(Q48121748)

8 February 2018

title

Reduced GABAergic inhibition explains cortical hyperexcitability in the wobbler mouse model of ALS. (English)

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8 February 2018

amyotrophic lateral sclerosis

main subject

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3

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8 February 2018

Jose Luis Nieto-Gonzalez

object named as

Jose Luis Nieto-Gonzalez

1

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author name string

Jakob Moser

2

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8 February 2018

Thomas Schmitt-John

4

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8 February 2018

Kimmo Jensen

5

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8 February 2018

publication date

19 July 2010

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8 February 2018

published in

Cerebral Cortex

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8 February 2018

volume

21

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8 February 2018

issue

3

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8 February 2018

page(s)

625-635

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8 February 2018

The Wobbler Mouse: A Neurodegeneration Jigsaw Puzzle

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1 reference

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Synaptic release generates a tonic GABA(A) receptor-mediated conductance that modulates burst precision in thalamic relay neurons.

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Pharmacologic reversal of cortical hyperexcitability in patients with ALS.

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GAB(A) receptors present higher affinity and modified subunit composition in spinal motor neurons from a genetic model of amyotrophic lateral sclerosis.

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Paraspinal and limb motor neuron involvement within homologous spinal segments in ALS

21 January 2018

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Variations on an inhibitory theme: phasic and tonic activation of GABA(A) receptors

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The Gene for Ciliary Neurotrophic Factor (CNTF) Maps to Murine Chromosome 19 and its Expression is Not Affected in the Hereditary Motoneuron Disease 'Wobbler' of the Mouse.

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21 January 2018

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21 January 2018

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Increased persistent sodium current determines cortical hyperexcitability in a genetic model of amyotrophic lateral sclerosis

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Evidence for chronic mitochondrial impairment in the cervical spinal cord of a murine model of motor neuron disease

21 January 2018

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21 January 2018

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21 January 2018

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Cell type-specific GABA A receptor-mediated tonic inhibition in mouse neocortex

21 January 2018

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Novel threshold tracking techniques suggest that cortical hyperexcitability is an early feature of motor neuron disease.

21 January 2018

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Cortical hyperexcitability may precede the onset of familial amyotrophic lateral sclerosis.

21 January 2018

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21 January 2018

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Changes in motor cortex inhibition over time in patients with amyotrophic lateral sclerosis

21 January 2018

1 reference

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Different mechanisms contribute to motor cortex hyperexcitability in amyotrophic lateral sclerosis

21 January 2018

1 reference

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Maturation of Layer V Pyramidal Neurons in the Rat Prefrontal Cortex: Intrinsic Properties and Synaptic Function

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCERCOR%2FBHQ134

Impaired motor cortex inhibition in patients with amyotrophic lateral sclerosis. Evidence from paired transcranial magnetic stimulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCERCOR%2FBHQ134

21 January 2018

Identifiers

DOI

10.1093/CERCOR/BHQ134

1 reference

8 February 2018

PubMed ID

20643756

1 reference

8 February 2018