(Q48091190)

8 February 2018

title

Hypothesis on the relationship between the change in intracellular pH and incidence of sporadic Alzheimer's disease or vascular dementia. (English)

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8 February 2018

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Boyan Fang

1

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8 February 2018

Dajiang Wang

2

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8 February 2018

Meifeng Huang

3

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8 February 2018

Guohua Yu

4

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8 February 2018

Hua Li

5

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8 February 2018

publication date

1 September 2010

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8 February 2018

International Journal of Neuroscience

published in

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8 February 2018

volume

120

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8 February 2018

issue

9

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8 February 2018

page(s)

591-595

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8 February 2018

Insulin-degrading enzyme and Alzheimer disease: a genetic association study in the Han Chinese.

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BACE2, a beta -secretase homolog, cleaves at the beta site and within the amyloid-beta region of the amyloid-beta precursor protein

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Are cancer cells acidic?

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Mechanisms of Abeta clearance and catabolism

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An integral approach to the etiopathogenesis of human neurodegenerative diseases (HNDDs) and cancer. Possible therapeutic consequences within the frame of the trophic factor withdrawal syndrome (TFWS).

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Growth and trophic factors, pH and the Na+/H+ exchanger in Alzheimer's disease, other neurodegenerative diseases and cancer: new therapeutic possibilities and potential dangers.

21 January 2018

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Amiloride kills malignant glioma cells independent of its inhibition of the sodium-hydrogen exchanger

21 January 2018

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Total inactivation of gamma-secretase activity in presenilin-deficient embryonic stem cells.

21 January 2018

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sigma-1 receptor modulation of acid-sensing ion channel a (ASIC1a) and ASIC1a-induced Ca2+ influx in rat cortical neurons

21 January 2018

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Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase

21 January 2018

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Distinct pH homeostatic features in lymphoblasts from Alzheimer's disease patients.

21 January 2018

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Immunolocalization of the acid-sensing ion channel 2a in the rat cerebellum.

21 January 2018

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Constitutive and regulated alpha-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease

21 January 2018

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Exploring the etiology of Alzheimer disease using molecular genetics

21 January 2018

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21 January 2018

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Physiological role and regulation of the Na+/H+ exchanger

21 January 2018

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Abeta 42-induced increase in neprilysin is associated with prevention of amyloid plaque formation in vivo.

21 January 2018

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21 January 2018

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Phosphoinositide 3-kinase is involved in the tumor-specific activation of human breast cancer cell Na(+)/H(+) exchange, motility, and invasion induced by serum deprivation

21 January 2018

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Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

21 January 2018

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Purification and cloning of amyloid precursor protein beta-secretase from human brain

21 January 2018

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Substrate activation of insulin-degrading enzyme (insulysin). A potential target for drug development.

21 January 2018

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Enhanced proliferation of lymphoblasts from patients with Alzheimer dementia associated with calmodulin-dependent activation of the na+/H+ exchanger.

21 January 2018

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Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

21 January 2018

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Acid-sensing ion channels (ASICs) as pharmacological targets for neurodegenerative diseases.

21 January 2018

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Hypoxia and reoxygenation increased BACE1 mRNA and protein levels in human neuroblastoma SH-SY5Y cells

21 January 2018

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https://api.crossref.org/works/10.3109%2F00207454.2010.505353

Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity

21 January 2018

1 reference

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Elevated beta-secretase expression and enzymatic activity detected in sporadic Alzheimer disease

21 January 2018

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Quantification and distribution of beta-secretase alternative splice variants in the rat and human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00207454.2010.505353

10.3109/00207454.2010.505353

21 January 2018

Identifiers

DOI

1 reference

8 February 2018

PubMed ID

20707633

1 reference

8 February 2018