(Q48071843)

8 February 2018

title

Yap-dependent reprogramming of Lgr5(+) stem cells drives intestinal regeneration and cancer (English)

1 reference

8 February 2018

1

Alex Gregorieff

1 reference

8 February 2018

Jeffrey L. Wrana

5

object named as

Jeffrey L Wrana

1 reference

8 February 2018

author name string

Yu Liu

2

1 reference

8 February 2018

Mohammad R Inanlou

3

1 reference

8 February 2018

Yuliya Khomchuk

4

1 reference

8 February 2018

language of work or name

English

0 references

publication date

21 October 2015

1 reference

8 February 2018

published in

Nature

1 reference

8 February 2018

volume

526

1 reference

8 February 2018

issue

7575

1 reference

8 February 2018

page(s)

715-718

1 reference

8 February 2018

The intestinal crypt, a prototype stem cell compartment

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNATURE15382

The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE15382

Hippo pathway regulation of gastrointestinal tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE15382

Restriction of intestinal stem cell expansion and the regenerative response by YAP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE15382

Lgr5+ stem cells are indispensable for radiation-induced intestinal regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE15382

Identification of stem cells in small intestine and colon by marker gene Lgr5

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE15382

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE15382

The Hippo pathway regulates Wnt/beta-catenin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE15382

A molecular mechanism that links Hippo signalling to the inhibition of Wnt/β-catenin signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE15382

YAP/TAZ incorporation in the β-catenin destruction complex orchestrates the Wnt response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE15382

The intestinal stem cell markers Bmi1 and Lgr5 identify two functionally distinct populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE15382

Dll1+ secretory progenitor cells revert to stem cells upon crypt damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE15382

Wnt signalling induces maturation of Paneth cells in intestinal crypts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE15382

Crypt-restricted proliferation and commitment to the Paneth cell lineage following Apc loss in the mouse intestine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE15382

Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE15382

Redundant sources of Wnt regulate intestinal stem cells and promote formation of Paneth cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE15382

TWEAK/Fn14 signaling is required for liver regeneration after partial hepatectomy in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE15382

Amphiregulin promotes intestinal epithelial regeneration: roles of intestinal subepithelial myofibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE15382

Hippo signaling regulates Drosophila intestine stem cell proliferation through multiple pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE15382

The pan-ErbB negative regulator Lrig1 is an intestinal stem cell marker that functions as a tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE15382

Warts and Yorkie Mediate Intestinal Regeneration by Influencing Stem Cell Proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE15382

Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE15382

TAZ induces growth factor-independent proliferation through activation of EGFR ligand amphiregulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE15382

YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE15382

The epidermal growth factor receptor system in skin repair and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE15382

Epiregulin is not essential for development of intestinal tumors but is required for protection from intestinal damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE15382

Tumor fibroblast-derived epiregulin promotes growth of colitis-associated neoplasms through ERK

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE15382

mTORC1-mediated translational elongation limits intestinal tumour initiation and growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE15382

Yap- and Cdc42-dependent nephrogenesis and morphogenesis during mouse kidney development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE15382

Multicolor fluorescent in situ hybridization to define abutting and overlapping gene expression in the embryonic zebrafish brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE15382

Multiplex detection of RNA expression in Drosophila embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE15382

Multichannel wholemount fluorescent and fluorescent/chromogenic in situ hybridization in Xenopus embryos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE15382

Expression pattern of Wnt signaling components in the adult intestine.

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26503053

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Wnt activity and basal niche position sensitize intestinal stem and progenitor cells to DNA damage.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26503053

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE15382

1 reference

8 February 2018

Dimensions Publication ID

1017213436

0 references

1 reference

8 February 2018