(Q47814140)

English

Site-specific footprinting reveals differences in the translocation status of HIV-1 reverse transcriptase. Implications for polymerase translocation and drug resistance

scientific article published on 20 June 2003

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

5 February 2018

http://europepmc.org/abstract/MED/12819205

Site-specific footprinting reveals differences in the translocation status of HIV-1 reverse transcriptase. Implications for polymerase translocation and drug resistance (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 February 2018

http://europepmc.org/abstract/MED/12819205

author name string

Bruno Marchand

1

1 reference

Europe PubMed Central

PubMed publication ID

5 February 2018

http://europepmc.org/abstract/MED/12819205

Matthias Götte

2

1 reference

Europe PubMed Central

PubMed publication ID

5 February 2018

http://europepmc.org/abstract/MED/12819205

language of work or name

0 references

publication date

20 June 2003

1 reference

Europe PubMed Central

PubMed publication ID

5 February 2018

http://europepmc.org/abstract/MED/12819205

number of pages

11

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based on heuristic

inferred from page(s)

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

5 February 2018

http://europepmc.org/abstract/MED/12819205

278

1 reference

Europe PubMed Central

PubMed publication ID

5 February 2018

http://europepmc.org/abstract/MED/12819205

37

1 reference

Europe PubMed Central

PubMed publication ID

5 February 2018

http://europepmc.org/abstract/MED/12819205

35362-35372

1 reference

Europe PubMed Central

PubMed publication ID

5 February 2018

http://europepmc.org/abstract/MED/12819205

Phenotypic mechanism of HIV-1 resistance to 3'-azido-3'-deoxythymidine (AZT): increased polymerization processivity and enhanced sensitivity to pyrophosphate of the mutant viral reverse transcriptase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304262200

21 January 2018

Unblocking of chain-terminated primer by HIV-1 reverse transcriptase through a nucleotide-dependent mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304262200

21 January 2018

A mechanism of AZT resistance: an increase in nucleotide-dependent primer unblocking by mutant HIV-1 reverse transcriptase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304262200

21 January 2018

Role of a dipeptide insertion between codons 69 and 70 of HIV-1 reverse transcriptase in the mechanism of AZT resistance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304262200

21 January 2018

Effects of dipeptide insertions between codons 69 and 70 of human immunodeficiency virus type 1 reverse transcriptase on primer unblocking, deoxynucleoside triphosphate inhibition, and DNA chain elongation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304262200

21 January 2018

Nucleoside analog resistance caused by insertions in the fingers of human immunodeficiency virus type 1 reverse transcriptase involves ATP-mediated excision.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304262200

21 January 2018

Selective excision of AZTMP by drug-resistant human immunodeficiency virus reverse transcriptase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304262200

21 January 2018

Correlation between viral resistance to zidovudine and resistance at the reverse transcriptase level for a panel of human immunodeficiency virus type 1 mutants

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304262200

21 January 2018

Primer unblocking and rescue of DNA synthesis by azidothymidine (AZT)-resistant HIV-1 reverse transcriptase: comparison between initiation and elongation of reverse transcription and between (-) and (+) strand DNA synthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304262200

21 January 2018

ATP-dependent removal of nucleoside reverse transcriptase inhibitors by human immunodeficiency virus type 1 reverse transcriptase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304262200

21 January 2018

The M184V mutation in the reverse transcriptase of human immunodeficiency virus type 1 impairs rescue of chain-terminated DNA synthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304262200

21 January 2018

Single-step kinetics of HIV-1 reverse transcriptase mutants responsible for virus resistance to nucleoside inhibitors zidovudine and 3-TC.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304262200

21 January 2018

Enhanced binding of azidothymidine-resistant human immunodeficiency virus 1 reverse transcriptase to the 3'-azido-3'-deoxythymidine 5'-monophosphate-terminated primer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304262200

21 January 2018

The emergence of different resistance mechanisms toward nucleoside inhibitors is explained by the properties of the wild type HIV-1 reverse transcriptase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304262200

21 January 2018

Multidrug-resistant HIV-1 reverse transcriptase: involvement of ribonucleotide-dependent phosphorolysis in cross-resistance to nucleoside analogue inhibitors.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304262200

21 January 2018

Structures of HIV-1 reverse transcriptase with pre- and post-translocation AZTMP-terminated DNA.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304262200

21 January 2018

Trapping HIV-1 reverse transcriptase before and after translocation on DNA.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304262200

21 January 2018

Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304262200

21 January 2018

Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody Fab fragment at 2.8 A resolution

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304262200

21 January 2018

Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304262200

21 January 2018

Rapid purification of homodimer and heterodimer HIV-1 reverse transcriptase by metal chelate affinity chromatography.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304262200

21 January 2018

Localization of the active site of HIV-1 reverse transcriptase-associated RNase H domain on a DNA template using site-specific generated hydroxyl radicals

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304262200

21 January 2018

Hydroxyl radical footprint analysis of human immunodeficiency virus reverse transcriptase-template.primer complexes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304262200

21 January 2018

Pathways of peroxynitrite oxidation of thiol groups

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304262200

21 January 2018

Structural transitions mediating transcription initiation by T7 RNA polymerase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304262200

21 January 2018

Structural analysis of ternary complexes of Escherichia coli RNA polymerase. Deoxyribonuclease I footprinting of defined complexes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304262200

21 January 2018

Kinetic mechanism of DNA polymerase I(Klenow fragment): identification of a second conformational change and evaluation of the internal equilibrium constant

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304262200

21 January 2018

An open and closed case for all polymerases.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304262200

21 January 2018

Structure of the replicating complex of a pol alpha family DNA polymerase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304262200

21 January 2018

Touching the heart of HIV-1 drug resistance: the fingers close down on the dNTP at the polymerase active site

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304262200

21 January 2018

A model for the mechanism of polymerase translocation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304262200

21 January 2018

NTP concentration effects on initial transcription by T7 RNAP indicate that translocation occurs through passive sliding and reveal that divergent promoters have distinct NTP concentration requirements for productive initiation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304262200

21 January 2018

'Footprinting' proteins on DNA with peroxonitrous acid

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304262200

21 January 2018

Structures of complexes formed by HIV-1 reverse transcriptase at a termination site of DNA synthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304262200

21 January 2018

Drug binding to a DNA BZ molecule: analysis by chemical footprinting

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304262200

21 January 2018

Identifiers

10.1074/JBC.M304262200

1 reference

Europe PubMed Central

PubMed publication ID

5 February 2018

http://europepmc.org/abstract/MED/12819205

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 February 2018

http://europepmc.org/abstract/MED/12819205

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