(Q47793480)

5 February 2018

title

The unmet need in the elderly: designing new influenza vaccines for older adults (English)

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5 February 2018

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1

Janet E McElhaney

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5 February 2018

language of work or name

English

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publication date

1 July 2005

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5 February 2018

published in

Vaccine

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5 February 2018

volume

23 Suppl 1

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5 February 2018

page(s)

S10-25

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5 February 2018

Influenza and the winter increase in mortality in the United States, 1959-1999.

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Split-virus influenza vaccines: do they provide adequate immunity in the elderly?

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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A novel serine esterase expressed by cytotoxic T lymphocytes

7 January 2021

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The isolation and characterization of a family of serine protease genes expressed in activated cytotoxic T lymphocytes

7 January 2021

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Granzymes, a family of serine proteases released from granules of cytolytic T lymphocytes upon T cell receptor stimulation

7 January 2021

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Fas involvement in Ca(2+)-independent T cell-mediated cytotoxicity

7 January 2021

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7 January 2021

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7 January 2021

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Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

7 January 2021

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The cell-mediated cytotoxic response to influenza vaccination using an assay for granzyme B activity

7 January 2021

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7 January 2021

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7 January 2021

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Single-cell perforin and granzyme expression reveals the anatomical localization of effector CD8+ T cells in influenza virus-infected mice.

7 January 2021

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Heterotypic immune mice lose protection against influenza virus infection with senescence

7 January 2021

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Influenza A virus-specific cytotoxic T lymphocyte activity declines with advancing age.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VACCINE.2005.04.019

Diminished influenza A virus-specific MHC class I-restricted cytotoxic T lymphocyte activity among elderly persons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2005.04.019

Age-associated change in the frequency of memory CD4+ T cells impairs long term CD4+ T cell responses to influenza vaccine

7 January 2021

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The immunology of exceptional individuals: the lesson of centenarians.

7 January 2021

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Immune Parameters in a Longitudinal Study of a Very Old Population of Swedish People: A Comparison Between Survivors and Nonsurvivors

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VACCINE.2005.04.019

Loss of CD28 expression on T lymphocytes: a marker of replicative senescence

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2005.04.019

In vitro senescence of immune cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2005.04.019

Decline in CD28+ T cells in centenarians and in long-term T cell cultures: a possible cause for both in vivo and in vitro immunosenescence

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2005.04.019

Genetic alterations in the ageing immune system: impact on infection and cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2005.04.019

Value of immunological markers in predicting responsiveness to influenza vaccination in elderly individuals

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2005.04.019

Lack of antibody production following immunization in old age: association with CD8(+)CD28(-) T cell clonal expansions and an imbalance in the production of Th1 and Th2 cytokines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2005.04.019

Hypothesis: loss of telomerase inducibility and subsequent replicative senescence in cultured human T cells is a result of altered costimulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2005.04.019

Costimulatory mechanisms in the elderly

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2005.04.019

CD28 expression in T cell aging and human longevity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2005.04.019

Differentiation of human CD8 T cells: implications for in vivo persistence of CD8+ CD28- cytotoxic effector clones.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2005.04.019

Insights on immunological aging derived from the T lymphocyte cellular senescence model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2005.04.019

Influenza A virus specific T cell immunity in humans during aging

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2005.04.019

Loss of CD28 expression on CD8(+) T cells is induced by IL-2 receptor gamma chain signalling cytokines and type I IFN, and increases susceptibility to activation-induced apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2005.04.019

Direct measurement of T cell subset kinetics in vivo in elderly men and women

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2005.04.019

Novel features of the respiratory tract T-cell response to influenza virus infection: lung T cells increase expression of gamma interferon mRNA in vivo and maintain high levels of mRNA expression for interleukin-5 (IL-5) and IL-10.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2005.04.019

inferred from DOI database lookup

7 January 2021

based on heuristic

Evolutionary analysis of the influenza A virus M gene with comparison of the M1 and M2 proteins

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2005.04.019

inferred from DOI database lookup

7 January 2021

based on heuristic

Enhancement of anti-influenza A virus cytotoxicity following influenza A virus vaccination in older, chronically ill adults

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2005.04.019

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.VACCINE.2005.04.019

1 reference

5 February 2018

1 reference

5 February 2018