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Immunotherapeutic approaches for Alzheimer's disease
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instance of
scholarly article
1 reference
stated in
PubMed
review article
1 reference
stated in
Europe PubMed Central
title
Immunotherapeutic approaches for Alzheimer's disease
(English)
1 reference
stated in
PubMed
main subject
Alzheimer's disease
1 reference
based on heuristic
inferred from title
immunotherapy
1 reference
based on heuristic
inferred from title
author
Thomas Wisniewski
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
4366618
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25789753%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 June 2020
author name string
Fernando Goñi
series ordinal
2
2 references
stated in
Crossref
stated in
Europe PubMed Central
PMC publication ID
4366618
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25789753%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 June 2020
language of work or name
English
1 reference
stated in
PubMed
publication date
18 March 2015
1 reference
stated in
PubMed
published in
Neuron
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMC publication ID
4366618
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25789753%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 June 2020
volume
85
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMC publication ID
4366618
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25789753%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 June 2020
issue
6
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMC publication ID
4366618
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25789753%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 June 2020
page(s)
1162-1176
1 reference
stated in
Europe PubMed Central
PMC publication ID
4366618
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25789753%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 June 2020
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29 September 2017
Disease modifying drugs targeting β-amyloid
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Safety, tolerability, and antibody response of active Aβ immunotherapy with CAD106 in patients with Alzheimer's disease: randomised, double-blind, placebo-controlled, first-in-human study
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29 September 2017
Active immunotherapy for Alzheimer's disease.
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29 September 2017
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29 September 2017
Could immunomodulation be used to prevent prion diseases?
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29 September 2017
Immunotherapy for Alzheimer's disease: from anti-β-amyloid to tau-based immunization strategies.
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29 September 2017
Amyloid-related imaging abnormalities in patients with Alzheimer's disease treated with bapineuzumab: a retrospective analysis
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Autosomal recessive causes likely in early-onset Alzheimer disease
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29 September 2017
Passive immunization with anti-Tau antibodies in two transgenic models: reduction of Tau pathology and delay of disease progression.
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29 September 2017
Passive immunization targeting pathological phospho-tau protein in a mouse model reduces functional decline and clears tau aggregates from the brain
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Prions.
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Immunotherapy for Alzheimer's disease
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Immunotherapy targeting pathological tau prevents cognitive decline in a new tangle mouse model
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Immunomodulation targeting abnormal protein conformation reduces pathology in a mouse model of Alzheimer's disease
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11C-PiB PET assessment of change in fibrillar amyloid-beta load in patients with Alzheimer's disease treated with bapineuzumab: a phase 2, double-blind, placebo-controlled, ascending-dose study
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29 September 2017
CD14 and toll-like receptors 2 and 4 are required for fibrillar A{beta}-stimulated microglial activation.
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29 September 2017
IV immunoglobulin is associated with a reduced risk of Alzheimer disease and related disorders
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29 September 2017
Prefilament tau species as potential targets for immunotherapy for Alzheimer disease and related disorders
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29 September 2017
Minocycline as a potential therapeutic agent in neurodegenerative disorders characterised by protein misfolding
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29 September 2017
Targeting generation of antibodies specific to conformational epitopes of amyloid beta-derived neurotoxins
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29 September 2017
Induction of toll-like receptor 9 signaling as a method for ameliorating Alzheimer's disease-related pathology
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29 September 2017
Immunotherapeutic applications of CpG oligodeoxynucleotide TLR9 agonists
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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29 September 2017
Linking Abeta and tau in late-onset Alzheimer's disease: a dual pathway hypothesis
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29 September 2017
Immunotherapy targeting pathological tau protein in Alzheimer's disease and related tauopathies.
