(Q48207784)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29021346%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

title

The HECT E3 ubiquitin ligase NEDD4 interacts with and ubiquitylates SQSTM1 for inclusion body autophagy (English)

1 reference

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6 April 2020

1 reference

1 reference

1

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6 April 2020

Wannian Yang

10

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6 April 2020

author name string

Qian Dai

2

1 reference

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6 April 2020

Hongxia Meng

3

1 reference

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6 April 2020

Aiqin Sun

4

1 reference

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6 April 2020

Jing Wei

5

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6 April 2020

Ke Peng

6

1 reference

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6 April 2020

Chandra Childress

7

1 reference

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6 April 2020

Miao Chen

8

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6 April 2020

Genbao Shao

9

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6 April 2020

language of work or name

English

0 references

publication date

11 October 2017

1 reference

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6 April 2020

published in

Journal of Cell Science

1 reference

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6 April 2020

volume

130

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6 April 2020

issue

22

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6 April 2020

page(s)

3839-3850

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p62, Ref(2)P and ubiquitinated proteins are conserved markers of neuronal aging, aggregate formation and progressive autophagic defects.

6 April 2020

cites work

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p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

21 January 2018

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Monitoring autophagic degradation of p62/SQSTM1.

21 January 2018

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Identification and rescue of α-synuclein toxicity in Parkinson patient-derived neurons

21 January 2018

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Genetic variability in SQSTM1 and risk of early-onset Alzheimer dementia: a European early-onset dementia consortium study

21 January 2018

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Oxidative damage to the promoter region of SQSTM1/p62 is common to neurodegenerative disease

21 January 2018

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Keap1 facilitates p62-mediated ubiquitin aggregate clearance via autophagy

21 January 2018

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Development of "substrate-trapping" mutants to identify physiological substrates of protein tyrosine phosphatases

21 January 2018

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The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome

21 January 2018

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PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

21 January 2018

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TRAF6 mediates ubiquitination of KIF23/MKLP1 and is required for midbody ring degradation by selective autophagy.

21 January 2018

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Dissection of the role of p62/Sqstm1 in activation of Nrf2 during xenophagy.

21 January 2018

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p62 Targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding

21 January 2018

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Selective autophagy mediated by autophagic adapter proteins

21 January 2018

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Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomes

21 January 2018

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A role for ubiquitin in selective autophagy

21 January 2018

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A role for NBR1 in autophagosomal degradation of ubiquitinated substrates

21 January 2018

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Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice

21 January 2018

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Early accumulation of p62 in neurofibrillary tangles in Alzheimer's disease: possible role in tangle formation.

21 January 2018

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Interaction codes within the family of mammalian Phox and Bem1p domain-containing proteins

21 January 2018

1 reference

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Keap1/Cullin3 Modulates p62/SQSTM1 Activity via UBA Domain Ubiquitination

21 January 2018

1 reference

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HECT E3 ubiquitin ligase Nedd4-1 ubiquitinates ACK and regulates epidermal growth factor (EGF)-induced degradation of EGF receptor and ACK

21 January 2018

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Serine 403 phosphorylation of p62/SQSTM1 regulates selective autophagic clearance of ubiquitinated proteins.

21 January 2018

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Geranylgeranylation signals to the Hippo pathway for breast cancer cell proliferation and migration.

21 January 2018

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Cell signaling and function organized by PB1 domain interactions.

21 January 2018

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Of the atypical PKCs, Par-4 and p62: recent understandings of the biology and pathology of a PB1-dominated complex

21 January 2018

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Transcriptional activation of p62/A170/ZIP during the formation of the aggregates: possible mechanisms and the role in Lewy body formation in Parkinson's disease

21 January 2018

1 reference

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TRIM21 Ubiquitylates SQSTM1/p62 and Suppresses Protein Sequestration to Regulate Redox Homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.207068

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.207068

Ubiquitylation of p62/sequestosome1 activates its autophagy receptor function and controls selective autophagy upon ubiquitin stress.

21 January 2018

1 reference

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Interaction of protein kinase C zeta with ZIP, a novel protein kinase C-binding protein

21 January 2018

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Interactions between autophagy receptors and ubiquitin-like proteins form the molecular basis for selective autophagy.

21 January 2018

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Localization of atypical protein kinase C isoforms into lysosome-targeted endosomes through interaction with p62.

21 January 2018

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The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation

21 January 2018

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Sequestosome 1/p62 is a polyubiquitin chain binding protein involved in ubiquitin proteasome degradation

21 January 2018

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Parkin promotes proteasomal degradation of p62: implication of selective vulnerability of neuronal cells in the pathogenesis of Parkinson's disease

21 January 2018

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Cargo recognition and trafficking in selective autophagy

21 January 2018

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Analysis of intracytoplasmic hyaline bodies in a hepatocellular carcinoma. Demonstration of p62 as major constituent

21 January 2018

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Mallory body--a disease-associated type of sequestosome

21 January 2018

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In vitro production of Mallory bodies and intracellular hyaline bodies: the central role of sequestosome 1/p62.

21 January 2018

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Lys-63-linked ubiquitination by E3 ubiquitin ligase Nedd4-1 facilitates endosomal sequestration of internalized α-synuclein

21 January 2018

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The E3 ubiquitin ligase NEDD4 is an LC3-interactive protein and regulates autophagy.

21 January 2018

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p62 Deficiency Enhances α-Synuclein Pathology in Mice.

21 January 2018

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Ubiquitin ligase Nedd4 promotes alpha-synuclein degradation by the endosomal-lysosomal pathway

21 January 2018

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Calcium activates Nedd4 E3 ubiquitin ligases by releasing the C2 domain-mediated auto-inhibition

21 January 2018

1 reference

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p62 Is a common component of cytoplasmic inclusions in protein aggregation diseases

21 January 2018

1 reference

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ATM functions at the peroxisome to induce pexophagy in response to ROS.

21 January 2018

1 reference

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The adaptor protein p62/SQSTM1 targets invading bacteria to the autophagy pathway.

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1242/JCS.207068

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29021346%20AND%20SRC:MED&resulttype=core&format=json

6 April 2020

1 reference