(Q35742745)

10 August 2017

Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia (English)

1 reference

10 August 2017

1 reference

lymphoblastic leukemia

1 reference

inferred from title

author

Pieter Van Vlierberghe

3

María Domínguez Castellano

Pieter Van Vlierberghe

0 references

Maria Dominguez

27

0 references

Aristotelis Tsirigos

Aristotelis Tsirigos

2

0 references

Kim De Keersmaecker

Kim De Keersmaecker

14

0 references

Francoise Pflumio

Francoise Pflumio

26

0 references

Raúl Rabadán

Raul Rabadan

23

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Vanina da Ros

Vanina da Ros

8

0 references

Elisabeth Paietta

20

Elisabeth Paietta

1 reference

10 August 2017

29

Iannis Aifantis

1 reference

10 August 2017

Panagiotis Ntziachristos

1

1 reference

10 August 2017

Jelena Nedjic

4

1 reference

10 August 2017

Thomas Trimarchi

5

1 reference

10 August 2017

Maria Sol Flaherty

6

1 reference

10 August 2017

Dolors Ferres-Marco

7

1 reference

10 August 2017

Zuojian Tang

9

1 reference

10 August 2017

Jasmin Siegle

10

1 reference

10 August 2017

Patrik Asp

11

1 reference

10 August 2017

Michael Hadler

12

1 reference

10 August 2017

Isaura Rigo

13

1 reference

10 August 2017

Jay Patel

15

1 reference

10 August 2017

Tien Huynh

16

1 reference

10 August 2017

Filippo Utro

17

1 reference

10 August 2017

Sandrine Poglio

18

1 reference

10 August 2017

Jeremy B Samon

19

1 reference

10 August 2017

Janis Racevskis

21

1 reference

10 August 2017

Jacob M Rowe

22

1 reference

10 August 2017

Ross L Levine

24

1 reference

10 August 2017

Stuart Brown

25

1 reference

10 August 2017

Adolfo Ferrando

28

1 reference

10 August 2017

language of work or name

English

0 references

publication date

6 February 2012

1 reference

10 August 2017

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10 August 2017

18

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10 August 2017

298-301

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10 August 2017

2

1 reference

https://scigraph.springernature.com/pub.10.1038/nm.2651

10 August 2017

0 references

cites work

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Cancer epigenetics reaches mainstream oncology

12 July 2018

1 reference

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Aberrations of EZH2 in cancer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274628

The Polycomb complex PRC2 and its mark in life

12 July 2018

1 reference

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Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation

12 July 2018

1 reference

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A unique chromatin signature uncovers early developmental enhancers in humans

12 July 2018

1 reference

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Notch signalling in T-cell lymphoblastic leukaemia/lymphoma and other haematological malignancies

12 July 2018

1 reference

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Molecular pathogenesis and targeted therapies for NOTCH1-induced T-cell acute lymphoblastic leukemia

12 July 2018

1 reference

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Decision checkpoints in the thymus

12 July 2018

1 reference

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Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes

12 July 2018

1 reference

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Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders

12 July 2018

1 reference

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Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274628

c-Myc regulates transcriptional pause release

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274628

Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin

12 July 2018

1 reference

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Fast and accurate long-read alignment with Burrows-Wheeler transform

12 July 2018

1 reference

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Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274628

The future therapeutic potential of histone demethylases: A critical analysis.

12 July 2018

1 reference

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CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274628

The context and potential of epigenetics in oncology

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274628

H2AZ is enriched at polycomb complex target genes in ES cells and is necessary for lineage commitment

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274628

Model-based analysis of ChIP-Seq (MACS)

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274628

Molecular pathogenesis of T-cell leukaemia and lymphoma

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274628

NOTCH1 extracellular juxtamembrane expansion mutations in T-ALL.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274628

Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274628

The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274628

A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274628

High-resolution profiling of histone methylations in the human genome

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274628

NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274628

Myc is a Notch1 transcriptional target and a requisite for Notch1-induced mammary tumorigenesis in mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274628

Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274628

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274628

SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274628

Polycomb, epigenomes, and control of cell identity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274628

Quantitative noise analysis for gene expression microarray experiments

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274628

Active genes are tri-methylated at K4 of histone H3

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274628

GenomicTools: a computational platform for developing high-throughput analytics in genomics.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274628

Hes1 is a critical but context-dependent mediator of canonical Notch signaling in lymphocyte development and transformation.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274628

Epigenetic silencers and Notch collaborate to promote malignant tumours by Rb silencing.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274628

Transcription-linked acetylation by Gcn5p of histones H3 and H4 at specific lysines

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22237151

12 December 2020

inferred from PubMed ID database lookup

Expression of CD34 and CD7 on human T-cell acute lymphoblastic leukemia discriminates functionally heterogeneous cell populations

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNM.2651

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NM.2651

1 reference

release_znsvu644njfrhdtfus6al5r2ly

10 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/znsvu644njfrhdtfus6al5r2ly

24 November 2022

mapped directly with Wikidata item

PMCID

3274628

1 reference

10 August 2017

1 reference