(Q35463880)

8 August 2017

FBXW7 modulates cellular stress response and metastatic potential through HSF1 post-translational modification (English)

1 reference

8 August 2017

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25720964%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Iraz T Aydin

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25720964%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Judy Zhong

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25720964%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Charalampos Lazaris

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25720964%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Aristotelis Tsirigos

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25720964%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Eva Hernando

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25720964%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

17

Iannis Aifantis

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25720964%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

author name string

Nikos Kourtis

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25720964%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Beatriz Aranda-Orgilles

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25720964%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Kevin Lui

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25720964%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Thomas Trimarchi

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25720964%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Farbod Darvishian

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25720964%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Christine Salvaggio

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25720964%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Kamala Bhatt

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25720964%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Emily I Chen

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25720964%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Julide T Celebi

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25720964%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Iman Osman

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25720964%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

language of work or name

1 reference

1 March 2015

1 reference

8 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25720964%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

volume

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25720964%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25720964%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

page(s)

322-332

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25720964%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/ncb3121

4 June 2020

exact match

0 references

cites work

Tumor suppression by the Fbw7 ubiquitin ligase: mechanisms and opportunities

1 reference

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The reprogramming of tumor stroma by HSF1 is a potent enabler of malignancy

12 July 2018

1 reference

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Targeting RAF kinases for cancer therapy: BRAF-mutated melanoma and beyond

12 July 2018

1 reference

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Aberrant regulation of FBW7 in cancer

12 July 2018

1 reference

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Roles of F-box proteins in cancer

12 July 2018

1 reference

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A component of the mir-17-92 polycistronic oncomir promotes oncogene-dependent apoptosis.

12 July 2018

1 reference

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Tight coordination of protein translation and HSF1 activation supports the anabolic malignant state

12 July 2018

1 reference

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The ubiquitin ligase FBXW7 modulates leukemia-initiating cell activity by regulating MYC stability

12 July 2018

1 reference

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Mechanisms and function of substrate recruitment by F-box proteins.

12 July 2018

1 reference

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Rapamycin inhibits FBXW7 loss-induced epithelial-mesenchymal transition and cancer stem cell-like characteristics in colorectal cancer cells

12 July 2018

1 reference

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Prognostic significance of Fbw7 in human melanoma and its role in cell migration

12 July 2018

1 reference

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The SCF-Fbw7 ubiquitin ligase degrades MED13 and MED13L and regulates CDK8 module association with Mediator

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401662

Loss of tumor suppressor NF1 activates HSF1 to promote carcinogenesis

12 July 2018

1 reference

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HSF1 drives a transcriptional program distinct from heat shock to support highly malignant human cancers

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401662

Fbxw7α- and GSK3-mediated degradation of p100 is a pro-survival mechanism in multiple myeloma

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401662

Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia

12 July 2018

1 reference

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Using the heat-shock response to discover anticancer compounds that target protein homeostasis

12 July 2018

1 reference

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High levels of nuclear heat-shock factor 1 (HSF1) are associated with poor prognosis in breast cancer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401662

High-throughput illumina strand-specific RNA sequencing library preparation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401662

Promotion of heat shock factor Hsf1 degradation via adaptor protein filamin A-interacting protein 1-like (FILIP-1L).

12 July 2018

1 reference

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Proinvasion metastasis drivers in early-stage melanoma are oncogenes

12 July 2018

1 reference

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Heat shock transcription factor 1 is a key determinant of HCC development by regulating hepatic steatosis and metabolic syndrome

12 July 2018

1 reference

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Overcoming trastuzumab resistance in breast cancer by targeting dysregulated glucose metabolism.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401662

Regulation of HSF1 function in the heat stress response: implications in aging and disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401662

SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction

12 July 2018

1 reference

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Heat shock factors: integrators of cell stress, development and lifespan.

