(Q38835493)

6 September 2017

title

BET inhibitor resistance emerges from leukaemia stem cells (English)

1 reference

6 September 2017

1 reference

Paul Yeh

9

0 references

Sarah-Jane Dawson

Sarah-Jane Dawson

22

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Mark A. Dawson

Mark A Dawson

26

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Ricky W Johnstone

Ricky W Johnstone

21

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Anthony T. Papenfuss

Anthony T Papenfuss

25

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Robert G. Ramsay

Robert G Ramsay

17

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Tony Kouzarides

Tony Kouzarides

20

0 references

Chun Yew Fong

Chun Yew Fong

1

0 references

George Giotopoulos

George Giotopoulos

11

0 references

Stanley C Lee

Stanley Chun-Wei Lee

14

0 references

Alan F Rubin

Alan F Rubin

4

0 references

author name string

Omer Gilan

2

1 reference

6 September 2017

Enid Y N Lam

3

1 reference

6 September 2017

Sarah Ftouni

5

1 reference

6 September 2017

Dean Tyler

6

1 reference

6 September 2017

Kym Stanley

7

1 reference

6 September 2017

Devbarna Sinha

8

1 reference

6 September 2017

Jessica Morison

10

1 reference

6 September 2017

Dave Lugo

12

1 reference

6 September 2017

Philip Jeffrey

13

1 reference

6 September 2017

Christopher Carpenter

15

1 reference

6 September 2017

Richard Gregory

16

1 reference

6 September 2017

Steven W Lane

18

1 reference

6 September 2017

Omar Abdel-Wahab

19

1 reference

6 September 2017

Brian J P Huntly

23

1 reference

6 September 2017

Rab K Prinjha

24

1 reference

6 September 2017

language of work or name

English

0 references

publication date

14 September 2015

1 reference

6 September 2017

1 reference

6 September 2017

volume

525

1 reference

6 September 2017

issue

7570

1 reference

6 September 2017

page(s)

538-542

1 reference

describes a project that uses

6 September 2017

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/6069604

based on heuristic

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/nature14888

0 references

cites work

Transcriptional plasticity promotes primary and acquired resistance to BET inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6069604

The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6069604

The mechanisms behind the therapeutic activity of BET bromodomain inhibition

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6069604

An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6069604

A New Bliss Independence Model to Analyze Drug Combination Data

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6069604

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6069604

Recurrent mutations, including NPM1c, activate a BRD4-dependent core transcriptional program in acute myeloid leukemia

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6069604

Chromatin proteins and modifications as drug targets

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6069604

Cancer drug resistance: an evolving paradigm

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6069604

Selective inhibition of tumor oncogenes by disruption of super-enhancers

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6069604

The Subread aligner: fast, accurate and scalable read mapping by seed-and-vote

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6069604

Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6069604

CoNVEX: copy number variation estimation in exome sequencing data using HMM

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6069604

Cell of origin determines clinically relevant subtypes of MLL-rearranged AML

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6069604

Cancer stem cell definitions and terminology: the devil is in the details.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6069604

Targeting epigenetic readers in cancer.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6069604

Cancer epigenetics: from mechanism to therapy

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6069604

VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencing

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6069604

GenomicTools: a computational platform for developing high-throughput analytics in genomics.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6069604

Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6069604

Stem cell gene expression programs influence clinical outcome in human leukemia.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6069604

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6069604

β-Catenin mediates the establishment and drug resistance of MLL leukemic stem cells

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6069604

Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6069604

Selective inhibition of BET bromodomains

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6069604

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6069604

ROAST: rotation gene set tests for complex microarray experiments

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6069604

Deriving the consequences of genomic variants with the Ensembl API and SNP Effect Predictor

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6069604

The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6069604

ELDA: extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6069604

Fast and accurate short read alignment with Burrows-Wheeler transform

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6069604

Model-based analysis of ChIP-Seq (MACS)

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6069604

Second generation inhibitors of BCR-ABL for the treatment of imatinib-resistant chronic myeloid leukaemia

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6069604

Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6069604

Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6069604

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6069604

Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6069604

The UCSC Table Browser data retrieval tool

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6069604

Coexistence of LMPP-like and GMP-like Leukemia Stem Cells in Acute Myeloid Leukemia

31 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26367796

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE14888

1 reference

6 September 2017

0 references

1 reference