(Q48236271)

9 February 2018

title

Loss of FFA2 and FFA3 increases insulin secretion and improves glucose tolerance in type 2 diabetes (English)

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9 February 2018

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9 February 2018

Stefan Offermanns

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9 February 2018

Sorin Tunaru

object named as

Sorin Tunaru

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author name string

Cong Tang

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9 February 2018

Kashan Ahmed

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9 February 2018

Shun Lu

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9 February 2018

Hermann-Josef Gröne

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9 February 2018

language of work or name

English

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publication date

12 January 2015

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9 February 2018

published in

Nature Medicine

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9 February 2018

volume

21

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9 February 2018

issue

2

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9 February 2018

page(s)

173-177

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9 February 2018

https://scigraph.springernature.com/pub.10.1038/nm.3779

exact match

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cites work

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Butyrate and propionate protect against diet-induced obesity and regulate gut hormones via free fatty acid receptor 3-independent mechanisms

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The measurement of plasma acetate by a manual or automated technique in diabetic and non-diabetic subjects

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12 December 2020

Short-chain free fatty acid receptors FFA2/GPR43 and FFA3/GPR41 as new potential therapeutic targets

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12 December 2020

A protocol for islet isolation from mouse pancreas

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12 December 2020

Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41

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12 December 2020

Negative association of acetate with visceral adipose tissue and insulin levels

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12 December 2020

Pharmacology, physiology, and mechanisms of incretin hormone action

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12 December 2020

Targeting the pancreatic β-cell to treat diabetes

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12 December 2020

The Gq/G11-mediated signaling pathway is critical for autocrine potentiation of insulin secretion in mice

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12 December 2020

The fatty acid receptor FFA1/GPR40 a decade later: how much do we know?

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12 December 2020

Regulation of insulin secretion in human pancreatic islets

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12 December 2020

Lipid receptors and islet function: therapeutic implications?

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12 December 2020

Roles of short-chain fatty acids receptors, GPR41 and GPR43 on colonic functions.

1 reference

12 December 2020

Probing cell type-specific functions of Gi in vivo identifies GPCR regulators of insulin secretion.

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12 December 2020

A genetically engineered human pancreatic β cell line exhibiting glucose-inducible insulin secretion

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12 December 2020

Improved glucose control and reduced body fat mass in free fatty acid receptor 2-deficient mice fed a high-fat diet

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12 December 2020

Type 2 diabetes across generations: from pathophysiology to prevention and management

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12 December 2020

Male mice that lack the G-protein-coupled receptor GPR41 have low energy expenditure and increased body fat content.

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12 December 2020

Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase

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12 December 2020

The worldwide epidemiology of type 2 diabetes mellitus--present and future perspectives

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12 December 2020

Short-chain fatty acids stimulate glucagon-like peptide-1 secretion via the G-protein-coupled receptor FFAR2

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12 December 2020

Islet G protein-coupled receptors as potential targets for treatment of type 2 diabetes

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Novel insights into the function of β-cell M3 muscarinic acetylcholine receptors: therapeutic implications

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12 December 2020

Management of type 2 diabetes: new and future developments in treatment

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12 December 2020

The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids

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12 December 2020

Effect of ethanol, acetaldehyde, and acetate on insulin and glucagon secretion in the perfused rat pancreas

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12 December 2020

Origins of blood acetate in the rat

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12 December 2020

Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation

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Cis elements of the villin gene control expression in restricted domains of the vertical (crypt) and horizontal (duodenum, cecum) axes of the intestine.

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Rapid modification of bacterial artificial chromosomes by ET-recombination.

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Time of day and glucose tolerance status affect serum short-chain fatty acid concentrations in humans.

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12 December 2020

GPR41/FFAR3 and GPR43/FFAR2 as cosensors for short-chain fatty acids in enteroendocrine cells vs FFAR3 in enteric neurons and FFAR2 in enteric leukocytes

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12 December 2020

Plasma acetate turnover and oxidation

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12 December 2020

Chronic PYY3–36 treatment promotes fat oxidation and ameliorates insulin resistance in C57BL6 mice

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12 December 2020

Production of acetate in the liver and its utilization in peripheral tissues

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12 December 2020

Roles of GPR41 and GPR43 in leptin secretory responses of murine adipocytes to short chain fatty acids

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12 December 2020

International Union of Pharmacology. LXXI. Free fatty acid receptors FFA1, -2, and -3: pharmacology and pathophysiological functions

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12 December 2020

The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43.

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12 December 2020

Production rates and metabolism of short-chain fatty acids in the colon and whole body using stable isotopes.

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12 December 2020

Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms

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Overexpression of alpha2A-adrenergic receptors contributes to type 2 diabetes

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12 December 2020

Plasma acetate levels in a group of obese diabetic, obese normoglycemic, and control subjects and their relationships with other blood parameters

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12 December 2020

An autocrine lactate loop mediates insulin-dependent inhibition of lipolysis through GPR81.

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Isolation and culture of mouse intestinal cells

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Crossref

https://api.crossref.org/works/10.1038%2FNM.3779

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NM.3779

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9 February 2018

release_wev2e6r6p5f4npv6ugsw3esude

Fatcat ID

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9 February 2018