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29 September 2017
Long-term effects of Abeta42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial
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29 September 2017
Alzheimer disease pathology as a host response
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29 September 2017
Toll-like receptor 4-dependent upregulation of cytokines in a transgenic mouse model of Alzheimer's disease
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29 September 2017
Ibuprofen reduces Abeta, hyperphosphorylated tau and memory deficits in Alzheimer mice
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29 September 2017
The role of the immune system in clearance of Abeta from the brain
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29 September 2017
Progress in the active immunotherapeutic approach to Alzheimer's disease: clinical investigations into AN1792-associated meningoencephalitis
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29 September 2017
Immunotherapy targeting pathological tau conformers in a tangle mouse model reduces brain pathology with associated functional improvements.
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29 September 2017
Disease modifying approaches for Alzheimer's pathology.
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29 September 2017
Anti-A beta 1-11 antibody binds to different beta-amyloid species, inhibits fibril formation, and disaggregates preformed fibrils but not the most toxic oligomers.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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29 September 2017
Liposomal vaccines with conformation-specific amyloid peptide antigens define immune response and efficacy in APP transgenic mice
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29 September 2017
Activation of microglia acidifies lysosomes and leads to degradation of Alzheimer amyloid fibrils
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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29 September 2017
Pathways by which Abeta facilitates tau pathology
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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29 September 2017
Vaccination of Alzheimer's model mice with Abeta derivative in alum adjuvant reduces Abeta burden without microhemorrhages
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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29 September 2017
A hundred years of Alzheimer's disease research
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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29 September 2017
Role of toll-like receptor signalling in Abeta uptake and clearance
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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29 September 2017
Chromosome 13 dementias
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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29 September 2017
Clinical effects of Abeta immunization (AN1792) in patients with AD in an interrupted trial.
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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29 September 2017
Immunological and anti-chaperone therapeutic approaches for Alzheimer disease
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29 September 2017
An attenuated immune response is sufficient to enhance cognition in an Alzheimer's disease mouse model immunized with amyloid-beta derivatives.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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29 September 2017
Epitope and isotype specificities of antibodies to beta -amyloid peptide for protection against Alzheimer's disease-like neuropathology
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29 September 2017
Tau-mediated cytotoxicity in a pseudohyperphosphorylation model of Alzheimer's disease.
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29 September 2017
Nasal vaccination with beta-amyloid peptide for the treatment of Alzheimer's disease
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29 September 2017
Immunization with a nontoxic/nonfibrillar amyloid-beta homologous peptide reduces Alzheimer's disease-associated pathology in transgenic mice
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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29 September 2017
Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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29 September 2017
Evidence that neurones accumulating amyloid can undergo lysis to form amyloid plaques in Alzheimer's disease
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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29 September 2017
A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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29 September 2017
Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline
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29 September 2017
Intraneuronal Abeta42 accumulation in human brain.
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29 September 2017
Disaggregation of Alzheimer beta-amyloid by site-directed mAb.
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29 September 2017
The pathogenesis of Alzheimer disease: an alternative to the amyloid hypothesis
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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29 September 2017
Molecular mechanisms of Alzheimer disease protection by the A673T allele of amyloid precursor protein
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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2 June 2018
Immunomodulation targeting of both Aβ and tau pathological conformers ameliorates Alzheimer's disease pathology in TgSwDI and 3xTg mouse models
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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2 June 2018
Anti-tau antibodies that block tau aggregate seeding in vitro markedly decrease pathology and improve cognition in vivo.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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2 June 2018
Passive anti-amyloid immunotherapy in Alzheimer's disease: What are the most promising targets?
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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2 June 2018
Apolipoprotein e: essential catalyst of the Alzheimer amyloid cascade
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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2 June 2018
Conformation-sensitive antibodies against alzheimer amyloid-beta by immunization with a thioredoxin-constrained B-cell epitope peptide
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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2 June 2018
Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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2 June 2018
The role of microglia in amyloid fibril formation.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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2 June 2018
Ultrastructure of the microglia that phagocytose amyloid and the microglia that produce beta-amyloid fibrils.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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2 June 2018
Ultrastructural studies of the cells forming amyloid in the cortical vessel wall in Alzheimer's disease
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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2 June 2018
Phase 3 trials of solanezumab for mild-to-moderate Alzheimer's disease
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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27 November 2018
Repeated immunization of mice with phosphorylated-tau peptides causes neuroinflammation
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27 November 2018
A plaque-specific antibody clears existing β-amyloid plaques in Alzheimer's disease mice.
