(Q37651883)

21 August 2017

Abnormal degradation of the neuronal stress-protective transcription factor HSF1 in Huntington's disease (English)

1 reference

21 August 2017

0 references

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28194040%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Cagla Eroglu

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28194040%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

author name string

Rocio Gomez-Pastor

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28194040%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Eileen T Burchfiel

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28194040%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Daniel W Neef

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28194040%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Alex M Jaeger

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28194040%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Elisa Cabiscol

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28194040%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Argenia Doss

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28194040%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Alejandro Aballay

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28194040%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Donald C Lo

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28194040%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Sergey S Akimov

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28194040%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Dennis J Thiele

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28194040%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Christopher A Ross

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28194040%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

language of work or name

English

0 references

publication date

13 February 2017

1 reference

21 August 2017

Nature Communications

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28194040%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28194040%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

page(s)

14405

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28194040%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

11 June 2020

copyright license

start time

13 February 2017

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5316841/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/ncomms14405

0 references

cites work

Increased occurrence of protein kinase CK2 in astrocytes in Alzheimer's disease pathology.

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PPAR-δ is repressed in Huntington's disease, is required for normal neuronal function and can be targeted therapeutically

23 August 2017

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NEDD4-mediated HSF1 degradation underlies α-synucleinopathy

23 August 2017

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FBXW7 modulates cellular stress response and metastatic potential through HSF1 post-translational modification

23 August 2017

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Altered excitatory and inhibitory inputs to striatal medium-sized spiny neurons and cortical pyramidal neurons in the Q175 mouse model of Huntington's disease

23 August 2017

1 reference

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A direct regulatory interaction between chaperonin TRiC and stress-responsive transcription factor HSF1.

23 August 2017

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Skeletal muscle pathology in Huntington's disease

23 August 2017

1 reference

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Rapid Golgi analysis method for efficient and unbiased classification of dendritic spines

23 August 2017

1 reference

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Huntingtin is required for normal excitatory synapse development in cortical and striatal circuits

23 August 2017

1 reference

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Hsp90 chaperone inhibitor 17-AAG attenuates Aβ-induced synaptic toxicity and memory impairment

23 August 2017

1 reference

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23 August 2017

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Loss of corticostriatal and thalamostriatal synaptic terminals precedes striatal projection neuron pathology in heterozygous Q140 Huntington's disease mice

23 August 2017

1 reference

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Poly-glutamine expanded huntingtin dramatically alters the genome wide binding of HSF1.

23 August 2017

1 reference

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Comprehensive behavioral and molecular characterization of a new knock-in mouse model of Huntington's disease: zQ175.

23 August 2017

1 reference

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Impaired heat shock response in cells expressing full-length polyglutamine-expanded huntingtin

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316841

Heat shock transcription factor 1 as a therapeutic target in neurodegenerative diseases

23 August 2017

1 reference

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Altered chromatin architecture underlies progressive impairment of the heat shock response in mouse models of Huntington disease

23 August 2017

1 reference

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Molecular chaperones in protein folding and proteostasis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316841

Regulation of HSF1 function in the heat stress response: implications in aging and disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316841

Deciphering human heat shock transcription factor 1 regulation via post-translational modification in yeast

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316841

Heat shock factor 1 ameliorates proteotoxicity in cooperation with the transcription factor NFAT.

23 August 2017

1 reference

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Heat shock factors: integrators of cell stress, development and lifespan.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316841

Modulation of heat shock transcription factor 1 as a therapeutic target for small molecule intervention in neurodegenerative disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316841

Huntington's disease: the current state of research with peripheral tissues.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316841

Adapting proteostasis for disease intervention

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316841

Ctip2 controls the differentiation of medium spiny neurons and the establishment of the cellular architecture of the striatum

23 August 2017

1 reference

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Role of brain-derived neurotrophic factor in Huntington's disease

23 August 2017

1 reference

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The induction levels of heat shock protein 70 differentiate the vulnerabilities to mutant huntingtin among neuronal subtypes

23 August 2017

1 reference

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Heat shock factor 1 as a coordinator of stress and developmental pathways

