(Q48121576)

http://europepmc.org/abstract/MED/26453748

8 February 2018

title

The Quantity of Autocrine IL-2 Governs the Expansion Potential of CD8+ T Cells. (English)

1 reference

http://europepmc.org/abstract/MED/26453748

8 February 2018

author

Suzanne P M Welten

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26453748%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Sandra A Vloemans

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26453748%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Ramon Arens

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26453748%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

author name string

Anke Redeker

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26453748%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Miranda R M Baert

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26453748%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Machteld M Tiemessen

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26453748%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Frank J T Staal

6

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26453748%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

language of work or name

English

0 references

publication date

9 October 2015

1 reference

http://europepmc.org/abstract/MED/26453748

8 February 2018

published in

Journal of Immunology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26453748%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

volume

195

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26453748%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26453748%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

page(s)

4792-4801

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26453748%20AND%20SRC:MED&resulttype=core&format=json

CD8+ T cell efficacy in vaccination and disease

4 June 2020

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Plasticity in programming of effector and memory CD8 T-cell formation

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Tolerance, not immunity, crucially depends on IL-2.

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Prolonged interleukin-2Ralpha expression on virus-specific CD8+ T cells favors terminal-effector differentiation in vivo.

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Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells

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Interleukin-2 signals during priming are required for secondary expansion of CD8+ memory T cells.

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Differential role of IL-2R signaling for CD8+ T cell responses in acute and chronic viral infections.

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CD27 sustains survival of CTLs in virus-infected nonlymphoid tissue in mice by inducing autocrine IL-2 production

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IL-2 is not required for the initiation of CD8 T cell cycling but sustains expansion

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Essential role for IL-2 in the regulation of antiviral extralymphoid CD8 T cell responses.

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Autocrine IL-2 is required for secondary population expansion of CD8(+) memory T cells

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T Cell factor 1 represses CD8+ effector T cell formation and function

21 January 2018

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Differential B7-CD28 costimulatory requirements for stable and inflationary mouse cytomegalovirus-specific memory CD8 T cell populations

21 January 2018

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Four distinct patterns of memory CD8 T cell responses to chronic murine cytomegalovirus infection

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Genome-wide analysis reveals a highly diverse CD8 T cell response to murine cytomegalovirus

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T cell receptor antagonist peptides induce positive selection

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Adoptive transfer of effector CD8+ T cells derived from central memory cells establishes persistent T cell memory in primates

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Serial transfer of single-cell-derived immunocompetence reveals stemness of CD8(+) central memory T cells

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Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

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Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major

21 January 2018

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Lineage relationship and protective immunity of memory CD8 T cell subsets

21 January 2018

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Mechanism of tumor rejection with doublets of CTLA-4, PD-1/PD-L1, or IDO blockade involves restored IL-2 production and proliferation of CD8(+) T cells directly within the tumor microenvironment

21 January 2018

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The stoichiometric production of IL-2 and IFN-γ mRNA defines memory T cells that can self-renew after adoptive transfer in humans.

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CD27 mediates interleukin-2-independent clonal expansion of the CD8+ T cell without effector differentiation.

21 January 2018

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21 January 2018

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Enhanced signaling through the IL-2 receptor in CD8+ T cells regulated by antigen recognition results in preferential proliferation and expansion of responding CD8+ T cells rather than promotion of cell death

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Regulatory CD4+CD25+ T cells restrict memory CD8+ T cell responses

21 January 2018

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CD25+CD4+ T cells contribute to the control of memory CD8+ T cells

21 January 2018

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CD4+CD25+ regulatory T cells control CD8+ T-cell effector differentiation by modulating IL-2 homeostasis

21 January 2018

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T-cell-receptor gene therapy

21 January 2018

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21 January 2018

Identifiers

DOI

10.4049/JIMMUNOL.1501083

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26453748%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

1 reference