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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27 November 2018
Longitudinal analysis of novel Alzheimer's disease proteomic cerebrospinal fluid biomarkers during intravenous immunoglobulin therapy.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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27 November 2018
An effector-reduced anti-β-amyloid (Aβ) antibody with unique aβ binding properties promotes neuroprotection and glial engulfment of Aβ.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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27 November 2018
Safety and biomarker effects of solanezumab in patients with Alzheimer's disease.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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27 November 2018
Tau pathology in children and young adults: can you still be unconditionally baptist?
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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27 November 2018
Beta-amyloid monomers are neuroprotective.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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27 November 2018
Anti-amyloid-beta immunotherapy in Alzheimer's disease: ACC-001 clinical trials are ongoing.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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27 November 2018
18-Month study of intravenous immunoglobulin for treatment of mild Alzheimer disease.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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27 November 2018
Absence of beta-amyloid deposits after immunization in Alzheimer disease with Lewy body dementia.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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27 November 2018
Monoclonal antibodies that target pathological assemblies of Abeta.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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27 November 2018
Abeta species removal after abeta42 immunization.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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27 November 2018
Tauopathy-like abnormalities and neurologic deficits in mice immunized with neuronal tau protein.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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27 November 2018
Targeting amyloid-beta peptide (Abeta) oligomers by passive immunization with a conformation-selective monoclonal antibody improves learning and memory in Abeta precursor protein (APP) transgenic mice.
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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27 November 2018
Temporal profile of amyloid-beta (Abeta) oligomerization in an in vivo model of Alzheimer disease. A link between Abeta and tau pathology
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27 November 2018
Ineffective phagocytosis of amyloid-beta by macrophages of Alzheimer's disease patients.
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27 November 2018
Effects of alpha-synuclein immunization in a mouse model of Parkinson's disease
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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27 November 2018
Abeta vaccination effects on plaque pathology in the absence of encephalitis in Alzheimer disease
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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27 November 2018
Evaluation of the safety and immunogenicity of synthetic A 42 (AN1792) in patients with AD
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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27 November 2018
Neuropathology and pathogenesis of encephalitis following amyloid-beta immunization in Alzheimer's disease
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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27 November 2018
Antibodies against beta-amyloid slow cognitive decline in Alzheimer's disease.
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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27 November 2018
Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: a case report.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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27 November 2018
Generation of antibodies specific for beta-amyloid by vaccination of patients with Alzheimer disease.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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27 November 2018
Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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27 November 2018
A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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27 November 2018
Neuropathological staging of Alzheimer lesions and intellectual status in Alzheimer's and Parkinson's disease patients.
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
retrieved
27 November 2018
Dominant and differential deposition of distinct beta-amyloid peptide species, A beta N3(pE), in senile plaques.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366618
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27 November 2018
Genetics of Alzheimer's disease
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27 November 2018
Immunotherapy for Alzheimer's disease
1 reference
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PubMed
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https://pubmed.ncbi.nlm.nih.gov/25789753
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Immunotherapy for Alzheimer's disease
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25789753
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The pathological process underlying Alzheimer's disease in individuals under thirty
1 reference
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PubMed
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https://pubmed.ncbi.nlm.nih.gov/25789753
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based on heuristic
inferred from PubMed ID database lookup
The genetics of Alzheimer's disease
1 reference
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https://pubmed.ncbi.nlm.nih.gov/25789753
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.NEURON.2014.12.064
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
131105
stated in
Europe PubMed Central
PMC publication ID
4366618
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25789753%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 June 2020
OpenCitations bibliographic resource ID
131105
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
131105
PMC publication ID
4366618
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
131105
stated in
Europe PubMed Central
PMC publication ID
4366618
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25789753%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 June 2020
PubMed publication ID
25789753
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
131105
stated in
Europe PubMed Central
PMC publication ID
4366618
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25789753%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 June 2020
ResearchGate publication ID
273781106
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