(Q40090247)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17715348%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

title

Immunotherapy targeting pathological tau conformers in a tangle mouse model reduces brain pathology with associated functional improvements (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17715348%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

0 references

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17715348%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

author name string

Ayodeji A Asuni

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17715348%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Allal Boutajangout

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17715348%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

David Quartermain

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17715348%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

language of work or name

English

0 references

publication date

1 August 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17715348%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17715348%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

volume

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17715348%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

page(s)

9115-9129

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17715348%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

issue

34

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17715348%20AND%20SRC:MED&resulttype=core&format=json

Sequence requirements for formation of conformational variants of tau similar to those found in Alzheimer's disease.

3 January 2020

cites work

1 reference

12 December 2020

Inhibition of Alzheimer's beta-amyloid induced vasoactivity and proinflammatory response in microglia by a cGMP-dependent mechanism

1 reference

12 December 2020

Osmotic opening of the blood-brain barrier: principles, mechanism, and therapeutic applications

1 reference

12 December 2020

Circulating insulin-like growth factor I mediates effects of exercise on the brain.

1 reference

12 December 2020

Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein

1 reference

12 December 2020

Tau filament formation in transgenic mice expressing P301L tau.

1 reference

12 December 2020

Conformational change as one of the earliest alterations of tau in Alzheimer's disease.

1 reference

12 December 2020

Effect of experimental treatment on housekeeping gene expression: validation by real-time, quantitative RT-PCR.

1 reference

12 December 2020

Effects of FTDP-17 mutations on the in vitro phosphorylation of tau by glycogen synthase kinase 3beta identified by mass spectrometry demonstrate certain mutations exert long-range conformational changes

1 reference

12 December 2020

Immunization with a nontoxic/nonfibrillar amyloid-beta homologous peptide reduces Alzheimer's disease-associated pathology in transgenic mice

1 reference

12 December 2020

Permeability of proteins at the blood-brain barrier in the normal adult mouse and double transgenic mouse model of Alzheimer's disease.

1 reference

12 December 2020

Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP.

1 reference

12 December 2020

Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils

1 reference

12 December 2020

Radioimmunoassays for Ig classes G, A, M, D, and E in spinal fluids: normal values of different age groups

1 reference

12 December 2020

Immunoglobulin Fc gamma receptor promotes immunoglobulin uptake, immunoglobulin-mediated calcium increase, and neurotransmitter release in motor neurons

1 reference

12 December 2020

Nonoverlapping but synergetic tau and APP pathologies in sporadic Alzheimer's disease.

1 reference

12 December 2020

Amyloid-beta immunotherapy for Alzheimer's disease: the end of the beginning

1 reference

12 December 2020

Passage of amyloid beta protein antibody across the blood-brain barrier in a mouse model of Alzheimer's disease.

1 reference

12 December 2020

Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: a case report.

1 reference

12 December 2020

Detection of Alzheimer's amyloid in transgenic mice using magnetic resonance microimaging

1 reference

12 December 2020

Hydrofluoric acid-treated tau PHF proteins display the same biochemical properties as normal tau

1 reference

12 December 2020

Direct action of immunoglobulin G on primary sensory neurons through Fc gamma receptor I

1 reference

12 December 2020

Delineation of putative mechanisms involved in antibody-mediated clearance of rabies virus from the central nervous system

1 reference

12 December 2020

Neuropathology and pathogenesis of encephalitis following amyloid-beta immunization in Alzheimer's disease.

1 reference

12 December 2020

Tau protein and neurodegeneration

1 reference

12 December 2020

Low density lipoprotein receptor-related protein: regulation of the plasma membrane proteome

1 reference

12 December 2020

An attenuated immune response is sufficient to enhance cognition in an Alzheimer's disease mouse model immunized with amyloid-beta derivatives.

1 reference

12 December 2020

Inhibition of neurofibrillary degeneration: a promising approach to Alzheimer's disease and other tauopathies

1 reference

12 December 2020

Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome

1 reference

12 December 2020

Method for measurement of the blood-brain barrier permeability in the perfused mouse brain: application to amyloid-beta peptide in wild type and Alzheimer's Tg2576 mice

1 reference

12 December 2020

{beta}-Amyloid-induced neurodegeneration and protection by structurally diverse microtubule-stabilizing agents.

