(Q47816202)

http://europepmc.org/abstract/MED/25208486

5 February 2018

title

Integrin-linked kinase mediates force transduction in cardiomyocytes by modulating SERCA2a/PLN function (English)

1 reference

http://europepmc.org/abstract/MED/25208486

5 February 2018

author

Luc Mertens

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25208486%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Paul Delgado-Olguín

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25208486%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

author name string

Alexandra Traister

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25208486%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Mark Li

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25208486%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Shabana Aafaqi

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25208486%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Mingliang Lu

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25208486%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Sara Arab

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25208486%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Milica Radisic

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25208486%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Gil Gross

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25208486%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Fiorella Guido

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25208486%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

John Sherret

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25208486%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Subodh Verma

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25208486%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Cameron Slorach

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25208486%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Wei Hui

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25208486%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Anna Roy

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25208486%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Gregory Hannigan

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25208486%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Jason T Maynes

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25208486%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

John G Coles

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25208486%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

language of work or name

English

0 references

publication date

11 September 2014

1 reference

http://europepmc.org/abstract/MED/25208486

5 February 2018

published in

Nature Communications

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25208486%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

volume

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25208486%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

page(s)

4533

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25208486%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/ncomms5533

1 June 2020

exact match

0 references

cites work

Familial dilated cardiomyopathy. Clinical and genetic characteristics.

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Genetic mutations and mechanisms in dilated cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Calcium cycling proteins and heart failure: mechanisms and therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Phosphorylation and mutation of phospholamban alter physical interactions with the sarcoplasmic reticulum calcium pump

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Modulation of cardiac contractility by the phospholamban/SERCA2a regulatome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID): a phase 2 trial of intracoronary gene therapy of sarcoplasmic reticulum Ca2+-ATPase in patients with advanced heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Sarcoplasmic reticulum and calcium cycling targeting by gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Cardiac Z-disc signaling network

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

PINCH proteins regulate cardiac contractility by modulating integrin-linked kinase-protein kinase B signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Integrin-linked kinase, a novel component of the cardiac mechanical stretch sensor, controls contractility in the zebrafish heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Integrin-linked kinase at the heart of cardiac contractility, repair, and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Laminin-alpha4 and integrin-linked kinase mutations cause human cardiomyopathy via simultaneous defects in cardiomyocytes and endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Targeted ablation of ILK from the murine heart results in dilated cardiomyopathy and spontaneous heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

The structure and function of cardiac t-tubules in health and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Molecular basis of physiological heart growth: fundamental concepts and new players

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Integrin alphavbeta3 upregulates integrin-linked kinase expression in human ovarian cancer cells via enhancement of ILK gene transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

The role of CaMKII regulation of phospholamban activity in heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Stem cells and their derivatives: a renaissance in cardiovascular translational research

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

High purity human-induced pluripotent stem cell-derived cardiomyocytes: electrophysiological properties of action potentials and ionic currents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

GSK-3beta, a therapeutic target for cardiomyocyte protection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Integrin-linked kinase: not so 'pseudo' after all.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Integrin-linked kinase is a functional Mn2+-dependent protein kinase that regulates glycogen synthase kinase-3β (GSK-3beta) phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

The oncogenic and growth-suppressive functions of the integrin-linked kinase are distinguished by JNK1 expression in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) in the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Biochemical, proteomic, structural, and thermodynamic characterizations of integrin-linked kinase (ILK): cross-validation of the pseudokinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Regulation of protein kinase B/Akt-serine 473 phosphorylation by integrin-linked kinase: critical roles for kinase activity and amino acids arginine 211 and serine 343

