(Q48188782)

9 February 2018

title

Heat shock factor-1 influences pathological lesion distribution of polyglutamine-induced neurodegeneration. (English)

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9 February 2018

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3

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9 February 2018

Gen Sobue

16

object named as

Gen Sobue

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9 February 2018

Naohide Kondo

1

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9 February 2018

Masahisa Katsuno

2

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9 February 2018

Makoto Minamiyama

4

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9 February 2018

Hideki Doi

5

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9 February 2018

Shinjiro Matsumoto

6

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9 February 2018

Yu Miyazaki

7

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9 February 2018

Madoka Iida

8

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9 February 2018

Genki Tohnai

9

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9 February 2018

Hideaki Nakatsuji

10

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9 February 2018

Shinsuke Ishigaki

11

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9 February 2018

Yusuke Fujioka

12

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9 February 2018

Hirohisa Watanabe

13

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9 February 2018

Fumiaki Tanaka

14

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9 February 2018

Akira Nakai

15

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9 February 2018

language of work or name

English

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publication date

1 January 2013

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9 February 2018

published in

Nature Communications

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9 February 2018

volume

4

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9 February 2018

page(s)

1405

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9 February 2018

https://scigraph.springernature.com/pub.10.1038/ncomms2417

exact match

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cites work

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Role of heat shock proteins during polyglutamine neurodegeneration: mechanisms and hypothesis

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Modulation of neurodegeneration by molecular chaperones

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Suppression of Alzheimer's disease-related phenotypes by expression of heat shock protein 70 in mice.

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Exogenous delivery of heat shock protein 70 increases lifespan in a mouse model of amyotrophic lateral sclerosis.

21 January 2018

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Hsp70 and Hsp40 attenuate formation of spherical and annular polyglutamine oligomers by partitioning monomer

21 January 2018

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Molecular chaperones enhance the degradation of expanded polyglutamine repeat androgen receptor in a cellular model of spinal and bulbar muscular atrophy

21 January 2018

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Genetic modulation of polyglutamine toxicity by protein conjugation pathways in Drosophila

21 January 2018

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Pharmacological induction of heat-shock proteins alleviates polyglutamine-mediated motor neuron disease

21 January 2018

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Regulation of HSF1 function in the heat stress response: implications in aging and disease

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Spinocerebellar ataxia type 7 (SCA7): a neurodegenerative disorder with neuronal intranuclear inclusions.

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Polyglutamine disease: recent advances in the neuropathology of dentatorubral-pallidoluysian atrophy

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Intra- and intermolecular beta-pleated sheet formation in glutamine-repeat inserted myoglobin as a model for polyglutamine diseases

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Interaction between mutant ataxin-1 and PQBP-1 affects transcription and cell death

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Rhes, a striatal specific protein, mediates mutant-huntingtin cytotoxicity

21 January 2018

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The induction levels of heat shock protein 70 differentiate the vulnerabilities to mutant huntingtin among neuronal subtypes

21 January 2018

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Mutant Huntingtin reduces HSP70 expression through the sequestration of NF-Y transcription factor.

21 January 2018

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Widespread nuclear and cytoplasmic accumulation of mutant androgen receptor in SBMA patients.

21 January 2018

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Widespread occurrence of intranuclear atrophin-1 accumulation in the central nervous system neurons of patients with dentatorubral-pallidoluysian atrophy

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Sodium butyrate ameliorates phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy

21 January 2018

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Mitochondrial abnormalities in spinal and bulbar muscular atrophy

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Testosterone reduction prevents phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy

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Androgen-dependent neurodegeneration by polyglutamine-expanded human androgen receptor in Drosophila.

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Leuprorelin rescues polyglutamine-dependent phenotypes in a transgenic mouse model of spinal and bulbar muscular atrophy

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Castration restores function and neurofilament alterations of aged symptomatic males in a transgenic mouse model of spinal and bulbar muscular atrophy.

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Progressive proximal spinal and bulbar muscular atrophy of late onset. A sex-linked recessive trait

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Trinucleotide Repeat Disorders

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Androgen receptor mRNA with increased size of tandem CAG repeat is widely expressed in the neural and nonneural tissues of X-linked recessive bulbospinal neuronopathy

21 January 2018

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Heat shock factor 1 ameliorates proteotoxicity in cooperation with the transcription factor NFAT.

21 January 2018

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Cooperative and competitive protein interactions at the hsp70 promoter.

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Xenopus NF-Y pre-sets chromatin to potentiate p300 and acetylation-responsive transcription from the Xenopus hsp70 promoter in vivo

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Sp1 is involved in Akt-mediated induction of VEGF expression through an HIF-1-independent mechanism.

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Active HSF1 significantly suppresses polyglutamine aggregate formation in cellular and mouse models

21 January 2018

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CHIP overexpression reduces mutant androgen receptor protein and ameliorates phenotypes of the spinal and bulbar muscular atrophy transgenic mouse model.

21 January 2018

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17-AAG, an Hsp90 inhibitor, ameliorates polyglutamine-mediated motor neuron degeneration

21 January 2018

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Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy

21 January 2018

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Induction of molecular chaperones as a therapeutic strategy for the polyglutamine diseases

21 January 2018

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Analysis of heat shock transcription factor for suppression of polyglutamine toxicity.

21 January 2018

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'Green mice' as a source of ubiquitous green cells.

21 January 2018

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17-DMAG ameliorates polyglutamine-mediated motor neuron degeneration through well-preserved proteasome function in an SBMA model mouse

21 January 2018

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Valproic acid induces functional heat-shock protein 70 via Class I histone deacetylase inhibition in cortical neurons: a potential role of Sp1 acetylation

21 January 2018

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Mutant huntingtin fragment selectively suppresses Brn-2 POU domain transcription factor to mediate hypothalamic cell dysfunction

21 January 2018

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Regulation of Aging and Age-Related Disease by DAF-16 and Heat-Shock Factor

21 January 2018

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A versatile viral system for expression and depletion of proteins in mammalian cells

21 January 2018

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S6 kinase inactivation impairs growth and translational target phosphorylation in muscle cells maintaining proper regulation of protein turnover

21 January 2018

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Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity

21 January 2018

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12 December 2020

X-linked recessive bulbospinal neuronopathy. A clinicopathological study

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12 December 2020

Stress-inducible responses and heat shock proteins: new pharmacologic targets for cytoprotection

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12 December 2020

Chaperones Hsp70 and Hsp40 suppress aggregate formation and apoptosis in cultured neuronal cells expressing truncated androgen receptor protein with expanded polyglutamine tract

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12 December 2020

Heat shock transcription factor 1 opens chromatin structure of interleukin-6 promoter to facilitate binding of an activator or a repressor

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12 December 2020

Heat shock protein 70 chaperone overexpression ameliorates phenotypes of the spinal and bulbar muscular atrophy transgenic mouse model by reducing nuclear-localized mutant androgen receptor protein

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12 December 2020

A toxic monomeric conformer of the polyglutamine protein

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12 December 2020

Identifiers

DOI

10.1038/NCOMMS2417

1 reference

9 February 2018

Dimensions Publication ID

ADS bibcode

2013NatCo...4.1405K

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9 February 2018