patients with cystic fibrosis in the U.S. and Canada

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28916704

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Prolonged survival of neutrophils from patients with F508 CFTR mutations

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28916704

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1136/THORAXJNL-2017-210134

1 reference

21 February 2018

PMCID

5771859

1 reference

21 February 2018

PubMed ID

28916704

1 reference

21 February 2018