(Q47895566)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22508963%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

title

Pro-arrhythmogenic effects of the S140G KCNQ1 mutation in human atrial fibrillation - insights from modelling (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22508963%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference

5

1 reference

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29 January 2020

Sanjay R Kharche

1

1 reference

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29 January 2020

author name string

Ismail Adeniran

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22508963%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Jonathan Stott

3

1 reference

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29 January 2020

Phillip Law

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22508963%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Jules C Hancox

6

1 reference

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29 January 2020

Henggui Zhang

7

1 reference

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29 January 2020

language of work or name

English

0 references

publication date

16 April 2012

1 reference

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29 January 2020

published in

Journal of Physiology

1 reference

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29 January 2020

volume

590

1 reference

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29 January 2020

issue

18

1 reference

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29 January 2020

page(s)

4501-4514

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22508963%20AND%20SRC:MED&resulttype=core&format=json

A computational model to predict the effects of class I anti-arrhythmic drugs on ventricular rhythms

29 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

The S140G KCNQ1 atrial fibrillation mutation affects 'I(KS)' profile during both atrial and ventricular action potentials.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

Clinical, economic, and quality of life impact of atrial fibrillation.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

Genetics of familial atrial fibrillation

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

Augmented potassium current is a shared phenotype for two genetic defects associated with familial atrial fibrillation

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

Mutation in the S3 segment of KCNQ1 results in familial lone atrial fibrillation

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

Atrial fibrillation and congestive heart failure

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

Simulating the effects of atrial fibrillation induced electrical remodeling: a comprehensive simulation study

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

Atrial proarrhythmia due to increased inward rectifier current (I(K1)) arising from KCNJ2 mutation--a simulation study.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

Risk factors, atrial fibrillation and thromboembolic events.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

Role of potassium currents in cardiac arrhythmias

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

Mechanisms by which atrial fibrillation-associated mutations in the S1 domain of KCNQ1 slow deactivation of IKs channels

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

Cellular bases for human atrial fibrillation

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

Identification of a novel KCNQ1 mutation associated with both Jervell and Lange-Nielsen and Romano-Ward forms of long QT syndrome in a Chinese family

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

Gain of function in IKs secondary to a mutation in KCNE5 associated with atrial fibrillation

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

Pre-excited atrial fibrillation triggered by intravenous adenosine: a commonly used drug with potentially life-threatening adverse effects

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

Changes in I K, ACh single-channel activity with atrial tachycardia remodelling in canine atrial cardiomyocytes

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

KCNQ1 mutation Q147R is associated with atrial fibrillation and prolonged QT interval

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

Genes and atrial fibrillation: a new look at an old problem

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

Potassium channel gene mutations rarely cause atrial fibrillation

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

Kv1.5 channelopathy due to KCNA5 loss-of-function mutation causes human atrial fibrillation

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

Heterogeneous three-dimensional anatomical and electrophysiological model of human atria

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

26 August 2018

From molecule to malady

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

Atrial fibrillation: basic mechanisms, remodeling and triggers.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

De novo KCNQ1 mutation responsible for atrial fibrillation and short QT syndrome in utero.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

A Kir2.1 gain-of-function mutation underlies familial atrial fibrillation

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

Substrate size as a determinant of fibrillatory activity maintenance in a mathematical model of canine atrium

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

Ionic determinants of functional reentry in a 2-D model of human atrial cells during simulated chronic atrial fibrillation

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

Sodium channel mutations and susceptibility to heart failure and atrial fibrillation

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

Identification of a KCNE2 gain-of-function mutation in patients with familial atrial fibrillation

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

Parental atrial fibrillation as a risk factor for atrial fibrillation in offspring

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

Mutation in the KCNQ1 gene leading to the short QT-interval syndrome

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

Electromechanical model of excitable tissue to study reentrant cardiac arrhythmias

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

Sudden death associated with short-QT syndrome linked to mutations in HERG.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

KCNQ1 gain-of-function mutation in familial atrial fibrillation

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

New ideas about atrial fibrillation 50 years on.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

The contribution of ionic currents to changes in refractoriness of human atrial myocytes associated with chronic atrial fibrillation

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

Gap junctional remodeling in relation to stabilization of atrial fibrillation in the goat

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

Gap junctions in cardiovascular disease

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

Basic mechanisms of atrial fibrillation--very new insights into very old ideas

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

Cardiac electrical restitution properties and stability of reentrant spiral waves: a simulation study.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

Ionic mechanisms underlying human atrial action potential properties: insights from a mathematical model.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

Rapid inactivation determines the rectification and [K+]o dependence of the rapid component of the delayed rectifier K+ current in cardiac cells.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

Unidirectional block and reentry of cardiac excitation: a model study.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3477754

Vagal effects on the occurrence of focal atrial fibrillation originating from the pulmonary veins

26 August 2018

1 reference

12 December 2020

Action potential duration restitution kinetics in human atrial fibrillation

1 reference

12 December 2020

Rate-dependent changes in atrial action potential duration after short- duration rapid atrial pacing in humans

1 reference

12 December 2020

The Visible Human Project

1 reference

12 December 2020

Burden of atrial fibrillation

1 reference

12 December 2020

Blood pressure control and the reduction of left atrial overload is essential for controlling atrial fibrillation

1 reference

12 December 2020

Ionic mechanisms of electrical remodeling in human atrial fibrillation

1 reference

12 December 2020

Imaging outcomes from the National Library of Medicine's Visible Human Project

1 reference

12 December 2020

Simulation of two-dimensional anisotropic cardiac reentry: effects of the wavelength on the reentry characteristics

1 reference

12 December 2020

The Vulnerable Window for Unidirectional Block in Cardiac Tissue:

1 reference

12 December 2020

Role of up-regulation of IK1 in action potential shortening associated with atrial fibrillation in humans

1 reference

12 December 2020

Stretch-sensitive KCNQ1 mutation A link between genetic and environmental factors in the pathogenesis of atrial fibrillation?

1 reference

12 December 2020

Human KCNQ1 S140G mutation is associated with atrioventricular blocks

1 reference

12 December 2020

Repolarisation and vulnerability to re-entry in the human heart with short QT syndrome arising from KCNQ1 mutation--a simulation study

1 reference

12 December 2020

Sinus rhythm restoration after atrial fibrillation: the clinical value of N-terminal pro-BNP measurements

1 reference

12 December 2020

Action potential remodeling in the human right atrium with chronic lone atrial fibrillation

1 reference

12 December 2020

10.1113/JPHYSIOL.2012.229146

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22508963%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

PMC publication ID

3477754

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22508963%20AND%20SRC:MED&resulttype=core&format=json