(Q47929711)

English

Decreased Binding of Peptides-MHC Class I (pMHC) Multimeric Complexes to CD8 Affects Their Binding Avidity for the TCR But Does Not Significantly Impact on pMHC/TCR Dissociation Rate

scientific article published on May 15, 2003

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scholarly article

1 reference

Europe PubMed Central

6 February 2018

http://europepmc.org/abstract/MED/12734357

Decreased Binding of Peptides-MHC Class I (pMHC) Multimeric Complexes to CD8 Affects Their Binding Avidity for the TCR But Does Not Significantly Impact on pMHC/TCR Dissociation Rate (English)

1 reference

10.4049/JIMMUNOL.170.10.5110

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5110

31 December 2023

1 reference

10.4049/JIMMUNOL.170.10.5110

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5110

31 December 2023

6

object named as

Danila Valmori

1 reference

Europe PubMed Central

6 February 2018

http://europepmc.org/abstract/MED/12734357

3

object named as

Maha Ayyoub

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12734357

31 December 2023

author name string

Valérie Dutoit

1

1 reference

Europe PubMed Central

6 February 2018

http://europepmc.org/abstract/MED/12734357

Philippe Guillaume

2

1 reference

Europe PubMed Central

6 February 2018

http://europepmc.org/abstract/MED/12734357

Charles S. Hesdorffer

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12734357

31 December 2023

Immanuel F. Luescher

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12734357

31 December 2023

language of work or name

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publication date

1 May 2003

1 reference

Europe PubMed Central

6 February 2018

http://europepmc.org/abstract/MED/12734357

15 May 2003

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12734357

31 December 2023

full work available at URL

Journal of Immunology

1 reference

Europe PubMed Central

6 February 2018

http://europepmc.org/abstract/MED/12734357

170

1 reference

Europe PubMed Central

6 February 2018

http://europepmc.org/abstract/MED/12734357

10

1 reference

Europe PubMed Central

6 February 2018

http://europepmc.org/abstract/MED/12734357

5110-5117

1 reference

Europe PubMed Central

6 February 2018

http://europepmc.org/abstract/MED/12734357

Molecular components of T-cell recognition

1

1 reference

10.4049/JIMMUNOL.170.10.5110

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5110

31 December 2023

Structural basis of T cell recognition

2

1 reference

10.4049/JIMMUNOL.170.10.5110

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5110

31 December 2023

The T cell receptor as a multicomponent signalling machine: CD4/CD8 coreceptors and CD45 in T cell activation

3

1 reference

10.4049/JIMMUNOL.170.10.5110

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5110

31 December 2023

Replacement of pre-T cell receptor signaling functions by the CD4 coreceptor

4

1 reference

10.4049/JIMMUNOL.170.10.5110

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5110

31 December 2023

CD8: from coreceptor to comodulator

5

1 reference

10.4049/JIMMUNOL.170.10.5110

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5110

31 December 2023

Molecular coordination of alphabeta T-cell receptors and coreceptors CD8 and CD4 in their recognition of peptide-MHC ligands

6

1 reference

10.4049/JIMMUNOL.170.10.5110

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5110

31 December 2023

An alphabeta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex

7

1 reference

10.4049/JIMMUNOL.170.10.5110

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5110

31 December 2023

Molecular mechanism of T-cell activation: role of protein tyrosine kinases in antigen receptor-mediated signal transduction.

8

1 reference

10.4049/JIMMUNOL.170.10.5110

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5110

31 December 2023

Classical and nonclassical class I major histocompatibility complex molecules exhibit subtle conformational differences that affect binding to CD8alphaalpha

9

1 reference

10.4049/JIMMUNOL.170.10.5110

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5110

31 December 2023

The human CD8 coreceptor effects cytotoxic T cell activation and antigen sensitivity primarily by mediating complete phosphorylation of the T cell receptor zeta chain.

10

1 reference

10.4049/JIMMUNOL.170.10.5110

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5110

31 December 2023

A binding site for the T-cell co-receptor CD8 on the alpha 3 domain of HLA-A2.

