(Q48132232)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28859225%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

title

Widespread brain distribution and activity following i.c.v. infusion of anti-β-secretase (BACE1) in nonhuman primates (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28859225%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

0 references

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28859225%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

author name string

Daniela Bumbaca Yadav

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28859225%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Janice A Maloney

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28859225%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Kristin R Wildsmith

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28859225%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Reina N Fuji

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28859225%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

William J Meilandt

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28859225%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Hilda Solanoy

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28859225%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Yanmei Lu

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28859225%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Kun Peng

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28859225%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Blair Wilson

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28859225%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Pamela Chan

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28859225%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Kapil Gadkar

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28859225%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Andrew Kosky

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28859225%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Marisa Goo

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28859225%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Ann Daugherty

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28859225%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Jessica A Couch

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28859225%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Thomas Keene

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28859225%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Karen Hayes

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28859225%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Lisa Jungbauer Nikolas

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28859225%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Deanna Lane

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28859225%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Robert Switzer

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28859225%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Eric Adams

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28859225%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Ryan J Watts

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28859225%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Kimberly Scearce-Levie

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28859225%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Saileta Prabhu

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28859225%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Lisa Shafer

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28859225%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Deepak R Thakker

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28859225%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Keith Hildebrand

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28859225%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

language of work or name

English

0 references

publication date

6 October 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28859225%20AND%20SRC:MED&resulttype=core&format=json

British Journal of Pharmacology

28 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28859225%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

volume

174

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28859225%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

issue

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28859225%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

page(s)

4173-4185

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28859225%20AND%20SRC:MED&resulttype=core&format=json

The Concise Guide to PHARMACOLOGY 2015/16: Enzymes

28 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659992

The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659992

A novel BACE inhibitor NB-360 shows a superior pharmacological profile and robust reduction of amyloid-β and neuroinflammation in APP transgenic mice

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659992

Experimental design and analysis and their reporting: new guidance for publication in BJP.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659992

Implementing guidelines on reporting research using animals (ARRIVE etc.): new requirements for publication in BJP.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659992

Centrally Delivered BACE1 Inhibitor Activates Microglia, and Reverses Amyloid Pathology and Cognitive Deficit in Aged Tg2576 Mice.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659992

Immunotherapeutic approaches for Alzheimer's disease

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659992

Safety and tolerability of intracerebroventricular PDGF-BB in Parkinson's disease patients

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659992

Antibodies to watch in 2015

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659992

Therapeutic bispecific antibodies cross the blood-brain barrier in nonhuman primates.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659992

Molecular mechanisms of Alzheimer disease protection by the A673T allele of amyloid precursor protein

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659992

Combined treatment with a BACE inhibitor and anti-Aβ antibody gantenerumab enhances amyloid reduction in APPLondon mice.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659992

Intrathecal delivery of protein therapeutics to the brain: a critical reassessment

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659992

Targeting the β secretase BACE1 for Alzheimer's disease therapy

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659992

Open questions for Alzheimer's disease immunotherapy

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659992

AZ-4217: a high potency BACE inhibitor displaying acute central efficacy in different in vivo models and reduced amyloid deposition in Tg2576 mice.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659992

Developing therapeutic antibodies for neurodegenerative disease

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659992

Diffusion of macromolecules in the brain: implications for drug delivery

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659992

A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid β.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659992

A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659992

Distribution of acid sphingomyelinase in rodent and non-human primate brain after intracerebroventricular infusion.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659992

A therapeutic antibody targeting BACE1 inhibits amyloid-β production in vivo

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659992

Animal research: reporting in vivo experiments: the ARRIVE guidelines

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659992

The perivascular astroglial sheath provides a complete covering of the brain microvessels: an electron microscopic 3D reconstruction

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659992

Intracerebroventricular amyloid-beta antibodies reduce cerebral amyloid angiopathy and associated micro-hemorrhages in aged Tg2576 mice

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659992

Intracerebroventricular infusion of acid sphingomyelinase corrects CNS manifestations in a mouse model of Niemann-Pick A disease

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659992

Rituximab levels in cerebrospinal fluid of patients with neurological autoimmune disorders.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659992

Perivascular drainage of amyloid-beta peptides from the brain and its failure in cerebral amyloid angiopathy and Alzheimer's disease.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659992

Anti-amyloid beta protein antibody passage across the blood-brain barrier in the SAMP8 mouse model of Alzheimer's disease: an age-related selective uptake with reversal of learning impairment

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659992

Intrathecally infused antibodies against Nogo-A penetrate the CNS and downregulate the endogenous neurite growth inhibitor Nogo-A.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659992

The "perivascular pump" driven by arterial pulsation is a powerful mechanism for the distribution of therapeutic molecules within the brain

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659992

Best-practice surgical techniques for intrathecal baclofen therapy.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659992

Mechanisms to explain the reverse perivascular transport of solutes out of the brain.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659992

Microglial activation facilitates Abeta plaque removal following intracranial anti-Abeta antibody administration

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659992

Intracranially Administered Anti-Αβ Antibodies Reduce β-Amyloid Deposition by Mechanisms Both Independent of and Associated with Microglial Activation

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659992

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659992

Delivery of peptides and proteins through the blood-brain barrier

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659992

Implantable pumps for drug delivery to the brain

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659992

Use of implantable pump systems for intraarterial, intraventricular and intratumoral treatment of malignant brain tumors

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659992

26 August 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/28859225

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Long-term intraventricular infusion of morphine for intractable pain in cancer of the head and neck

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28859225

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Continuous intraventricular morphine- or peptide-infusion for intractable cancer pain

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28859225

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/BPH.14021

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28859225%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28859225%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

1 reference