12 July 2018

1 reference

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Heat-shock transcription factor HSF1 has a critical role in human epidermal growth factor receptor-2-induced cellular transformation and tumorigenesis

12 July 2018

1 reference

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Integrative genome comparison of primary and metastatic melanomas

12 July 2018

1 reference

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12 July 2018

1 reference

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Loss of FBXW7, a cell cycle regulating gene, in colorectal cancer: clinical significance

12 July 2018

1 reference

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Principles of cancer therapy: oncogene and non-oncogene addiction

12 July 2018

1 reference

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Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

12 July 2018

1 reference

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Stress-inducible regulation of heat shock factor 1 by the deacetylase SIRT1

12 July 2018

1 reference

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Model-based analysis of ChIP-Seq (MACS)

12 July 2018

1 reference

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Control of hematopoietic stem cell quiescence by the E3 ubiquitin ligase Fbw7

12 July 2018

1 reference

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The gene expression profiles of primary and metastatic melanoma yields a transition point of tumor progression and metastasis

12 July 2018

1 reference

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Heat shock factor 1 is a powerful multifaceted modifier of carcinogenesis

12 July 2018

1 reference

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Non-oncogene addiction and the stress phenotype of cancer cells

12 July 2018

1 reference

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Structure of a Fbw7-Skp1-cyclin E complex: multisite-phosphorylated substrate recognition by SCF ubiquitin ligases

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401662

HSP90 and the chaperoning of cancer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401662

Heat shock response modulators as therapeutic tools for diseases of protein conformation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401662

Interactions between extracellular signal-regulated protein kinase 1, 14-3-3epsilon, and heat shock factor 1 during stress

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401662

The International Protein Index: an integrated database for proteomics experiments

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401662

The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401662

Inactivation of hCDC4 can cause chromosomal instability

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401662

Phosphorylation of serine 303 is a prerequisite for the stress-inducible SUMO modification of heat shock factor 1

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401662

DTASelect and Contrast: tools for assembling and comparing protein identifications from shotgun proteomics

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401662

Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401662

The Notch intracellular domain is ubiquitinated and negatively regulated by the mammalian Sel-10 homolog

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401662

Role of the heat shock response and molecular chaperones in oncogenesis and cell death

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401662

Glycogen synthase kinase 3beta and extracellular signal-regulated kinase inactivate heat shock transcription factor 1 by facilitating the disappearance of transcriptionally active granules after heat shock

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401662

Negative regulation of the heat shock transcriptional response by HSBP1

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401662

Molecular chaperones as HSF1-specific transcriptional repressors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401662

Repression of the heat shock factor 1 transcriptional activation domain is modulated by constitutive phosphorylation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401662

Repression of human heat shock factor 1 activity at control temperature by phosphorylation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401662

Sequential phosphorylation by mitogen-activated protein kinase and glycogen synthase kinase 3 represses transcriptional activation by heat shock factor-1

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401662

Method to correlate tandem mass spectra of modified peptides to amino acid sequences in the protein database

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401662

The human heat shock protein hsp70 interacts with HSF, the transcription factor that regulates heat shock gene expression

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401662

GenomicTools: a computational platform for developing high-throughput analytics in genomics.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401662

Detection of protein ubiquitination

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401662

p53-Altered FBXW7 expression determines poor prognosis in gastric cancer cases.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401662

FBXW7/hCDC4 is a general tumor suppressor in human cancer.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401662

FBXW7/hCDC4 controls glioma cell proliferation in vitro and is a prognostic marker for survival in glioblastoma patients

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401662

A regulatory upstream promoter element in the Drosophila hsp 70 heat-shock gene.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401662

Interplay of Acetyltransferase EP300 and the Proteasome System in Regulating Heat Shock Transcription Factor 1

26 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCB3121

Selective suppression of lymphomas by functional loss of Hsf1 in a p53-deficient mouse model for spontaneous tumors

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25720964

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Inhibiting the transcription factor HSF1 as an anticancer strategy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25720964

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Glycogen synthase kinase 3beta negatively regulates both DNA-binding and transcriptional activities of heat shock factor 1

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25720964

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCB3121

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25720964%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

4 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25720964%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25720964%20AND%20SRC:MED&resulttype=core&format=json