(Q47797190)

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Implications of enzyme deficiencies on mitochondrial energy metabolism and reactive oxygen species formation of neurons involved in rotenone-induced Parkinson's disease: a model-based analysis.

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scholarly article

1 reference

Europe PubMed Central

5 February 2018

http://europepmc.org/abstract/MED/23937586

Implications of enzyme deficiencies on mitochondrial energy metabolism and reactive oxygen species formation of neurons involved in rotenone-induced Parkinson's disease: a model-based analysis. (English)

1 reference

Europe PubMed Central

5 February 2018

http://europepmc.org/abstract/MED/23937586

reactive oxygen species

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based on heuristic

inferred from title

Parkinson's disease

1 reference

based on heuristic

inferred from title

Nikolaus Berndt

1

object named as

Nikolaus Berndt

1 reference

Europe PubMed Central

5 February 2018

http://europepmc.org/abstract/MED/23937586

3

object named as

Sascha Bulik

1 reference

Europe PubMed Central

5 February 2018

http://europepmc.org/abstract/MED/23937586

author name string

Herrmann-Georg Holzhütter

2

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Europe PubMed Central

5 February 2018

http://europepmc.org/abstract/MED/23937586

language of work or name

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publication date

12 September 2013

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Europe PubMed Central

5 February 2018

http://europepmc.org/abstract/MED/23937586

1 reference

Europe PubMed Central

5 February 2018

http://europepmc.org/abstract/MED/23937586

280

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Europe PubMed Central

5 February 2018

http://europepmc.org/abstract/MED/23937586

20

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Europe PubMed Central

5 February 2018

http://europepmc.org/abstract/MED/23937586

5080-5093

1 reference

Europe PubMed Central

5 February 2018

http://europepmc.org/abstract/MED/23937586

α-Synuclein: membrane interactions and toxicity in Parkinson's disease

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A review of Parkinson's disease

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Mitochondria in the aetiology and pathogenesis of Parkinson's disease

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Complex I deficiency in Parkinson's disease frontal cortex

1 reference

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Parkinson's disease brain mitochondrial complex I has oxidatively damaged subunits and is functionally impaired and misassembled.

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Deficits in a tricarboxylic acid cycle enzyme in brains from patients with Parkinson's disease

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An immunohistochemical study on alpha-ketoglutarate dehydrogenase complex in Parkinson's disease.

1 reference

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How mitochondria produce reactive oxygen species

1 reference

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Quantitative relationship between inhibition of respiratory complexes and formation of reactive oxygen species in isolated nerve terminals.

1 reference

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Origin and functional consequences of the complex I defect in Parkinson's disease

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Animal models of Parkinson's disease.

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Chronic systemic pesticide exposure reproduces features of Parkinson's disease

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Ca(2+)-dependent changes in the mitochondrial energetics in single dissociated mouse sensory neurons

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Energy thresholds in brain mitochondria. Potential involvement in neurodegeneration.

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Kinetic Modeling of the Mitochondrial Energy Metabolism of Neuronal Cells: The Impact of Reduced α-Ketoglutarate Dehydrogenase Activities on ATP Production and Generation of Reactive Oxygen Species

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The relationship between free and total calcium concentrations in the matrix of liver and brain mitochondria.

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Energy converting NADH:quinone oxidoreductase (complex I).

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Three classes of inhibitors share a common binding domain in mitochondrial complex I (NADH:ubiquinone oxidoreductase).

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Multistationary and oscillatory modes of free radicals generation by the mitochondrial respiratory chain revealed by a bifurcation analysis

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Reactive oxygen species production by forward and reverse electron fluxes in the mitochondrial respiratory chain

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Bistability of mitochondrial respiration underlies paradoxical reactive oxygen species generation induced by anoxia

1 reference

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Oxygen consumption rates during three different neuronal activity states in the hippocampal CA3 network

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Non-ohmic proton conductance of mitochondria and liposomes.

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Proton/electron stoichiometry of mitochondrial complex I estimated from the equilibrium thermodynamic force ratio

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Mitochondria deficient in complex I activity are depolarized by hydrogen peroxide in nerve terminals: relevance to Parkinson's disease

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Mitochondrial consumption of cytosolic ATP: not so fast.

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Forward operation of adenine nucleotide translocase during F0F1-ATPase reversal: critical role of matrix substrate-level phosphorylation

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21 January 2018

The mechanism of superoxide production by NADH:ubiquinone oxidoreductase (complex I) from bovine heart mitochondria

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21 January 2018

Anatomic and disease specificity of NADH CoQ1 reductase (complex I) deficiency in Parkinson's disease

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The synaptic pathology of alpha-synuclein aggregation in dementia with Lewy bodies, Parkinson's disease and Parkinson's disease dementia

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Production of reactive oxygen species in brain mitochondria: contribution by electron transport chain and non-electron transport chain sources

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21 January 2018

Pathogenesis of nigral cell death in Parkinson's disease

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Inactivation and reactivation of the mitochondrial α-ketoglutarate dehydrogenase complex

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21 January 2018

A trial of thiamine in Alzheimer's disease

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The alpha-ketoglutarate dehydrogenase complex in neurodegeneration

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Ubiquitin-proteasome system and Parkinson's diseases

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Parkinson's disease: mechanisms and models

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21 January 2018

Mitochondrial import and accumulation of alpha-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain

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21 January 2018

Peroxidase mechanism of lipid-dependent cross-linking of synuclein with cytochrome C: protection against apoptosis versus delayed oxidative stress in Parkinson disease

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21 January 2018

Influence of complete ischemia on glycolytic metabolites, citric acid cycle intermediates, and associated amino acids in the rat cerebral cortex.

1 reference

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Regulation by bicarbonate ion of intramitochondrial citrate concentration in kidney mitochondria

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Levels of cerebral cortical glycolytic and citric acid cycle metabolites during hypoglycemic stupor and its reversal

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21 January 2018

Identifiers

10.1111/FEBS.12480

1 reference

Europe PubMed Central

5 February 2018

http://europepmc.org/abstract/MED/23937586

1 reference

Europe PubMed Central

5 February 2018

http://europepmc.org/abstract/MED/23937586

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