(Q30486176)

18 August 2017

Intracerebroventricular amyloid-beta antibodies reduce cerebral amyloid angiopathy and associated micro-hemorrhages in aged Tg2576 mice (English)

1 reference

cerebral amyloid angiopathy

18 August 2017

0 references

1 reference

1 reference

Deepak R Thakker

1

1 reference

18 August 2017

Marcy R Weatherspoon

2

1 reference

18 August 2017

Jonathan Harrison

3

1 reference

18 August 2017

Thomas E Keene

4

1 reference

18 August 2017

Deanna S Lane

5

1 reference

18 August 2017

William F Kaemmerer

6

1 reference

18 August 2017

Gregory R Stewart

7

1 reference

18 August 2017

Lisa L Shafer

8

1 reference

18 August 2017

language of work or name

English

0 references

publication date

25 February 2009

1 reference

Proceedings of the National Academy of Sciences of the United States of America

18 August 2017

1 reference

18 August 2017

106

1 reference

18 August 2017

11

1 reference

18 August 2017

4501-4506

1 reference

Amyloid beta protein dimer-containing human CSF disrupts synaptic plasticity: prevention by systemic passive immunization

18 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647980

Reduced pathology and improved behavioral performance in Alzheimer's disease mice vaccinated with HSV amplicons expressing amyloid-beta and interleukin-4.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647980

Active and passive immunotherapy for neurodegenerative disorders

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647980

Deletion of tumor necrosis factor death receptor inhibits amyloid beta generation and prevents learning and memory deficits in Alzheimer's mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647980

TgCRND8 amyloid precursor protein transgenic mice exhibit an altered gamma-secretase processing and an aggressive, additive amyloid pathology subject to immunotherapeutic modulation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647980

Anti-A beta 1-11 antibody binds to different beta-amyloid species, inhibits fibril formation, and disaggregates preformed fibrils but not the most toxic oligomers.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647980

Internalized antibodies to the Abeta domain of APP reduce neuronal Abeta and protect against synaptic alterations.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647980

Amyloid-beta peptide remnants in AN-1792-immunized Alzheimer's disease patients: a biochemical analysis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647980

Novel approaches for immunotherapeutic intervention in Alzheimer's disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647980

A specific amyloid-beta protein assembly in the brain impairs memory

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647980

Antibodies against beta-amyloid reduce Abeta oligomers, glycogen synthase kinase-3beta activation and tau phosphorylation in vivo and in vitro.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647980

Clinical effects of Abeta immunization (AN1792) in patients with AD in an interrupted trial.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647980

Exacerbation of cerebral amyloid angiopathy-associated microhemorrhage in amyloid precursor protein transgenic mice by immunotherapy is dependent on antibody recognition of deposited forms of amyloid beta.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647980

Passive immunotherapy against Abeta in aged APP-transgenic mice reverses cognitive deficits and depletes parenchymal amyloid deposits in spite of increased vascular amyloid and microhemorrhage

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647980

Neurochemical and behavioral consequences of widespread gene knockdown in the adult mouse brain by using nonviral RNA interference

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647980

Amyloid angiopathy-related vascular cognitive impairment.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647980

Epitope and isotype specificities of antibodies to beta -amyloid peptide for protection against Alzheimer's disease-like neuropathology

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647980

Amyloid-beta immunotherapy for Alzheimer's disease: the end of the beginning

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647980

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647980

Alzheimer disease and cerebrovascular pathology: an update

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647980

Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647980

Augmented senile plaque load in aged female beta-amyloid precursor protein-transgenic mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647980

Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647980

A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647980

Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647980

Biochemical detection of Abeta isoforms: implications for pathogenesis, diagnosis, and treatment of Alzheimer's disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647980

Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647980

Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647980

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647980

A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease

20 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813404106

Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813404106

Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: a case report.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813404106

Neuropathology and pathogenesis of encephalitis following amyloid-beta immunization in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813404106

Abeta vaccination effects on plaque pathology in the absence of encephalitis in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813404106

Abeta species removal after abeta42 immunization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813404106

Deglycosylated anti-amyloid-beta antibodies eliminate cognitive deficits and reduce parenchymal amyloid with minimal vascular consequences in aged amyloid precursor protein transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813404106

Cerebral hemorrhage after passive anti-Abeta immunotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813404106

Insights into the mechanisms of action of anti-Abeta antibodies in Alzheimer's disease mouse models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813404106

Evidence for peripheral clearance of cerebral Abeta protein following chronic, active Abeta immunization in PSAPP mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813404106

Passage of amyloid beta protein antibody across the blood-brain barrier in a mouse model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813404106

Amyloid beta protein immunotherapy neutralizes Abeta oligomers that disrupt synaptic plasticity in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813404106

Accelerated plaque accumulation, associative learning deficits, and up-regulation of alpha 7 nicotinic receptor protein in transgenic mice co-expressing mutant human presenilin 1 and amyloid precursor proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813404106

Generation of antibodies specific for beta-amyloid by vaccination of patients with Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813404106

Abeta42 immunization in Alzheimer's disease generates Abeta N-terminal antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813404106

Passive amyloid immunotherapy clears amyloid and transiently activates microglia in a transgenic mouse model of amyloid deposition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813404106

Kinetics of cerebral amyloid angiopathy progression in a transgenic mouse model of Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813404106

Progression of cerebral amyloid angiopathy in transgenic mouse models of Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813404106

Quantification of cerebral amyloid angiopathy and parenchymal amyloid plaques with Congo red histochemical stain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813404106

Distribution of intraventricularly administered antiamyloid-beta peptide (Abeta) antibody in the mouse brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813404106

Reversal of amyloid beta toxicity in Alzheimer's disease model Tg2576 by intraventricular antiamyloid beta antibody.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813404106

Alzheimer's disease: Moving towards a vaccine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813404106

Intracranial adeno-associated virus-mediated delivery of anti-pan amyloid beta, amyloid beta40, and amyloid beta42 single-chain variable fragments attenuates plaque pathology in amyloid precursor protein mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813404106

Antibody-mediated clearance of amyloid-beta peptide from cerebral amyloid angiopathy revealed by quantitative in vivo imaging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813404106

Microglial activation facilitates Abeta plaque removal following intracranial anti-Abeta antibody administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813404106

IgG-assisted age-dependent clearance of Alzheimer's amyloid beta peptide by the blood-brain barrier neonatal Fc receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813404106

Amyloid-beta in Alzheimer Disease: The Null versus the Alternate Hypotheses

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813404106

Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647980

Antibodies against beta-amyloid slow cognitive decline in Alzheimer's disease.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647980

Intracranially Administered Anti-Αβ Antibodies Reduce β-Amyloid Deposition by Mechanisms Both Independent of and Associated with Microglial Activation

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647980

Non-Fc-mediated mechanisms are involved in clearance of amyloid-beta in vivo by immunotherapy.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647980

Pathogenesis of cerebral amyloid angiopathy

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19246392

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Amyloid-beta immunization effectively reduces amyloid deposition in FcRgamma-/- knock-out mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19246392

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mechanisms of A beta plaque clearance following passive A beta immunization

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19246392

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0813404106

1 reference

18 August 2017

0 references

1 reference

18 August 2017

1 reference