(Q48034526)

http://europepmc.org/abstract/MED/28975867

7 February 2018

title

The pharmacogenomics of severe traumatic brain injury. (English)

1 reference

http://europepmc.org/abstract/MED/28975867

7 February 2018

1 reference

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28975867%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Philip E Empey

8

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28975867%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

3

Amy K Wagner

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28975867%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

2

Yvette P Conley

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28975867%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

author name string

Ruchira M Jha

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28975867%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Robert Sb Clark

5

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28975867%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Samuel M Poloyac

6

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28975867%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Patrick M Kochanek

7

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28975867%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

publication date

4 October 2017

1 reference

http://europepmc.org/abstract/MED/28975867

7 February 2018

published in

Pharmacogenomics

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28975867%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

volume

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28975867%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

issue

15

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28975867%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

page(s)

1413-1425

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28975867%20AND%20SRC:MED&resulttype=core&format=json

Pharmacotherapy of traumatic brain injury: state of the science and the road forward: report of the Department of Defense Neurotrauma Pharmacology Workgroup

1 June 2020

cites work

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Pathophysiology Associated with Traumatic Brain Injury: Current Treatments and Potential Novel Therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Animal modelling of traumatic brain injury in preclinical drug development: where do we go from here?

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

A Rehabilomics focused perspective on molecular mechanisms underlying neurological injury, complications, and recovery after severe TBI.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Human Serum Metabolites Associate With Severity and Patient Outcomes in Traumatic Brain Injury

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Post-Traumatic Brain Injury: Genetic Susceptibility to Outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Genetic predisposition to adverse drug reactions in the intensive care unit

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

HGVS Recommendations for the Description of Sequence Variants: 2016 Update

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Genenames.org: the HGNC resources in 2015

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

The blood-brain barrier: an overview: structure, regulation, and clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Pharmacogenomics of membrane transporters: past, present and future

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Influence of ATP-binding cassette polymorphisms on neurological outcome after traumatic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Effect of single nucleotide polymorphisms in the ATP-binding cassette B1 gene on the clinical outcome of traumatic brain injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

ABCG2 c.421C>A is Associated with Outcomes Following Severe Traumatic Brain Injury

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Optimizing sedation in patients with acute brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Pharmacogenetics: from bench to byte--an update of guidelines

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Clinical pharmacogenetics implementation consortium guidelines for CYP2C9 and HLA-B genotypes and phenytoin dosing

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Critical Care Management of the Patient with Traumatic Brain Injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

A randomized, double-blind study of phenytoin for the prevention of post-traumatic seizures

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Should Levetiracetam or Phenytoin Be Used for Posttraumatic Seizure Prophylaxis? A Systematic Review of the Literature and Meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Neuroprotective, neuroplastic, and neurobehavioral effects of daily treatment with levetiracetam in experimental traumatic brain injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Abbreviated levetiracetam treatment effects on behavioural and histological outcomes after experimental TBI.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

CYP2C9, CYP2C19, ABCB1 (MDR1) genetic polymorphisms and phenytoin metabolism in a Black Beninese population

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Genetic predictors of the maximum doses patients receive during clinical use of the anti-epileptic drugs carbamazepine and phenytoin

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Adenosine A1 receptor knockout mice develop lethal status epilepticus after experimental traumatic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Adenosine A1 receptor activation as a brake on the microglial response after experimental traumatic brain injury in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Genetic variability in glutamic acid decarboxylase genes: associations with post-traumatic seizures after severe TBI.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Haptoglobin phenotype and apolipoprotein E polymorphism: relationship to posttraumatic seizures and neuropsychological functioning after traumatic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

The role of apolipoprotein E episilon (ε)-4 allele on outcome following traumatic brain injury: A systematic review

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Effect of the CYP3A5 genotype on the pharmacokinetics of intravenous midazolam during inhibited and induced metabolic states.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Chemical inhibitors of cytochrome P450 isoforms in human liver microsomes: a re-evaluation of P450 isoform selectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Factors predisposing to coma and delirium: fentanyl and midazolam exposure; CYP3A5, ABCB1, and ABCG2 genetic polymorphisms; and inflammatory factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Effectiveness of ketamine in decreasing intracranial pressure in children with intracranial hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Contribution of CYP3A4, CYP2B6, and CYP2C9 isoforms to N-demethylation of ketamine in human liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

CYP2B6*6 allele and age substantially reduce steady-state ketamine clearance in chronic pain patients: impact on adverse effects

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Ketamine: A Review of Clinical Pharmacokinetics and Pharmacodynamics in Anesthesia and Pain Therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Interpatient variability in dexmedetomidine response: a survey of the literature

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

The role of the ADRA2A C1291G genetic polymorphism in response to dexmedetomidine on patients undergoing coronary artery surgery.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Cross-sectional analysis of the influence of currently known pharmacogenetic modulators on opioid therapy in outpatient pain centers

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Impact of CYP3A5 and ABCB1 gene polymorphisms on fentanyl pharmacokinetics and clinical responses in cancer patients undergoing conversion to a transdermal system.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

ABCB1 genotype is associated with fentanyl requirements in critically ill children

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

µ-opioid receptor gene variant OPRM1 118 A>G: a summary of its molecular and clinical consequences for pain