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Targeting PI3K signalling in cancer: opportunities, challenges and limitations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Integrin-linked kinase is an adaptor with essential functions during mouse development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Doxorubicin-induced cardiac dysfunction is attenuated by ciclosporin treatment in mice through improvements in mitochondrial bioenergetics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Doxorubicin cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Cancer therapy-induced cardiac toxicity in early breast cancer: addressing the unresolved issues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Sarcoplasmic reticulum Ca2+ pumping kinetics regulates timing of local Ca2+ releases and spontaneous beating rate of rabbit sinoatrial node pacemaker cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Differential control of calcium homeostasis and vascular reactivity by Ca2+/calmodulin-dependent kinase II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Biowire: a platform for maturation of human pluripotent stem cell-derived cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Calcium flux balance in the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Doxorubicin cardiac dysfunction: effects on calcium regulatory proteins, sarcoplasmic reticulum, and triiodothyronine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Impedance-based detection of beating rhythm and proarrhythmic effects of compounds on stem cell-derived cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Functional cardiotoxicity profiling and screening using the xCELLigence RTCA Cardio System

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Tissue Doppler imaging predicts left ventricular dysfunction and mortality in a murine model of cardiac injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Early detection and prediction of cardiotoxicity in chemotherapy-treated patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Assessment of echocardiography and biomarkers for the extended prediction of cardiotoxicity in patients treated with anthracyclines, taxanes, and trastuzumab

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

In vitro model for assessing arrhythmogenic properties of drugs based on high-resolution impedance measurements.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

SERCA2a gene transfer decreases sarcoplasmic reticulum calcium leak and reduces ventricular arrhythmias in a model of chronic heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Sarcoplasmic reticulum Ca(2+) ATPase as a therapeutic target for heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Increased nitration of sarcoplasmic reticulum Ca2+-ATPase in human heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Calmodulin-dependent protein kinase II: linking heart failure and arrhythmias

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

CaMKII inhibition in heart failure, beneficial, harmful, or both

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Sequential alterations in Akt, GSK3β, and calcineurin signalling in the mouse left ventricle after thoracic aortic constriction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Differences in MEF2 and NFAT transcriptional pathways according to human heart failure aetiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

LNK (SH2B3) is a key regulator of integrin signaling in endothelial cells and targets α-parvin to control cell adhesion and migration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Mutations in the paxillin-binding site of integrin-linked kinase (ILK) destabilize the pseudokinase domain and cause embryonic lethality in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

The impairment of ILK related angiogenesis involved in cardiac maladaptation after infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Mutation in integrin-linked kinase (ILK(R211A)) and heat-shock protein 70 comprise a broadly cardioprotective complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Stabilization of integrin-linked kinase by binding to Hsp90.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Subtle alterations in breathing and heart rate control in the 5-HT1A receptor knockout mouse in early postnatal development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Use of cardiac markers for monitoring of doxorubixin-induced cardiotoxicity in children with cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

Increased expression of cardiac phosphatases in patients with end-stage heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

7 January 2021

Integrin-linked kinase expression is elevated in human cardiac hypertrophy and induces hypertrophy in transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

7 January 2021

Patient-specific induced pluripotent stem cells as a model for familial dilated cardiomyopathy.

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

7 January 2021

Unchanged Protein Levels of SERCA II and Phospholamban but Reduced Ca 2+ Uptake and Ca 2+ -ATPase Activity of Cardiac Sarcoplasmic Reticulum From Dilated Cardiomyopathy Patients Compared With Patients With Nonfailing Hearts

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

7 January 2021

Ca(2+)-transporting ATPase, phospholamban, and calsequestrin levels in nonfailing and failing human myocardium

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

7 January 2021

Remote preconditioning provides potent cardioprotection via PI3K/Akt activation and is associated with nuclear accumulation of β-catenin

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

7 January 2021

Signaling pathways in reactive oxygen species-induced cardiomyocyte apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

7 January 2021

Integrin-Linked Kinase Regulates Vasomotor Function by Preventing Endothelial Nitric Oxide Synthase Uncoupling

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

7 January 2021

Gene therapy for heart failure

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5533

7 January 2021

Identifiers

DOI

10.1038/NCOMMS5533

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25208486%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

1 June 2020

ADS bibcode

2014NatCo...5.4533T

0 references

0 references

1 reference