(Q48137958)

9 February 2018

title

Impaired dynamics and function of mitochondria caused by mtDNA toxicity leads to heart failure (English)

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9 February 2018

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9 February 2018

Linda H Bergersen

object named as

Linda H Bergersen

12

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Håvard Attramadal

object named as

Håvard Attramadal

10

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Arne Klungland

8

object named as

Arne Klungland

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9 February 2018

7

Ivar Sjaastad

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9 February 2018

3

Jan Magnus Aronsen

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9 February 2018

11

Jon Storm-Mathisen

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9 February 2018

Knut H Lauritzen

1

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9 February 2018

Liv Kleppa

2

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9 February 2018

Lars Eide

4

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9 February 2018

Harald Carlsen

5

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9 February 2018

Øyvind P Haugen

6

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9 February 2018

publication date

8 June 2015

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9 February 2018

American Journal of Physiology Heart and Circulatory Physiology

published in

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9 February 2018

volume

309

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9 February 2018

issue

3

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9 February 2018

page(s)

H434-49

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9 February 2018

Co-regulation of two gene activities by tetracycline via a bidirectional promoter.

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Mitochondria as a therapeutic target in heart failure

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Human mitochondrial uracil-DNA glycosylase preform (UNG1) is processed to two forms one of which is resistant to inhibition by AP sites

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OPA1 mutation and late-onset cardiomyopathy: mitochondrial dysfunction and mtDNA instability

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Mitochondrial dynamics in heart disease

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Morphological dynamics of mitochondria--a special emphasis on cardiac muscle cells

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Cytosolic p53 inhibits Parkin-mediated mitophagy and promotes mitochondrial dysfunction in the mouse heart

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Mitochondrial DNA damage and dysfunction associated with oxidative stress in failing hearts after myocardial infarction

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Mitochondrial DNA maintenance in yeast requires a protein containing a region related to the GTP-binding domain of dynamin

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Modeling the impact of mitochondrial DNA damage in forebrain neurons and beyond

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Mitochondrial DNA toxicity in forebrain neurons causes apoptosis, neurodegeneration, and impaired behavior

21 January 2018

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Decreased mtDNA, oxidative stress, cardiomyopathy, and death from transgenic cardiac targeted human mutant polymerase gamma.

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Different extent of cardiac malfunction and resistance to oxidative stress in heterozygous and homozygous manganese-dependent superoxide dismutase-mutant mice

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PGC-1 alpha regulates expression of myocardial mitochondrial antioxidants and myocardial oxidative stress after chronic systolic overload

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A role for peroxisome proliferator-activated receptor γ coactivator-1 in the control of mitochondrial dynamics during postnatal cardiac growth

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Role of mitochondrial dysfunction and altered autophagy in cardiovascular aging and disease: from mechanisms to therapeutics.

21 January 2018

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Inducible and neuron-specific gene expression in the adult mouse brain with the rtTA2S-M2 system.

21 January 2018

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Temporal trends in ischemic heart disease mortality in 21 world regions, 1980 to 2010: the Global Burden of Disease 2010 study

21 January 2018

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Nuclear and mitochondrial uracil-DNA glycosylases are generated by alternative splicing and transcription from different positions in the UNG gene

21 January 2018

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Apoptosis predominates in nonmyocytes in heart failure

21 January 2018

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Mitochondrial dynamics in the adult cardiomyocytes: which roles for a highly specialized cell?

21 January 2018

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Roles of histone deacetylation and AMP kinase in regulation of cardiomyocyte PGC-1α gene expression in hypoxia.

21 January 2018

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Natural selection of mitochondria during somatic lifetime promotes healthy aging

21 January 2018

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Mitochondria in cardiac hypertrophy and heart failure

21 January 2018

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Induction of mitochondrial biogenesis is a maladaptive mechanism in mitochondrial cardiomyopathies

21 January 2018

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Nuclear and mitochondrial forms of human uracil-DNA glycosylase are encoded by the same gene

21 January 2018

1 reference

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Cardiac-specific over-expression of epidermal growth factor receptor 2 (ErbB2) induces pro-survival pathways and hypertrophic cardiomyopathy in mice

21 January 2018

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Premature ageing in mice expressing defective mitochondrial DNA polymerase

21 January 2018

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Codon optimization markedly improves doxycycline regulated gene expression in the mouse heart

21 January 2018

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Mitochondrial biogenesis: pharmacological approaches

21 January 2018

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Cardiac overexpression of 8-oxoguanine DNA glycosylase 1 protects mitochondrial DNA and reduces cardiac fibrosis following transaortic constriction

21 January 2018

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Mitochondrial fission, fusion, and stress

21 January 2018

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Mitochondrial DNA mutations activate the mitochondrial apoptotic pathway and cause dilated cardiomyopathy.

21 January 2018

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Elevated Levels of 8-iso-Prostaglandin F 2α in Pericardial Fluid of Patients With Heart Failure

21 January 2018

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10.1152/AJPHEART.00253.2014

21 January 2018

Identifiers

DOI

1 reference

9 February 2018

1 reference

9 February 2018