(Q47962165)

7 February 2018

review article

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title

Evolution of the cytochrome P450 superfamily: sequence alignments and pharmacogenetics (English)

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7 February 2018

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D F Lewis

1

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7 February 2018

E Watson

series ordinal

2

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7 February 2018

B G Lake

series ordinal

3

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7 February 2018

language of work or name

English

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publication date

1 June 1998

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7 February 2018

published in

Mutation Research

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7 February 2018

volume

410

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7 February 2018

issue

3

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7 February 2018

page(s)

245-270

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7 February 2018

The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature

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7 January 2021

P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature.

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7 January 2021

The P450 superfamily: updated listing of all genes and recommended nomenclature for the chromosomal loci

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7 January 2021

Evolution of the cytochrome P450 genes

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7 January 2021

P450 genes: structure, evolution, and regulation

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7 January 2021

Evolution of the P450 gene superfamily: animal-plant 'warfare', molecular drive and human genetic differences in drug oxidation

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7 January 2021

Multiple forms of cytochrome P-450 and the importance of molecular biology and evolution

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7 January 2021

Evidence for life on Earth before 3,800 million years ago

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7 January 2021

P450 gene nomenclature based on evolution.

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7 January 2021

Evolution of the P450 gene superfamily and regulation of the murine Cyp1a1 gene

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7 January 2021

Molecular evolution of P450 superfamily and P450-containing monooxygenase systems

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7 January 2021

Crystal structure of hemoprotein domain of P450BM-3, a prototype for microsomal P450's

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7 January 2021

Three-dimensional models of human and other mammalian microsomal P450s constructed from an alignment with P450102 (P450bm3)

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7 January 2021

High-resolution crystal structure of cytochrome P450cam

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7 January 2021

Crystal structure and refinement of cytochrome P450terp at 2.3 A resolution

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7 January 2021

Structure of cytochrome P450eryF involved in erythromycin biosynthesis

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7 January 2021

Late Proterozoic rise in atmospheric oxygen concentration inferred from phylogenetic and sulphur-isotope studies

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https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

Breathing room for early animals

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7 January 2021

The early evolution of eukaryotes: a geological perspective

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7 January 2021

Mitochondrial origins

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7 January 2021

Formation of amide bonds without a condensation agent and implications for origin of life

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7 January 2021

On the nature of global classification

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7 January 2021

Early role during chemical evolution for cytochrome P450 in oxygen detoxification

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https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

On the Origin and Rise of Oxygen Concentration in the Earth's Atmosphere

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https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

Beginnings of biospheric evolution and their biogeochemical consequences

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https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

Continental breakup and the ordinal diversification of birds and mammals

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https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

Tidal imprint of distant galactic matter on the Oort comet cloud

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https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

Determining divergence times of the major kingdoms of living organisms with a protein clock

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https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

Structural flexibility and functional versatility of cytochrome P450 and rapid evolution

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https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

A cluster of cytochrome P450 genes of the CYP6 family in the house fly.

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https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

Body size, metabolic rate, generation time, and the molecular clock

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https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster.

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https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

Organization and evolution of the cytochrome P450 CYP2A-2B-2F subfamily gene cluster on human chromosome 19

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https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

Molecular modelling of members of the P4502A subfamily: application to studies of enzyme specificity

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https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

Pharmacogenetic phenotyping and genotyping. Present status and future potential.

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https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

Human drug-metabolizing enzyme polymorphisms: effects on risk of toxicity and cancer

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https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

Nomenclature for human CYP2D6 alleles.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

1 reference

7 January 2021

Pharmacogenetics in clinical pharmacology and toxicology.

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https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

Genetic tests which identify the principal defects in CYP2C19 responsible for the polymorphism in mephenytoin metabolism

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https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

Identification of allelic variants of the human CYP1A1 gene

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

Molecular modelling of CYP1A subfamily members based on an alignment with CYP102: rationalization of CYP1A substrate specificity in terms of active site amino acid residues

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https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

Relationship between CYP2C9 and 2C19 genotypes and tolbutamide methyl hydroxylation and S-mephenytoin 4'-hydroxylation activities in livers of Japanese and Caucasian populations

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https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

Genetic polymorphism of human cytochrome P450 2E1

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https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

Species variation in the response of the cytochrome P-450-dependent monooxygenase system to inducers and inhibitors.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

Molecular modelling of CYP2E1 enzymes from rat, mouse and man: an explanation for species differences in butadiene metabolism and potential carcinogenicity, and rationalization of CYP2E substrate specificity

1 reference

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7 January 2021

The metabolism of tamoxifen by human cytochromes P450 is rationalized by molecular modelling of the enzyme-substrate interactions: potential importance to its proposed anti-carcinogenic/carcinogenic actions

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

The Substrate Binding Site of Human Liver Cytochrome P450 2C9: An Approach Using Designed Tienilic Acid Derivatives and Molecular Modeling

1 reference

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7 January 2021

Application of 3-Dimensional Homology Modeling of Cytochrome P450 2B1 for Interpretation of Site-Directed Mutagenesis Results

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https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

A preliminary 3D model for cytochrome P450 2D6 constructed by homology model building

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

Modeling cytochrome P450 14 alpha demethylase (Candida albicans) from P450cam.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

Structure and function of cytochromes P450: a comparative analysis of three crystal structures.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

P450s: structural similarities and functional differences.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

Secondary structure prediction of 52 membrane-bound cytochromes P450 shows a strong structural similarity to P450cam

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

Structural alignments of P450s and extrapolations to the unknown

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

Identification and location of alpha-helices in mammalian cytochromes P450

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

Proteins from eight eukaryotic cytochrome P-450 families share a segmented region of sequence similarity

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

Primary and secondary structural patterns in eukaryotic cytochrome P-450 families correspond to structures of the helix-rich domain of Pseudomonas putida cytochrome P-450cam. Indications for a similar overall topology

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

Secondary structure and membrane topology of cytochrome P450s.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

Comparison of the construction of a 3-D model for human thromboxane synthase using P450cam and BM-3 as templates: implications for the substrate binding pocket

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

Influence of amino acid residue 374 of cytochrome P-450 2D6 (CYP2D6) on the regio- and enantio-selective metabolism of metoprolol

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

Molecular modelling of mammalian CYP2B isoforms and their interaction with substrates, inhibitors and redox partners

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

Molecular modelling of steroidogenic cytochromes P450 from families CYP11, CYP17, CYP19 and CYP21 based on the CYP102 crystal structure

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

Molecular orbital-generated QSARs in a homologous series of alkoxyresorufins and studies of their interactive docking with P450s

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

Site-Directed Mutagenesis as a Tool for Molecular Modeling of Cytochrome P450 2B1

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

Molecular modelling of CYP3A4 from an alignment with CYP102: identification of key interactions between putative active site residues and CYP3A-specific chemicals

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

Molecular modelling of cytochrome P4502D6 (CYP2D6) based on an alignment with CYP102: structural studies on specific CYP2D6 substrate metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

Molecular modelling of human CYP2C subfamily enzymes CYP2C9 and CYP2C19: rationalization of substrate specificity and site-directed mutagenesis experiments in the CYP2C subfamily

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

The relation between the divergence of sequence and structure in proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

Functional evolutionary divergence of proteolytic enzymes and their inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2897%2900040-9

7 January 2021

https://opencitations.net/index/coci/api/v1/citations/10.1128/MR.51.2.221-271.1987

1 reference

18 October 2022

Identifiers

DOI

10.1016/S1383-5742(97)00040-9

1 reference

7 February 2018

1 reference

7 February 2018