11

1 reference

10.4049/JIMMUNOL.170.10.5110

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5110

31 December 2023

Phenotypic analysis of antigen-specific T lymphocytes

16

1 reference

10.4049/JIMMUNOL.170.10.5110

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5110

31 December 2023

Impact of Antigen Presentation on TCR Modulation and Cytokine Release: Implications for Detection and Sorting of Antigen-Specific CD8+ T Cells Using HLA-A2 Wild-Type or HLA-A2 Mutant Tetrameric Complexes

17

1 reference

10.4049/JIMMUNOL.170.10.5110

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5110

31 December 2023

Reverse ELISPOT assay for clonal analysis of cytokine production I. Enumeration of gamma-interferon-secreting cells

18

1 reference

10.4049/JIMMUNOL.170.10.5110

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5110

31 December 2023

Crystal structure of the complex between human CD8alpha(alpha) and HLA-A2

19

1 reference

10.4049/JIMMUNOL.170.10.5110

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5110

31 December 2023

Polymorphism in the alpha 3 domain of HLA-A molecules affects binding to CD8.

20

1 reference

10.4049/JIMMUNOL.170.10.5110

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5110

31 December 2023

Functional avidity of tumor antigen-specific CTL recognition directly correlates with the stability of MHC/peptide multimer binding to TCR

21

1 reference

10.4049/JIMMUNOL.170.10.5110

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5110

31 December 2023

Dissecting TCR-MHC/peptide complex interactions with A2/peptide multimers incorporating tumor antigen peptide variants: crucial role of interaction kinetics on functional outcomes

22

1 reference

10.4049/JIMMUNOL.170.10.5110

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5110

31 December 2023

Discrepancy between ELISPOT IFN-gamma secretion and binding of A2/peptide multimers to TCR reveals interclonal dissociation of CTL effector function from TCR-peptide/MHC complexes half-life

23

1 reference

10.4049/JIMMUNOL.170.10.5110

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5110

31 December 2023

Critical role for CD8 in binding of MHC tetramers to TCR: CD8 antibodies block specific binding of human tumor-specific MHC-peptide tetramers to TCR.

24

1 reference

10.4049/JIMMUNOL.170.10.5110

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5110

31 December 2023

Critical role for CD8 in T cell receptor binding and activation by peptide/major histocompatibility complex multimers

25

1 reference

10.4049/JIMMUNOL.170.10.5110

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5110

31 December 2023

Kinetic proofreading in T-cell receptor signal transduction

26

1 reference

10.4049/JIMMUNOL.170.10.5110

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5110

31 December 2023

A TCR binds to antagonist ligands with lower affinities and faster dissociation rates than to agonists

27

1 reference

10.4049/JIMMUNOL.170.10.5110

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5110

31 December 2023

Kinetic discrimination in T-cell activation

28

1 reference

10.4049/JIMMUNOL.170.10.5110

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5110

31 December 2023

Low Affinity Interaction of Peptide-MHC Complexes with T Cell Receptors

29

1 reference

10.4049/JIMMUNOL.170.10.5110

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5110

31 December 2023

Specific low-affinity recognition of major histocompatibility complex plus peptide by soluble T-cell receptor

30

1 reference

10.4049/JIMMUNOL.170.10.5110

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5110

31 December 2023

Kinetics and affinity of reactions between an antigen-specific T cell receptor and peptide-MHC complexes

31

1 reference

10.4049/JIMMUNOL.170.10.5110

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5110

31 December 2023

T cell receptor-MHC class I peptide interactions: affinity, kinetics, and specificity

32

1 reference

10.4049/JIMMUNOL.170.10.5110

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5110

31 December 2023

Kinetics of T-cell receptor binding to peptide/I-Ek complexes: correlation of the dissociation rate with T-cell responsiveness

33

1 reference

10.4049/JIMMUNOL.170.10.5110

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5110

31 December 2023

T cell receptor and coreceptor CD8 alphaalpha bind peptide-MHC independently and with distinct kinetics

34

1 reference

10.4049/JIMMUNOL.170.10.5110

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5110

31 December 2023

CD8 enhances formation of stable T-cell receptor/MHC class I molecule complexes

35

1 reference

10.4049/JIMMUNOL.170.10.5110

https://api.crossref.org/works/10.4049/JIMMUNOL.170.10.5110

31 December 2023

Identifiers

10.4049/JIMMUNOL.170.10.5110

1 reference

Europe PubMed Central

6 February 2018

http://europepmc.org/abstract/MED/12734357

1 reference

Europe PubMed Central

6 February 2018

http://europepmc.org/abstract/MED/12734357

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