(Q47897710)

http://europepmc.org/abstract/MED/28846099

6 February 2018

title

GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand. (English)

1 reference

http://europepmc.org/abstract/MED/28846099

6 February 2018

0 references

1 reference

GDNF family receptor alpha like

1 reference

Growth differentiation factor 15

1 reference

positive regulation of protein kinase B signaling

1 reference

GDNF family receptor alpha like

1 reference

Ret proto-oncogene

1 reference

author

Chih-Chuan Chang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28846099%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Haisun Zhu

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28846099%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Anne Bugge

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28846099%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Haibin Chen

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28846099%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Xun Li

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28846099%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Xiang Gao

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28846099%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Sebastian Beck Jørgensen

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28846099%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

author name string

Linda Yang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28846099%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Zhe Sun

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28846099%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Dennis Madsen

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28846099%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Søren B Padkjær

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28846099%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Xiaoai Wu

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28846099%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Tao Huang

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28846099%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Karin Hultman

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28846099%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Sarah J Paulsen

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28846099%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Jishu Wang

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28846099%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Jane Boesen Frantzen

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28846099%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Per Nørgaard

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28846099%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Jacob Fuglsbjerg Jeppesen

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28846099%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Zhiru Yang

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28846099%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Anna Secher

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28846099%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Linu Mary John

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28846099%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Bing Shan

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28846099%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Zhenhua He

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28846099%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Jing Su

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28846099%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Kristian T Hansen

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28846099%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Wei Yang

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28846099%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

language of work or name

English

0 references

publication date

28 August 2017

1 reference

http://europepmc.org/abstract/MED/28846099

6 February 2018

published in

Nature Medicine

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28846099%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

volume

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28846099%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

page(s)

1158-1166

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28846099%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28846099%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nm.4394

10 June 2020

exact match

0 references

cites work

Tumor-induced anorexia and weight loss are mediated by the TGF-beta superfamily cytokine MIC-1.

1 reference

Macrophage inhibitory cytokine 1 (MIC-1/GDF15) decreases food intake, body weight and improves glucose tolerance in mice on normal & obesogenic diets

21 January 2018

1 reference

Serum Levels of Human MIC-1/GDF15 Vary in a Diurnal Pattern, Do Not Display a Profile Suggestive of a Satiety Factor and Are Related to BMI.

21 January 2018

1 reference

The anorectic actions of the TGFβ cytokine MIC-1/GDF15 require an intact brainstem area postrema and nucleus of the solitary tract

21 January 2018

1 reference

Characterization of the rat, mouse, and human genes of growth/differentiation factor-15/macrophage inhibiting cytokine-1 (GDF-15/MIC-1).

21 January 2018

1 reference

MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-beta superfamily

21 January 2018

1 reference

Functions of the TGFbeta superfamily in human embryonic stem cells

21 January 2018

1 reference

Transforming growth factor-beta-related proteins: an ancestral and widespread superfamily of cytokines in metazoans

21 January 2018

1 reference

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21 January 2018

1 reference

Evolution of the GDNF family ligands and receptors.

21 January 2018

1 reference

GDF-15 inhibits integrin activation and mouse neutrophil recruitment through the ALK-5/TGF-βRII heterodimer.

21 January 2018

1 reference

Growth differentiation factor-15 promotes glutamate release in medial prefrontal cortex of mice through upregulation of T-type calcium channels

21 January 2018

1 reference

Identification, expression and functional characterization of the GRAL gene

21 January 2018

1 reference

Epitope mapping of the transforming growth factor-beta superfamily protein, macrophage inhibitory cytokine-1 (MIC-1): identification of at least five distinct epitope specificities

21 January 2018

1 reference

The GDNF family ligands and receptors - implications for neural development

21 January 2018

1 reference

The GDNF family: signalling, biological functions and therapeutic value

21 January 2018

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GDNF family neurotrophic factor signaling: four masters, one servant?

21 January 2018

1 reference

The structure of GFRalpha1 domain 3 reveals new insights into GDNF binding and RET activation

21 January 2018

1 reference

Determinants of ligand binding specificity in the glial cell line-derived neurotrophic factor family receptor alpha S.

21 January 2018

1 reference

Characterization of a multicomponent receptor for GDNF.

21 January 2018

1 reference

Genetic deletion of growth differentiation factor 15 augments renal damage in both type 1 and type 2 models of diabetes

21 January 2018

1 reference

The transforming growth factor-beta superfamily member growth-differentiation factor-15 protects the heart from ischemia/reperfusion injury

21 January 2018

1 reference

GDF15 contributes to radiation-induced senescence through the ROS-mediated p16 pathway in human endothelial cells

21 January 2018

1 reference

Phosphotyrosine 1062 is critical for the in vivo activity of the Ret9 receptor tyrosine kinase isoform

21 January 2018

1 reference

Progressive postnatal motoneuron loss in mice lacking GDF-15.

21 January 2018

1 reference

TGF-b superfamily cytokine MIC-1/GDF15 is a physiological appetite and body weight regulator

21 January 2018

1 reference

Glial cell line-derived neurotrophic factor protects against high-fat diet-induced obesity.

21 January 2018

1 reference

Brain-derived neurotrophic factor (BDNF) and food intake regulation: a minireview.

21 January 2018

1 reference

Tissue distribution of Ret, GFRalpha-1, GFRalpha-2 and GFRalpha-3 receptors in the human brainstem at fetal, neonatal and adult age.

21 January 2018

1 reference

Distribution of GDNF family receptor alpha3 and RET in rat and human non-neural tissues

21 January 2018

1 reference

NAG-1/GDF-15 prevents obesity by increasing thermogenesis, lipolysis and oxidative metabolism

21 January 2018

1 reference

7 January 2021

inferred from DOI database lookup

Intracellular Cl activity: evidence of dual mechanisms of cl absorption in sweat duct.

1 reference

7 January 2021

inferred from DOI database lookup

Volume regulation in NIH/3T3 cells not expressing P-glycoprotein. II. Chloride and amino acid fluxes

1 reference

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A method for selective section of vagal afferent or efferent axons in the rat.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28846099

12 December 2020

inferred from PubMed ID database lookup

Vagal afferent and efferent contributions to the inhibition of food intake by cholecystokinin

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28846099

12 December 2020

inferred from PubMed ID database lookup

Growth differentiation factor 15 acts anti-apoptotic and pro-hypertrophic in adult cardiomyocytes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28846099

12 December 2020