(Q47956436)

21 February 2018

title

Prostate cancer-associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4. (English)

1 reference

21 February 2018

author

Qing Zhong

8

1 reference

7 February 2018

Francisco Beca

13

1 reference

7 February 2018

Mark Rubin

25

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7 February 2018

Christopher E. Barbieri

26

1 reference

7 February 2018

Levi A Garraway

24

object named as

Levi A Garraway

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21 February 2018

author name string

Xiangpeng Dai

1

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21 February 2018

Wenjian Gan

2

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21 February 2018

Xiaoning Li

3

1 reference

21 February 2018

Shangqian Wang

4

1 reference

21 February 2018

Wei Zhang

5

1 reference

21 February 2018

Ling Huang

6

1 reference

21 February 2018

Shengwu Liu

7

1 reference

21 February 2018

Jianping Guo

9

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21 February 2018

Jinfang Zhang

10

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21 February 2018

Ting Chen

11

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21 February 2018

Kouhei Shimizu

12

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21 February 2018

Mirjam Blattner

14

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21 February 2018

Divya Vasudevan

15

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21 February 2018

Dennis L Buckley

16

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21 February 2018

Jun Qi

17

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21 February 2018

Lorenz Buser

18

1 reference

21 February 2018

Pengda Liu

19

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21 February 2018

Hiroyuki Inuzuka

20

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21 February 2018

Andrew H Beck

21

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21 February 2018

Liewei Wang

22

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21 February 2018

Peter J Wild

23

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21 February 2018

Kwok-Kin Wong

27

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21 February 2018

Senthil K Muthuswamy

28

1 reference

21 February 2018

Jiaoti Huang

29

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21 February 2018

Yu Chen

30

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21 February 2018

James E Bradner

31

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21 February 2018

Wenyi Wei

32

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21 February 2018

language of work or name

English

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publication date

14 August 2017

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21 February 2018

published in

Nature Medicine

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21 February 2018

volume

23

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21 February 2018

issue

9

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21 February 2018

page(s)

1063-1071

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21 February 2018

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5625299/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/nm.4378

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cites work

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Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer

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Transcriptional plasticity promotes primary and acquired resistance to BET inhibition

22 May 2018

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Prostate cancer. Ubiquitylome analysis identifies dysregulation of effector substrates in SPOP-mutant prostate cancer

22 May 2018

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22 May 2018

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22 May 2018

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22 May 2018

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22 May 2018

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22 May 2018

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The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins

22 May 2018

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22 May 2018

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22 May 2018

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Phospho switch triggers Brd4 chromatin binding and activator recruitment for gene-specific targeting

22 May 2018

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BET domain co-regulators in obesity, inflammation and cancer

22 May 2018

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22 May 2018

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Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer

22 May 2018

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22 May 2018

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BET bromodomain inhibition as a therapeutic strategy to target c-Myc

22 May 2018

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Common gene rearrangements in prostate cancer

22 May 2018

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COP1 is a tumour suppressor that causes degradation of ETS transcription factors

22 May 2018

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22 May 2018

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Selective inhibition of BET bromodomains

22 May 2018

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Phosphorylation by casein kinase I promotes the turnover of the Mdm2 oncoprotein via the SCF(beta-TRCP) ubiquitin ligase

22 May 2018

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Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases

22 May 2018

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Recurrent gene fusions in prostate cancer

22 May 2018

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Bromodomain 4 activation predicts breast cancer survival

22 May 2018

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The double bromodomain-containing chromatin adaptor Brd4 and transcriptional regulation

22 May 2018

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22 May 2018

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22 May 2018

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22 May 2018

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Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex

22 May 2018

1 reference

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BRD4-NUT fusion oncogene: a novel mechanism in aggressive carcinoma

22 May 2018

1 reference

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Bromodomain: an acetyl-lysine binding domain

22 May 2018

1 reference

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Mechanisms of cancer drug resistance

22 May 2018

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The 2016 WHO Classification of Tumours of the Urinary System and Male Genital Organs-Part B: Prostate and Bladder Tumours.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5625299

14 August 2018

Identifiers

DOI

10.1038/NM.4378

1 reference

21 February 2018

PMCID

5625299

1 reference

21 February 2018

PubMed ID

28805820

1 reference

21 February 2018