23 August 2017

1 reference

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Regional and cellular gene expression changes in human Huntington's disease brain

23 August 2017

1 reference

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Huntingtin and the molecular pathogenesis of Huntington's disease. Fourth in molecular medicine review series

23 August 2017

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Phosphorylation of serine 303 is a prerequisite for the stress-inducible SUMO modification of heat shock factor 1

23 August 2017

1 reference

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Protein kinase CK2: structure, regulation and role in cellular decisions of life and death

23 August 2017

1 reference

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Protein kinase CK2: a challenge to canons

23 August 2017

1 reference

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Evidence for a mechanism of repression of heat shock factor 1 transcriptional activity by a multichaperone complex

23 August 2017

1 reference

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Effects of heat shock, heat shock protein 40 (HDJ-2), and proteasome inhibition on protein aggregation in cellular models of Huntington's disease

23 August 2017

1 reference

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Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316841

Repression of human heat shock factor 1 activity at control temperature by phosphorylation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316841

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316841

A synthetic heat-shock promoter element confers heat-inducibility on the herpes simplex virus thymidine kinase gene

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316841

Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316841

Casein kinase II alteration precedes tau accumulation in tangle formation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316841

The Biology of Huntingtin.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316841

Dexamethasone induces heat shock response and slows down disease progression in mouse and fly models of Huntington's disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316841

Hormesis, cellular stress response and vitagenes as critical determinants in aging and longevity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316841

Kinase inhibitors modulate huntingtin cell localization and toxicity.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316841

17-AAG increases autophagic removal of mutant androgen receptor in spinal and bulbar muscular atrophy.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316841

Mutant Huntingtin reduces HSP70 expression through the sequestration of NF-Y transcription factor.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316841

Active HSF1 significantly suppresses polyglutamine aggregate formation in cellular and mouse models

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316841

Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntingtin

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316841

Transcriptional activity of heat shock factor 1 at 37 degrees C is repressed through phosphorylation on two distinct serine residues by glycogen synthase kinase 3 and protein kinases Calpha and Czeta

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316841

Celastrol Protects against Obesity and Metabolic Dysfunction through Activation of a HSF1-PGC1α Transcriptional Axis.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316841

Increased heat shock transcription factor 1 in the cerebellum reverses the deficiency of Purkinje cells in Alzheimer's disease.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316841

Heat shock factor-1 influences pathological lesion distribution of polyglutamine-induced neurodegeneration.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316841

Induced pluripotent stem cells from patients with Huntington's disease show CAG-repeat-expansion-associated phenotypes

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316841

1 September 2018

Huntington's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316841

Proteomic and oxidative stress analysis in human brain samples of Huntington disease.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316841

Protective up-regulation of CK2 by mutant huntingtin in cells co-expressing NMDA receptors

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316841

Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1alpha in Huntington's disease neurodegeneration

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316841

Progressive decrease in chaperone protein levels in a mouse model of Huntington's disease and induction of stress proteins as a therapeutic approach

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316841

Inclusion formation in Huntington's disease R6/2 mouse muscle cultures

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316841

Molecular chaperones enhance the degradation of expanded polyglutamine repeat androgen receptor in a cellular model of spinal and bulbar muscular atrophy

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316841

Geldanamycin activates a heat shock response and inhibits huntingtin aggregation in a cell culture model of Huntington's disease

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316841

Mechanisms of chaperone suppression of polyglutamine disease: selectivity, synergy and modulation of protein solubility in Drosophila.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316841

Decreased expression of striatal signaling genes in a mouse model of Huntington's disease

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316841

Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316841

Interplay of Acetyltransferase EP300 and the Proteasome System in Regulating Heat Shock Transcription Factor 1

1 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCOMMS14405

The role of heat shock protein (hsp70) in dendritic cell maturation: hsp70 induces the maturation of immature dendritic cells but reduces DC differentiation from monocyte precursors

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCOMMS14405

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NCOMMS14405

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28194040%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

11 June 2020

ADS bibcode

2017NatCo...814405G

0 references

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28194040%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

PubMed publication ID

28194040

1 reference