1 reference

12 December 2020

Antibody pharmacokinetics and pharmacodynamics

1 reference

12 December 2020

Anthraquinones inhibit tau aggregation and dissolve Alzheimer's paired helical filaments in vitro and in cells

1 reference

12 December 2020

Microtubule-binding drugs offset tau sequestration by stabilizing microtubules and reversing fast axonal transport deficits in a tauopathy model

1 reference

12 December 2020

Abeta vaccination effects on plaque pathology in the absence of encephalitis in Alzheimer disease

1 reference

12 December 2020

Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo

1 reference

12 December 2020

Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms.

1 reference

12 December 2020

Effects of alpha-synuclein immunization in a mouse model of Parkinson's disease

1 reference

12 December 2020

Development of a high throughput drug screening assay for the detection of changes in tau levels -- proof of concept with HSP90 inhibitors

1 reference

12 December 2020

Histological staining of amyloid-beta in mouse brains

1 reference

12 December 2020

Tau suppression in a neurodegenerative mouse model improves memory function

1 reference

12 December 2020

Accelerated amyloid deposition, neurofibrillary degeneration and neuronal loss in double mutant APP/tau transgenic mice.

1 reference

12 December 2020

Region-specific dissociation of neuronal loss and neurofibrillary pathology in a mouse model of tauopathy

1 reference

12 December 2020

Immunotherapy for conformational diseases.

1 reference

12 December 2020

A saturable mechanism for transport of immunoglobulin G across the blood-brain barrier of the guinea pig

1 reference

12 December 2020

Uptake of antineuronal IgM by CNS neurons: comparison with antineuronal IgG.

1 reference

12 December 2020

Vaccination of Alzheimer's model mice with Abeta derivative in alum adjuvant reduces Abeta burden without microhemorrhages

1 reference

12 December 2020

Abnormal bundling and accumulation of F-actin mediates tau-induced neuronal degeneration in vivo.

1 reference

12 December 2020

A non-toxic ligand for voxel-based MRI analysis of plaques in AD transgenic mice

1 reference

12 December 2020

Internalized antibodies to the Abeta domain of APP reduce neuronal Abeta and protect against synaptic alterations.

1 reference

12 December 2020

Low density lipoprotein receptor-related protein mediates endocytosis of monoclonal antibodies in cultured cells and rabbit liver.

1 reference

12 December 2020

Intraneuronal IgG in the central nervous system: uptake by retrograde axonal transport

1 reference

12 December 2020

Immunohistochemical localization of intracellular plasma proteins in the human central nervous system

1 reference

12 December 2020

Intraneuronal IgG in the central nervous system.

1 reference

12 December 2020

Conjugation of fluorescein isothiocyanate to antibodies. II. A reproducible method

1 reference

12 December 2020

Monoclonal antibody PHF-1 recognizes tau protein phosphorylated at serine residues 396 and 404.

1 reference

12 December 2020

1 reference

12 December 2020

Behavioural, histochemical and biochemical consequences of selective immunolesions in discrete regions of the basal forebrain cholinergic system

1 reference

12 December 2020

Neuropathological changes in Alzheimer disease

1 reference

12 December 2020

Immunocytochemical localization of immunoglobulins in the rat brain: relationship to the blood-brain barrier

1 reference

12 December 2020

The distribution of Alz-50 immunoreactivity in the normal human brain

1 reference

12 December 2020

Serum proteins bypass the blood-brain fluid barriers for extracellular entry to the central nervous system.

1 reference

12 December 2020

Alz-50 and MC-1, a new monoclonal antibody raised to paired helical filaments, recognize conformational epitopes on recombinant tau.

1 reference

12 December 2020

Increased neuronal endocytosis and protease delivery to early endosomes in sporadic Alzheimer's disease: neuropathologic evidence for a mechanism of increased beta-amyloidogenesis.

1 reference

12 December 2020

Local and distant histopathological effects of unilateral amyloid-beta 25-35 injections into the amygdala of young F344 rats.

1 reference

12 December 2020

Bilateral injections of amyloid-beta 25-35 into the amygdala of young Fischer rats: behavioral, neurochemical, and time dependent histopathological effects

1 reference

12 December 2020

Frontotemporal dementia and Parkinsonism linked to chromosome 17: a new group of tauopathies.

1 reference

12 December 2020

Tau is a candidate gene for chromosome 17 frontotemporal dementia

1 reference

12 December 2020

Antigen-dependent intrathecal antibody synthesis in the normal rat brain: tissue entry and local retention of antigen-specific B cells.

1 reference

12 December 2020

10.1523/JNEUROSCI.2361-07.2007

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17715348%20AND%20SRC:MED&resulttype=core&format=json

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3 January 2020

Fatcat ID

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Fatcat

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24 November 2022

mapped directly with Wikidata item

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17715348%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

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