(Q47935016)

6 February 2018

title

Systematic Identification of MCU Modulators by Orthogonal Interspecies Chemical Screening (English)

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6 February 2018

author

Guillaume Médard

11

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6 February 2018

Dejana Mokranjac

object named as

Dejana Mokranjac

14

0 references

Fabiana Perocchi

17

object named as

Fabiana Perocchi

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6 February 2018

author name string

Daniela M Arduino

1

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6 February 2018

Jennifer Wettmarshausen

2

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6 February 2018

Horia Vais

3

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6 February 2018

Paloma Navas-Navarro

4

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6 February 2018

Yiming Cheng

5

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6 February 2018

Anja Leimpek

6

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6 February 2018

Zhongming Ma

7

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6 February 2018

Alba Delrio-Lorenzo

8

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6 February 2018

Andrea Giordano

9

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6 February 2018

Cecilia Garcia-Perez

10

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6 February 2018

Bernhard Kuster

12

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6 February 2018

Javier García-Sancho

13

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6 February 2018

J Kevin Foskett

15

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6 February 2018

M Teresa Alonso

16

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6 February 2018

publication date

1 August 2017

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6 February 2018

published in

Molecular Cell

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6 February 2018

volume

67

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6 February 2018

issue

4

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6 February 2018

page(s)

711-723.e7

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6 February 2018

Ion and inhibitor binding of the double-ring ion selectivity filter of the mitochondrial calcium uniporter

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Synthetic Methods for the Preparation of a Functional Analogue of Ru360, a Potent Inhibitor of Mitochondrial Calcium Uptake

26 August 2018

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Structural Insights into Mitochondrial Calcium Uniporter Regulation by Divalent Cations

26 August 2018

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Enjoy the Trip: Calcium in Mitochondria Back and Forth

26 August 2018

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26 August 2018

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Molecular structure and pathophysiological roles of the Mitochondrial Calcium Uniporter

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EMRE Is a Matrix Ca(2+) Sensor that Governs Gatekeeping of the Mitochondrial Ca(2+) Uniporter.

26 August 2018

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26 August 2018

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Structure and function of the N-terminal domain of the human mitochondrial calcium uniporter

26 August 2018

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26 August 2018

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Antimicrobial agent triclosan is a proton ionophore uncoupler of mitochondria in living rat and human mast cells and in primary human keratinocytes

26 August 2018

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The mitochondrial Ca(2+) uniporter complex

26 August 2018

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Analysis and interpretation of microplate-based oxygen consumption and pH data

26 August 2018

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Profiling of the Tox21 chemical collection for mitochondrial function to identify compounds that acutely decrease mitochondrial membrane potential

26 August 2018

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Reconstitution of the mitochondrial calcium uniporter in yeast

26 August 2018

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The mitochondrial calcium uniporter complex: molecular components, structure and physiopathological implications

26 August 2018

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26 August 2018

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MCU encodes the pore conducting mitochondrial calcium currents

26 August 2018

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Activity of the mitochondrial calcium uniporter varies greatly between tissues

26 August 2018

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Role of the AAA protease Yme1 in folding of proteins in the intermembrane space of mitochondria

26 August 2018

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Mitochondrial calcium homeostasis as potential target for mitochondrial medicine

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5825229

Assessing mitochondrial dysfunction in cells.

26 August 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5825229

A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter

26 August 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5825229

Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter

26 August 2018

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MICU1 encodes a mitochondrial EF hand protein required for Ca(2+) uptake

26 August 2018

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26 August 2018

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NCLX is an essential component of mitochondrial Na+/Ca2+ exchange

26 August 2018

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Red and green aequorins for simultaneous monitoring of Ca2+ signals from two different organelles.

26 August 2018

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Nuclear calcium signaling by inositol trisphosphate in GH3 pituitary cells

26 August 2018

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Adaphostin and other anticancer drugs quench the fluorescence of mitochondrial potential probes

26 August 2018

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Clinically approved heterocyclics act on a mitochondrial target and reduce stroke-induced pathology.

26 August 2018

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The mitochondrial calcium uniporter is a highly selective ion channel.

26 August 2018

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Calcium uptake by rat kidney mitochondria

26 August 2018

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Designing screens: how to make your hits a hit.

26 August 2018

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Concentration dependent mitochondrial effect of amiodarone

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5825229

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

26 August 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5825229

Intracellular concentrations of mitoxantrone in leukemic cells in vitro vs in vivo.

26 August 2018

1 reference

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Transport of calcium by mitochondria

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5825229

Yeast vectors for the controlled expression of heterologous proteins in different genetic backgrounds

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5825229

A survey of the interaction of calcium ions with mitochondria from different tissues and species

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5825229

The effect of hexachlorophene on the respiration of brain and liver mitochondria.

26 August 2018

1 reference

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A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5825229

Inhibition of mitochondrial calcium ion transport by an oxo-bridged dinuclear ruthenium ammine complex

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5825229

Effect of trifluoperazine on skeletal muscle mitochondrial respiration

26 August 2018

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12 December 2020

Characterization of the fluorescence of the antitumor agent, mitoxantrone

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12 December 2020

Specific inhibition of mitochondrial Ca++ transport by ruthenium red

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12 December 2020

Utilization by yeast of D-lactate and L-lactate as sources of energy in the presence of antimycin A

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12 December 2020

Outstanding questions regarding the permeation, selectivity, and regulation of the mitochondrial calcium uniporter

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12 December 2020

Chromaffin-cell stimulation triggers fast millimolar mitochondrial Ca2+ transients that modulate secretion

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12 December 2020

Effects of tamoxifen on the electron transport chain of isolated rat liver mitochondria

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12 December 2020

The effects of miconazole on rat liver mitochondria

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Antineoplastic agents. Structure-activity relationship study of bis(substituted aminoalkylamino)anthraquinones

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Effects of Carvedilol on Isolated Heart Mitochondria: Evidence for a Protonophoretic Mechanism

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12 December 2020

Ca ion uptake by rat kidney mitochondria and its dependence on respiration and phosphorylation

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12 December 2020

10.1016/J.MOLCEL.2017.07.019

Identifiers

DOI

1 reference

6 February 2018

PMC publication ID

5825229

0 references

1 reference

6 February 2018