(Q47393680)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22787053%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

title

An effector-reduced anti-β-amyloid (Aβ) antibody with unique aβ binding properties promotes neuroprotection and glial engulfment of Aβ (English)

1 reference

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7 February 2020

1 reference

3

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7 February 2020

author name string

Oskar Adolfsson

1

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7 February 2020

Maria Pihlgren

2

1 reference

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7 February 2020

Yvan Varisco

4

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7 February 2020

Anna Lucia Buccarello

5

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7 February 2020

Katia Antoniello

6

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7 February 2020

Sophie Lohmann

7

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7 February 2020

Kasia Piorkowska

8

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7 February 2020

Valerie Gafner

9

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7 February 2020

Jasvinder K Atwal

10

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7 February 2020

Janice Maloney

11

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7 February 2020

Mark Chen

12

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7 February 2020

Alvin Gogineni

13

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7 February 2020

Robby M Weimer

14

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7 February 2020

Deborah L Mortensen

15

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7 February 2020

Michel Friesenhahn

16

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7 February 2020

Carole Ho

17

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7 February 2020

Robert Paul

18

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7 February 2020

Andrea Pfeifer

19

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7 February 2020

Andreas Muhs

20

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7 February 2020

Ryan J Watts

21

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7 February 2020

language of work or name

English

0 references

publication date

1 July 2012

1 reference

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7 February 2020

published in

Journal of Neuroscience

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7 February 2020

volume

32

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7 February 2020

issue

28

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7 February 2020

page(s)

9677-9689

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describes a project that uses

7 February 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6622286/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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High resolution mapping of the binding site on human IgG1 for Fc gamma RI, Fc gamma RII, Fc gamma RIII, and FcRn and design of IgG1 variants with improved binding to the Fc gamma R.

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Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

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12 December 2020

Block of long-term potentiation by naturally secreted and synthetic amyloid beta-peptide in hippocampal slices is mediated via activation of the kinases c-Jun N-terminal kinase, cyclin-dependent kinase 5, and p38 mitogen-activated protein kinase as

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12 December 2020

Passive immunotherapy against Abeta in aged APP-transgenic mice reverses cognitive deficits and depletes parenchymal amyloid deposits in spite of increased vascular amyloid and microhemorrhage

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Targeting amyloid-beta peptide (Abeta) oligomers by passive immunization with a conformation-selective monoclonal antibody improves learning and memory in Abeta precursor protein (APP) transgenic mice.

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Effects of secreted oligomers of amyloid beta-protein on hippocampal synaptic plasticity: a potent role for trimers

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Intracranial administration of deglycosylated C-terminal-specific anti-Abeta antibody efficiently clears amyloid plaques without activating microglia in amyloid-depositing transgenic mice

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12 December 2020

Deglycosylated anti-amyloid-beta antibodies eliminate cognitive deficits and reduce parenchymal amyloid with minimal vascular consequences in aged amyloid precursor protein transgenic mice.

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12 December 2020

Interleukin-1alpha stimulates non-amyloidogenic pathway by alpha-secretase (ADAM-10 and ADAM-17) cleavage of APP in human astrocytic cells involving p38 MAP kinase.

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12 December 2020

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

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12 December 2020

Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway

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12 December 2020

Requirement of aggregation propensity of Alzheimer amyloid peptides for neuronal cell surface binding

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12 December 2020

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12 December 2020

Oligomers of the amyloid-beta protein disrupt working memory: confirmation with two behavioral procedures.

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12 December 2020

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12 December 2020

Passive immunotherapy rapidly increases structural plasticity in a mouse model of Alzheimer disease

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12 December 2020

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12 December 2020

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HH domain of Alzheimer's disease Abeta provides structural basis for neuronal binding in PC12 and mouse cortical/hippocampal neurons

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12 December 2020

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12 December 2020

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12 December 2020

Point substitution in the central hydrophobic cluster of a human beta-amyloid congener disrupts peptide folding and abolishes plaque competence

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10.1523/JNEUROSCI.4742-11.2012

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22787053%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

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7 February 2020

PubMed publication ID

22787053

1 reference