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

A Dopamine Pathway Gene Risk Score for Cognitive Recovery Following Traumatic Brain Injury: Methodological Considerations, Preliminary Findings, and Interactions With Sex.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Updates and Current Perspectives of Psychiatric Assessments after Traumatic Brain Injury: A Systematic Review

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Post-traumatic epilepsy: current and emerging treatment options

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Rates of major depressive disorder and clinical outcomes following traumatic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

The sequenced treatment alternatives to relieve depression (STAR*D) trial: a review.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Variants of SLC6A4 in depression risk following severe TBI.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and CYP2C19 Genotypes and Dosing of Selective Serotonin Reuptake Inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Molecular mechanisms of cognitive dysfunction following traumatic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Pharmacotherapy for chronic cognitive impairment in traumatic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Posttraumatic Brain Injury Cognitive Performance Is Moderated by Variation Within ANKK1 and DRD2 Genes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Association of KIBRA rs17070145 polymorphism and episodic memory in individuals with severe TBI.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Genetic Variation in the Vesicular Monoamine Transporter: Preliminary Associations With Cognitive Outcomes After Severe Traumatic Brain Injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Influence of Catechol-O-methyltransferase on Executive Functioning Longitudinally After Early Childhood Traumatic Brain Injury: Preliminary Findings

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

COMT and ANKK1 Genetics Interact With Depression to Influence Behavior Following Severe TBI: An Initial Assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

COMT Val 158 Met polymorphism is associated with nonverbal cognition following mild traumatic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

COMT Val158Met polymorphism is associated with post-traumatic stress disorder and functional outcome following mild traumatic brain injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

PharmGKB summary: dopamine receptor D2

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Methylphenidate and Memory and Attention Adaptation Training for Persistent Cognitive Symptoms after Traumatic Brain Injury: A Randomized, Placebo-Controlled Trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Homocysteine and neurologic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

MTHFR C677T genotype as a risk factor for epilepsy including post-traumatic epilepsy in a representative military cohort.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Genetic variation in the adenosine regulatory cycle is associated with posttraumatic epilepsy development

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Genetic variation in neuronal glutamate transport genes and associations with posttraumatic seizure.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Pharmacological treatments for preventing epilepsy following traumatic head injury

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Key role of sulfonylurea receptor 1 in progressive secondary hemorrhage after brain contusion

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Molecular mechanisms of microvascular failure in central nervous system injury--synergistic roles of NKCC1 and SUR1/TRPM4.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Perspectives on molecular biomarkers of oxidative stress and antioxidant strategies in traumatic brain injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Sulfonylurea Receptor 1 in Humans with Post-Traumatic Brain Contusions

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Assessment of antioxidant reserves and oxidative stress in cerebrospinal fluid after severe traumatic brain injury in infants and children

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Traumatic brain injury: oxidative stress and neuroprotection.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Safety and efficacy of uric acid in patients with acute stroke (URICO-ICTUS): a randomised, double-blind phase 2b/3 trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Intracranial pressure: to monitor or not to monitor? A review of our experience with severe head injury

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Safety and efficacy of intravenous glyburide on brain swelling after large hemispheric infarction (GAMES-RP): a randomised, double-blind, placebo-controlled phase 2 trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

ABCC8 Single Nucleotide Polymorphisms are Associated with Cerebral Edema in Severe TBI.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Aquaporin-4: A Potential Therapeutic Target for Cerebral Edema

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

AQP4 tag single nucleotide polymorphisms in patients with traumatic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

20-HETE is associated with unfavorable outcomes in subarachnoid hemorrhage patients

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

Pharmacogenomics and pharmacogenetics for the intensive care unit: a narrative review.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5694019

Guidelines for the Management of Severe Traumatic Brain Injury, Fourth Edition

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5694019

Probenecid, an organic anion transporter 1 and 3 inhibitor, increases plasma and brain exposure of N-acetylcysteine

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5694019

The pharmacogenomics of pain management: prospects for personalized medicine

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5694019

Drug and xenobiotic biotransformation in the blood-brain barrier: a neglected issue.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5694019

Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents--second edition.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5694019

Surveillance for traumatic brain injury-related deaths--United States, 1997-2007.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5694019

Adenosine A1 receptor gene variants associated with post-traumatic seizures after severe TBI.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5694019

Nonconvulsive electrographic seizures after traumatic brain injury result in a delayed, prolonged increase in intracranial pressure and metabolic crisis

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5694019

Guidelines for the management of severe traumatic brain injury. XI. Anesthetics, analgesics, and sedatives.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5694019

Association of Multidrug Resistance in Epilepsy with a Polymorphism in the Drug-Transporter GeneABCB1

2 November 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS-2017-0073

TBI translational rehabilitation research in the 21st Century: exploring a Rehabilomics research model

21 January 2018

1 reference

12 December 2020

APOE genetic associations with seizure development after severe traumatic brain injury

1 reference

12 December 2020

IL-1β associations with posttraumatic epilepsy development: A genetics and biomarker cohort study

1 reference

12 December 2020

Rehabilomics research: a model for translational rehabilitation and comparative effectiveness rehabilitation research

1 reference

12 December 2020

Pathophysiology of traumatic brain injury

1 reference

12 December 2020

Identifiers

DOI

10.2217/PGS-2017-0073

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28975867%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28975867%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference