(Q47826063)

5 February 2018

title

Rethinking HSF1 in Stress, Development, and Organismal Health. (English)

1 reference

5 February 2018

author name string

Jian Li

series ordinal

1

1 reference

5 February 2018

Johnathan Labbadia

series ordinal

2

1 reference

5 February 2018

Richard I Morimoto

series ordinal

3

1 reference

5 February 2018

publication date

7 September 2017

1 reference

5 February 2018

published in

Trends in Cell Biology

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5 February 2018

volume

27

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5 February 2018

issue

12

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5 February 2018

page(s)

895-905

1 reference

5 February 2018

Abnormal degradation of the neuronal stress-protective transcription factor HSF1 in Huntington's disease

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E2F coregulates an essential HSF developmental program that is distinct from the heat-shock response

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Transcription factors GAF and HSF act at distinct regulatory steps to modulate stress-induced gene activation

29 September 2018

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Small heat shock proteins mediate cell-autonomous and -nonautonomous protection in a Drosophila model for environmental-stress-induced degeneration.

29 September 2018

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Defining the Essential Function of Yeast Hsf1 Reveals a Compact Transcriptional Program for Maintaining Eukaryotic Proteostasis

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Mammalian Heat Shock Response and Mechanisms Underlying Its Genome-wide Transcriptional Regulation

29 September 2018

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29 September 2018

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HSF-1 activates the ubiquitin proteasome system to promote non-apoptotic developmental cell death in C. elegans.

29 September 2018

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Failure of RQC machinery causes protein aggregation and proteotoxic stress.

29 September 2018

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NEDD4-mediated HSF1 degradation underlies α-synucleinopathy

29 September 2018

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Direct link between metabolic regulation and the heat-shock response through the transcriptional regulator PGC-1α.

29 September 2018

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Celastrol Protects against Obesity and Metabolic Dysfunction through Activation of a HSF1-PGC1α Transcriptional Axis.

29 September 2018

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Heterotypic Signals from Neural HSF-1 Separate Thermotolerance from Longevity.

29 September 2018

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Repression of the Heat Shock Response Is a Programmed Event at the Onset of Reproduction

29 September 2018

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The biology of proteostasis in aging and disease

29 September 2018

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FBXW7 modulates cellular stress response and metastatic potential through HSF1 post-translational modification

29 September 2018

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Lysine deacetylases regulate the heat shock response including the age-associated impairment of HSF1.

29 September 2018

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MEK guards proteome stability and inhibits tumor-suppressive amyloidogenesis via HSF1.

29 September 2018

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Neuronal serotonin release triggers the heat shock response in C. elegans in the absence of temperature increase

29 September 2018

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A direct regulatory interaction between chaperonin TRiC and stress-responsive transcription factor HSF1.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5696061

Suppression of the HSF1-mediated proteotoxic stress response by the metabolic stress sensor AMPK

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5696061

DAPK-HSF1 interaction as a positive-feedback mechanism stimulating TNF-induced apoptosis in colorectal cancer cells

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5696061

The reprogramming of tumor stroma by HSF1 is a potent enabler of malignancy

29 September 2018

1 reference

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Hsp90 chaperone inhibitor 17-AAG attenuates Aβ-induced synaptic toxicity and memory impairment

29 September 2018

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Tight coordination of protein translation and HSF1 activation supports the anabolic malignant state

29 September 2018

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29 September 2018

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Huntington's disease: underlying molecular mechanisms and emerging concepts

29 September 2018

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Regulation of organismal proteostasis by transcellular chaperone signaling

29 September 2018

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Germline stem cell arrest inhibits the collapse of somatic proteostasis early in Caenorhabditis elegans adulthood.

29 September 2018

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Identification of a tissue-selective heat shock response regulatory network

29 September 2018

1 reference

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A ribosome-bound quality control complex triggers degradation of nascent peptides and signals translation stress

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5696061

Loss of tumor suppressor NF1 activates HSF1 to promote carcinogenesis

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5696061

HSF1 drives a transcriptional program distinct from heat shock to support highly malignant human cancers

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5696061

Heat shock factor 1 is inactivated by amino acid deprivation

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5696061

mTOR is essential for the proteotoxic stress response, HSF1 activation and heat shock protein synthesis

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5696061

Tumor suppressor functions of FBW7 in cancer development and progression

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5696061

Heat shock transcription factor 1 as a therapeutic target in neurodegenerative diseases

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5696061

Negative elongation factor accelerates the rate at which heat shock genes are shut off by facilitating dissociation of heat shock factor

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5696061

Identification of heat shock factor 1 molecular and cellular targets during embryonic and adult female meiosis

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5696061

Heat shock transcription factor 1 localizes to sex chromatin during meiotic repression.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5696061

Heat shock factors: integrators of cell stress, development and lifespan.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5696061

AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5696061

Defining mechanisms that regulate RNA polymerase II transcription in vivo

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5696061

Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5696061

Stress-inducible regulation of heat shock factor 1 by the deacetylase SIRT1

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5696061

Regulation of the cellular heat shock response in Caenorhabditis elegans by thermosensory neurons

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5696061

P-TEFb is critical for the maturation of RNA polymerase II into productive elongation in vivo

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5696061

Heat shock factor 1 is a powerful multifaceted modifier of carcinogenesis

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5696061

Opposing activities protect against age-onset proteotoxicity

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5696061

Regulation of longevity in Caenorhabditis elegans by heat shock factor and molecular chaperones

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5696061

Regulation of Aging and Age-Related Disease by DAF-16 and Heat-Shock Factor

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5696061

Evidence for a mechanism of repression of heat shock factor 1 transcriptional activity by a multichaperone complex

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5696061

Mediator, not holoenzyme, is directly recruited to the heat shock promoter by HSF upon heat shock

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5696061

Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5696061

Multiple functions of Drosophila heat shock transcription factor in vivo

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5696061

Repression of human heat shock factor 1 activity at control temperature by phosphorylation

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5696061

Sequential phosphorylation by mitogen-activated protein kinase and glycogen synthase kinase 3 represses transcriptional activation by heat shock factor-1

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5696061

Purification and properties of an ATP-dependent nucleosome remodeling factor.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5696061

Interplay of Acetyltransferase EP300 and the Proteasome System in Regulating Heat Shock Transcription Factor 1

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5696061

Maternal effect of Hsf1 on reproductive success

1 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28890254

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.TCB.2017.08.002

1 reference

5 February 2018

0 references

1 reference

5 February 2018