(Q47917104)

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Cannabidiol normalizes caspase 3, synaptophysin, and mitochondrial fission protein DNM1L expression levels in rats with brain iron overload: implications for neuroprotection.

scientific article published on 28 July 2013

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6 March 2020

Cannabidiol normalizes caspase 3, synaptophysin, and mitochondrial fission protein DNM1L expression levels in rats with brain iron overload: implications for neuroprotection (English)

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6 March 2020

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6 March 2020

José Alexandre de Souza Crippa

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José Alexandre S Crippa

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6 March 2020

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Vanessa Kappel da Silva

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6 March 2020

Betânia Souza de Freitas

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6 March 2020

Arethuza da Silva Dornelles

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6 March 2020

Laura Roesler Nery

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6 March 2020

Lucio Falavigna

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6 March 2020

Rafael Dal Ponte Ferreira

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6 March 2020

Maurício Reis Bogo

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6 March 2020

Jaime Eduardo Cecílio Hallak

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6 March 2020

Antônio Waldo Zuardi

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6 March 2020

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28 July 2013

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6 March 2020

Molecular Neurobiology

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6 March 2020

49

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6 March 2020

1

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6 March 2020

222-233

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6 March 2020

https://scigraph.springernature.com/pub.10.1007/s12035-013-8514-7

0 references

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1 reference

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Alterations in the levels of iron, ferritin and other trace metals in Parkinson's disease and other neurodegenerative diseases affecting the basal ganglia

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Selective accumulation of aluminum and iron in the neurofibrillary tangles of Alzheimer's disease: a laser microprobe (LAMMA) study

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21 January 2018

Iron, brain ageing and neurodegenerative disorders

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21 January 2018

High-field magnetic resonance imaging of brain iron in Alzheimer disease

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Individual dopaminergic neurons show raised iron levels in Parkinson disease.

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Quantitative MR phase-corrected imaging to investigate increased brain iron deposition of patients with Alzheimer disease.

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21 January 2018

Biological significance of iron-related magnetic resonance imaging changes in the brain

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21 January 2018

Relevance of Iron Deposition in Deep Gray Matter Brain Structures to Cognitive and Motor Performance in Healthy Elderly Men and Women: Exploratory Findings

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21 January 2018

Gender and iron genes may modify associations between brain iron and memory in healthy aging

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21 January 2018

Brain iron deposits are associated with general cognitive ability and cognitive aging.

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21 January 2018

The role of hippocampal iron concentration and hippocampal volume in age-related differences in memory

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21 January 2018

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21 January 2018

Correlation of iron in the hippocampus with MMSE in patients with Alzheimer's disease

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21 January 2018

Neonatal iron exposure induces neurobehavioural dysfunctions in adult mice.

1 reference

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21 January 2018

Memory deficits in adult rats following postnatal iron administration

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21 January 2018

Recognition memory impairment and brain oxidative stress induced by postnatal iron administration

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21 January 2018

Dynamic changes of mitochondrial fusion and fission proteins after transient cerebral ischemia in mice.

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21 January 2018

The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease

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21 January 2018

Mitochondrial fission in apoptosis, neurodegeneration and aging

1 reference

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21 January 2018

Synaptic energy use and supply

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Age-related loss of synapses in the frontal cortex of SAMP10 mouse: a model of cerebral degeneration

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21 January 2018

Cannabidiol and (-)Delta9-tetrahydrocannabinol are neuroprotective antioxidants

1 reference

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Evaluation of the neuroprotective effect of cannabinoids in a rat model of Parkinson's disease: importance of antioxidant and cannabinoid receptor-independent properties.

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21 January 2018

The neuroprotective effect of cannabidiol in an in vitro model of newborn hypoxic-ischemic brain damage in mice is mediated by CB(2) and adenosine receptors.

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Neuroprotective effect of cannabidiol, a non-psychoactive component from Cannabis sativa, on beta-amyloid-induced toxicity in PC12 cells

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21 January 2018

Cannabidiol administration after hypoxia-ischemia to newborn rats reduces long-term brain injury and restores neurobehavioral function.

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21 January 2018

Cannabidiol reduced the striatal atrophy caused 3-nitropropionic acid in vivo by mechanisms independent of the activation of cannabinoid, vanilloid TRPV1 and adenosine A2A receptors.

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21 January 2018

Memory-rescuing effects of cannabidiol in an animal model of cognitive impairment relevant to neurodegenerative disorders.

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21 January 2018

The therapeutic potential of the endocannabinoid system for Alzheimer's disease

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21 January 2018

Memory impairment induced by brain iron overload is accompanied by reduced H3K9 acetylation and ameliorated by sodium butyrate.

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21 January 2018

Inactivation of cytochrome c oxidase by mutant SOD1s in mouse motoneuronal NSC-34 cells is independent from copper availability but is because of nitric oxide.

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Reduction of Na+, K+-ATPase activity and expression in cerebral cortex of glutaryl-CoA dehydrogenase deficient mice: a possible mechanism for brain injury in glutaric aciduria type I.

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Mitochondrial remodeling following fission inhibition by 15d-PGJ2 involves molecular changes in mitochondrial fusion protein OPA1.

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Caspases indirectly regulate cleavage of the mitochondrial fusion GTPase OPA1 in neurons undergoing apoptosis

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Differential effect of intrauterine hypoxia on caspase 3 and DNA fragmentation in fetal guinea pig hearts and brains

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Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage

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Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins

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Neonatal iron exposure induces oxidative stress in adult Wistar rat.

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Neonatal iron treatment increases apoptotic markers in hippocampal and cortical areas of adult rats.

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1 reference

https://pubmed.ncbi.nlm.nih.gov/23893294

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential loss of synaptic proteins in Alzheimer's disease: implications for synaptic dysfunction.

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diminished gray matter in the hippocampus of cannabis users: possible protective effects of cannabidiol

1 reference

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Quantitative MR imaging R2 relaxometry in elderly participants reporting memory loss

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

Mitochondrial iron metabolism and its role in neurodegeneration.

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis in the central nervous system: Mechanisms and protective strategies

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of the presynaptic vesicle protein synaptophysin in hippocampus correlates with cognitive decline in Alzheimer disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23893294

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S12035-013-8514-7

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6 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23893294%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

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