(Q48218342)

http://europepmc.org/abstract/MED/25195859

9 February 2018

title

p57Kip2 is an unrecognized DNA damage response effector molecule that functions in tumor suppression and chemoresistance. (English)

1 reference

http://europepmc.org/abstract/MED/25195859

9 February 2018

author

Qiao Zuo

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25195859%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

author name string

H Jia

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25195859%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Q Cong

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25195859%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

J F L Chua

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25195859%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

H Liu

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25195859%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

X Xia

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25195859%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

X Zhang

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25195859%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

J Lin

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25195859%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

S L Habib

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25195859%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

J Ao

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25195859%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

C Fu

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25195859%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

B Li

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25195859%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

language of work or name

English

0 references

publication date

8 September 2014

1 reference

http://europepmc.org/abstract/MED/25195859

9 February 2018

published in

Oncogene

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25195859%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

volume

34

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25195859%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

issue

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25195859%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

page(s)

3568-3581

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25195859%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/onc.2014.287

1 June 2020

exact match

0 references

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Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

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p57(KIP2) regulates radial glia and intermediate precursor cell cycle dynamics and lower layer neurogenesis in developing cerebral cortex

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Differentiation of trophoblast stem cells into giant cells is triggered by p57/Kip2 inhibition of CDK1 activity

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p57 controls adult neural stem cell quiescence and modulates the pace of lifelong neurogenesis

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p57(Kip2) and cancer: time for a critical appraisal.

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CDK inhibitor p57 (Kip2) is downregulated by Akt during HER2-mediated tumorigenicity

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CDKN1C (p57) is a direct target of EZH2 and suppressed by multiple epigenetic mechanisms in breast cancer cells

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Oppositely imprinted genes p57(Kip2) and igf2 interact in a mouse model for Beckwith-Wiedemann syndrome

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p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene

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Identification of 5-Iodotubercidin as a genotoxic drug with anti-cancer potential

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New insights into TGF-beta-Smad signalling

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Induction of p57(KIP2) expression by p73beta.

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CDKN1C/P57 is regulated by the Notch target gene Hes1 and induces senescence in human hepatocellular carcinoma

21 January 2018

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p38 MAPK/MK2-mediated induction of miR-34c following DNA damage prevents Myc-dependent DNA replication

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DNA damage activates a spatially distinct late cytoplasmic cell-cycle checkpoint network controlled by MK2-mediated RNA stabilization

21 January 2018

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A cytosolic ATM/NEMO/RIP1 complex recruits TAK1 to mediate the NF-kappaB and p38 mitogen-activated protein kinase (MAPK)/MAPK-activated protein 2 responses to DNA damage

21 January 2018

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p38 MAPK- and Akt-mediated p300 phosphorylation regulates its degradation to facilitate nucleotide excision repair

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AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosis

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Oxidative stress induces an ATM-independent senescence pathway through p38 MAPK-mediated lamin B1 accumulation

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TAO kinases mediate activation of p38 in response to DNA damage

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ATM-dependent phosphorylation of ATF2 is required for the DNA damage response

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Regulation of TIP60 by ATF2 modulates ATM activation

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Suppression of centrosome amplification after DNA damage depends on p27 accumulation

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21 January 2018

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p57(KIP2) control of actin cytoskeleton dynamics is responsible for its mitochondrial pro-apoptotic effect.

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p53-deficient cells rely on ATM- and ATR-mediated checkpoint signaling through the p38MAPK/MK2 pathway for survival after DNA damage

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21 January 2018

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21 January 2018

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21 January 2018

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p57 Is Required for Quiescence and Maintenance of Adult Hematopoietic Stem Cells

21 January 2018

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Downregulation of the KIP family members p27KIP1and p57KIP2by SKP2 and the role of methylation in p57KIP2inactivation in nonsmall cell lung cancer

21 January 2018

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Altered cell differentiation and proliferation in mice lacking p57KIP2 indicates a role in Beckwith–Wiedemann syndrome

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.287

p21(CIP1) and p57(KIP2) control muscle differentiation at the myogenin step

21 January 2018

1 reference

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BMP2 and BMP6 control p57(Kip2) expression and cell growth arrest/terminal differentiation in normal primary human epidermal keratinocytes

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.287

p57(Kip2) is degraded through the proteasome in osteoblasts stimulated to proliferation by transforming growth factor beta1

31 March 2020

1 reference

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The hallmarks of CDKN1C (p57, KIP2) in cancer

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25195859

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mouse embryos lacking Smad1 signals display defects in extra-embryonic tissues and germ cell formation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25195859