(Q47916242)

English

Cinacalcet Rectifies Hypercalcemia in a Patient With Familial Hypocalciuric Hypercalcemia Type 2 (FHH2) Caused by a Germline Loss-of-Function Gα11 Mutation.

scientific article published on 18 August 2017

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scholarly article

1 reference

Europe PubMed Central

30 June 2018

http://europepmc.org/abstract/PMC/5813271

Cinacalcet Rectifies Hypercalcemia in a Patient With Familial Hypocalciuric Hypercalcemia Type 2 (FHH2) Caused by a Germline Loss-of-Function Gα11 Mutation. (English)

1 reference

Europe PubMed Central

30 June 2018

http://europepmc.org/abstract/PMC/5813271

familial hypocalciuric hypercalcemia

1 reference

based on heuristic

inferred from title

Caroline M Gorvin

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28833550%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Fadil M. Hannan

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28833550%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Camilla Schalin-Jäntti

6

object named as

Camilla Schalin-Jantti

1 reference

Europe PubMed Central

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10 June 2020

author name string

Treena Cranston

3

1 reference

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10 June 2020

Helena Valta

4

1 reference

Europe PubMed Central

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10 June 2020

Outi Makitie

5

1 reference

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10 June 2020

Rajesh V Thakker

7

1 reference

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10 June 2020

publication date

22 September 2017

1 reference

Europe PubMed Central

30 June 2018

http://europepmc.org/abstract/PMC/5813271

Journal of Bone and Mineral Research

1 reference

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10 June 2020

33

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10 June 2020

1

1 reference

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10 June 2020

32-41

1 reference

Europe PubMed Central

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10 June 2020

Gα11 mutation in mice causes hypocalcemia rectifiable by calcilytic therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5813271

3 July 2018

Disorders of the calcium-sensing receptor and partner proteins: insights into the molecular basis of calcium homeostasis

1 reference

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3 July 2018

Cinacalcet for Symptomatic Hypercalcemia Caused by AP2S1 Mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5813271

3 July 2018

Towards a structural understanding of allosteric drugs at the human calcium-sensing receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5813271

3 July 2018

Allosteric Modulation of the Calcium-sensing Receptor Rectifies Signaling Abnormalities Associated with G-protein α-11 Mutations Causing Hypercalcemic and Hypocalcemic Disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5813271

3 July 2018

A G-protein Subunit-α11 Loss-of-Function Mutation, Thr54Met, Causes Familial Hypocalciuric Hypercalcemia Type 2 (FHH2)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5813271

3 July 2018

Distinct profiles of functional discrimination among G proteins determine the actions of G protein-coupled receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5813271

3 July 2018

Adaptor protein-2 sigma subunit mutations causing familial hypocalciuric hypercalcaemia type 3 (FHH3) demonstrate genotype-phenotype correlations, codon bias and dominant-negative effects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5813271

3 July 2018

Molecular mechanisms of phospholipase C β3 autoinhibition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5813271

3 July 2018

Mutant prolactin receptor and familial hyperprolactinemia

1 reference

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3 July 2018

Engendering biased signalling from the calcium-sensing receptor for the pharmacotherapy of diverse disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5813271

3 July 2018

Mutations affecting G-protein subunit α11 in hypercalcemia and hypocalcemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5813271

3 July 2018

Structural and Functional Analysis of the Regulator of G Protein Signaling 2-Gαq Complex

1 reference

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3 July 2018

Predicting functional effect of human missense mutations using PolyPhen-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5813271

3 July 2018

Mutations in AP2S1 cause familial hypocalciuric hypercalcemia type 3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5813271

3 July 2018

Signaling through the extracellular calcium-sensing receptor (CaSR).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5813271

3 July 2018

Mutations in GNA11 in uveal melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5813271

3 July 2018

Kinetic Scaffolding Mediated by a Phospholipase C- and Gq Signaling Complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5813271

3 July 2018

Structural basis for the specific inhibition of heterotrimeric Gq protein by a small molecule

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5813271

3 July 2018

Heterotrimeric G protein activation by G-protein-coupled receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5813271

3 July 2018

Identification of an alternative G{alpha}q-dependent chemokine receptor signal transduction pathway in dendritic cells and granulocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5813271

3 July 2018

Receptor-mediated activation of heterotrimeric G-proteins: current structural insights.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5813271

3 July 2018

Mammalian G proteins and their cell type specific functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5813271

3 July 2018

Calcium-sensing receptor-mediated ERK1/2 activation requires Galphai2 coupling and dynamin-independent receptor internalization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5813271

3 July 2018

Extracellular calcium sensing and signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5813271

3 July 2018

Regulation of MAP kinase by calcium-sensing receptor in bovine parathyroid and CaR-transfected HEK293 cells

1 reference

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3 July 2018

Amino acids in the second and third intracellular loops of the parathyroid Ca2+-sensing receptor mediate efficient coupling to phospholipase C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5813271

3 July 2018

Protein kinase C phosphorylation of threonine at position 888 in Ca2+o-sensing receptor (CaR) inhibits coupling to Ca2+ store release

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5813271

3 July 2018

The Ca2+-sensing receptor (CaR) activates phospholipases C, A2, and D in bovine parathyroid and CaR-transfected, human embryonic kidney (HEK293) cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5813271

3 July 2018

The structure of the G protein heterotrimer Gi alpha 1 beta 1 gamma 2

1 reference

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3 July 2018

High extracellular Ca2+ and Mg2+ stimulate accumulation of inositol phosphates in bovine parathyroid cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5813271

3 July 2018

Activation of phospholipase C by the alpha subunits of the Gq and G11 proteins in transfected Cos-7 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5813271

3 July 2018

MutationTaster2: mutation prediction for the deep-sequencing age.

1 reference

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14 August 2018

Calcium-sensing receptor (CaSR) mutations and disorders of calcium, electrolyte and water metabolism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5813271

14 August 2018

Snapshot of activated G proteins at the membrane: the Galphaq-GRK2-Gbetagamma complex.

1 reference

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14 August 2018

Cinacalcet for secondary hyperparathyroidism in patients receiving hemodialysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5813271

14 August 2018

High calcium and other divalent cations increase inositol trisphosphate in bovine parathyroid cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/28833550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correction of hypercalcaemia by cinacalcet in familial hypocalciuric hypercalcaemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/28833550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cinacalcet Treatment in an Adolescent With Concurrent 22q11.2 Deletion Syndrome and Familial Hypocalciuric Hypercalcemia Type 3 Caused by AP2S1 Mutation

1 reference

https://pubmed.ncbi.nlm.nih.gov/28833550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/JBMR.3241

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28833550%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28833550%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28833550%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

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