(Q47810902)

5 February 2018

title

A caspase active site probe reveals high fractional inhibition needed to block DNA fragmentation (English)

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5 February 2018

1

Nathalie Méthot

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5 February 2018

Yongxin Han

5

object named as

Yongxin Han

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5 February 2018

John Colucci

4

object named as

John Colucci

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5 February 2018

author name string

John P Vaillancourt

2

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5 February 2018

JingQi Huang

3

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5 February 2018

Stéphane Ménard

6

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5 February 2018

Robert Zamboni

7

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5 February 2018

Sylvie Toulmond

8

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5 February 2018

Donald W Nicholson

9

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5 February 2018

Sophie Roy

10

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5 February 2018

language of work or name

English

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publication date

5 April 2004

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5 February 2018

Journal of Biological Chemistry

number of pages

10

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based on heuristic

inferred from page(s)

published in

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5 February 2018

volume

279

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5 February 2018

issue

27

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5 February 2018

page(s)

27905-27914

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5 February 2018

The biochemistry of apoptosis

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Caspase structure, proteolytic substrates, and function during apoptotic cell death

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Mechanisms of caspase activation and inhibition during apoptosis

21 January 2018

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Executioner caspase-3, -6, and -7 perform distinct, non-redundant roles during the demolition phase of apoptosis.

21 January 2018

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Caspases: enemies within

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Proteolysis of fodrin (non-erythroid spectrin) during apoptosis.

21 January 2018

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The 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosis

21 January 2018

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A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

21 January 2018

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Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis

21 January 2018

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Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins

21 January 2018

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From bench to clinic with apoptosis-based therapeutic agents

21 January 2018

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Apoptosis-based therapies

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Attenuation of delayed neuronal death after mild focal ischemia in mice by inhibition of the caspase family.

21 January 2018

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Selective, reversible caspase-3 inhibitor is neuroprotective and reveals distinct pathways of cell death after neonatal hypoxic-ischemic brain injury

21 January 2018

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A novel nonpeptidic caspase-3/7 inhibitor, (S)-(+)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatin reduces myocardial ischemic injury

21 January 2018

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Caspase inhibitors improve survival in sepsis: a critical role of the lymphocyte

21 January 2018

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Caspase inhibition reduces apoptosis and increases survival of nigral transplants

21 January 2018

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Caspase inhibition by Z-VAD increases the survival of grafted bone marrow cells and improves functional outcome after MCAo in rats

21 January 2018

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Non-invasive radiotracer imaging as a tool for drug development

21 January 2018

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Measuring receptor occupancy with PET.

21 January 2018

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Maintenance of caspase-3 proenzyme dormancy by an intrinsic "safety catch" regulatory tripeptide

21 January 2018

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Prevention of lymphocyte cell death in sepsis improves survival in mice

21 January 2018

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Increased susceptibility to apoptosis in circulating lymphocytes of critically ill patients

21 January 2018

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Activation of apoptosis pathways in peripheral blood lymphocytes by in vivo chemotherapy

21 January 2018

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Simultaneous Degradation of αII- and βII-Spectrin by Caspase 3 (CPP32) in Apoptotic Cells

21 January 2018

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Cleavage of FLICE (caspase-8) by granzyme B during cytotoxic T lymphocyte-induced apoptosis

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M400247200

1 reference

5 February 2018

1 reference

5 February 2018