(Q47870283)

6 February 2018

title

Molecular interaction maps as information organizers and simulation guides. (English)

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6 February 2018

main subject

molecular interaction

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Kurt W. Kohn

1

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6 February 2018

publication date

1 March 2001

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6 February 2018

published in

Chaos

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6 February 2018

volume

11

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6 February 2018

page(s)

84-97

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6 February 2018

issue

1

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6 February 2018

maintained by WikiProject

WikiProject Mathematics

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cites work

Molecular interaction map of the mammalian cell cycle control and DNA repair systems

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Signaling complexes: biophysical constraints on intracellular communication.

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Complexity in biological signaling systems

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Computer-based analysis of the binding steps in protein complex formation

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Predicting temporal fluctuations in an intracellular signalling pathway.

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It's a noisy business! Genetic regulation at the nanomolar scale

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Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain

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Signaling through scaffold, anchoring, and adaptor proteins

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Crystal structures of c-Src reveal features of its autoinhibitory mechanism

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Crosstalk between the catalytic and regulatory domains allows bidirectional regulation of Src.

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Mechanism of biological synergy between cellular Src and epidermal growth factor receptor

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A phosphotyrosine displacement mechanism for activation of Src by PTPalpha

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Molecular switches in lipid rafts.

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Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases

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The regulation of E2F by pRB-family proteins

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E2F is required to prevent inappropriate S-phase entry of mammalian cells

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Interaction of Sp1 with the growth- and cell cycle-regulated transcription factor E2F

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Cell cycle-regulated association of E2F1 and Sp1 is related to their functional interaction

21 January 2018

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Inhibition of cyclin D1 kinase activity is associated with E2F-mediated inhibition of cyclin D1 promoter activity through E2F and Sp1.

21 January 2018

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Rb interacts with histone deacetylase to repress transcription

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Retinoblastoma protein recruits histone deacetylase to repress transcription

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Cellular survival: a play in three Akts

21 January 2018

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Mechanism of protein kinase B activation by insulin/insulin-like growth factor-1 revealed by specific inhibitors of phosphoinositide 3-kinase--significance for diabetes and cancer

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Domain swapping used to investigate the mechanism of protein kinase B regulation by 3-phosphoinositide-dependent protein kinase 1 and Ser473 kinase

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A dimeric 14-3-3 protein is an essential cofactor for Raf kinase activity

21 January 2018

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AKT/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositide-dependent phosphorylation

21 January 2018

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The role of phosphoinositide 3-kinase lipid products in cell function

21 January 2018

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Phosphatidylinositol phosphate kinases, a multifaceted family of signaling enzymes.

21 January 2018

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21 January 2018

Phosphoinositide kinases

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Signalling through phosphoinositide 3-kinases: the lipids take centre stage

21 January 2018

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The inositol phosphatase SHIP inhibits Akt/PKB activation in B cells

21 January 2018

1 reference

PDGF induces an early and a late wave of PI 3-kinase activity, and only the late wave is required for progression through G1.

21 January 2018

1 reference

Transmembrane Phosphoprotein Cbp Positively Regulates the Activity of the Carboxyl-terminal Src Kinase, Csk

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Structural organization of MAP-kinase signaling modules by scaffold proteins in yeast and mammals

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Identifiers

DOI

10.1063/1.1338126

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6 February 2018

PubMed ID

12779444

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6 February 2018